(62 nodes) Regulation of neuron differentiation network (Ixodes scapularis)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	B7P0X0_IXOSC	Ets2, putative. (609 aa)
	B7P3E6_IXOSC	P21-activated kinase, Putative. (139 aa)
	B7P3J2_IXOSC	Leukocyte tyrosine kinase receptor, putative. (662 aa)
	B7P4G7_IXOSC	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (291 aa)
	B7P4H4_IXOSC	PID domain-containing protein. (445 aa)
	B7P4X9_IXOSC	Phosphoinositide phospholipase C. (1201 aa)
	B7P8L1_IXOSC	Transcriptional repressor Yan, putative (Fragment). (328 aa)
	B7P9R7_IXOSC	Venom nerve growth factor, putative (Fragment). (70 aa)
	B7PCK6_IXOSC	Gap1, putative (Fragment). (747 aa)
	B7PCL3_IXOSC	Protein MICAL-3, putative (Fragment). (610 aa)
	B7PEB1_IXOSC	Sdk-P1, putative. (1754 aa)
	B7PGD2_IXOSC	Tyrosine protein phosphatase non-receptor type, putative. (1400 aa)
	B7PHT5_IXOSC	Suppressor of cytokine signaling-5, putative. (229 aa)
	B7PJ84_IXOSC	Headcase protein, putative. (427 aa)
	B7PKN3_IXOSC	Ubiquitin protein ligase; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	B7PL19_IXOSC	Tyrosine-protein kinase. (447 aa)
	B7PLG7_IXOSC	Integrator complex subunit, putative (Fragment). (1123 aa)
	B7PM20_IXOSC	Uncharacterized protein. (110 aa)
	B7PNY5_IXOSC	Integrator complex subunit, putative. (2125 aa)
	B7PRV7_IXOSC	Aryl hydrocarbon receptor, putative. (674 aa)
	B7PT49_IXOSC	Neural cell adhesion molecule, putative. (333 aa)
	B7PTX5_IXOSC	Diz domain-containing protein ccd, putative. (134 aa)
	B7PU01_IXOSC	Neuralized, putative. (457 aa)
	B7PUA8_IXOSC	Synaptic vesicle amine transporter, putative (Fragment). (485 aa)
	B7PUN0_IXOSC	Uncharacterized protein. (271 aa)
	B7PVH4_IXOSC	Tyrosine-protein kinase. (467 aa)
	B7PVH5_IXOSC	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (484 aa)
	B7PVS0_IXOSC	Brefeldin A-inhibited guanine nucleotide-exchange protein, putative. (1645 aa)
	B7PX45_IXOSC	Uncharacterized protein. (272 aa)
	B7PXX0_IXOSC	Integrator complex subunit 8 family protein. (190 aa)
	B7PXX5_IXOSC	Homeobox protein otx, putative. (203 aa)
	B7PYR0_IXOSC	C2H2-type domain-containing protein. (194 aa)
	B7PYR5_IXOSC	Hepatocellular carcinoma-associated antigen, putative. (226 aa)
	B7PYR7_IXOSC	Ccaat-binding transcription factor subunit A, putative (Fragment). (117 aa)
	B7Q0Y2_IXOSC	Ubiquitin protein ligase, putative; Belongs to the ubiquitin-conjugating enzyme family. (185 aa)
	B7Q122_IXOSC	Mitogen-activated protein kinase. (411 aa)
	B7Q199_IXOSC	RAS protein, putative (Fragment). (192 aa)
	B7Q1X0_IXOSC	Prospero protein, putative. (646 aa)
	B7Q2J4_IXOSC	Uncharacterized protein. (195 aa)
	B7Q5D7_IXOSC	Impact, putative. (293 aa)
	B7Q609_IXOSC	Cytoplasmic dynein heavy chain, putative (Fragment). (2827 aa)
	B7Q6K8_IXOSC	Phosphatidylinositol 3-kinase catalytic subunit, putative; Belongs to the PI3/PI4-kinase family. (491 aa)
	B7Q718_IXOSC	Homeobox domain-containing protein. (186 aa)
	B7Q8Z4_IXOSC	WD-repeat protein, putative (Fragment). (1581 aa)
	B7Q903_IXOSC	Pole hole family protein. (667 aa)
	B7Q973_IXOSC	Nk-2 homeobox protein, putative. (51 aa)
	B7Q9A2_IXOSC	Dedicator of cytokinesis protein, putative (Fragment); Belongs to the DOCK family. (1551 aa)
	B7QDG7_IXOSC	Cyclin T-dependent kinase CDK9, putative (Fragment); Belongs to the protein kinase superfamily. (461 aa)
	B7QE34_IXOSC	Serine/threonine protein kinase, putative. (284 aa)
	B7QEU8_IXOSC	Ubiquitin protein ligase, putative (Fragment); Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
	B7QF55_IXOSC	Protein tyrosine phosphatase, putative (Fragment). (556 aa)
	B7QFJ3_IXOSC	Ankyrin repeats containing protein, putative (Fragment). (309 aa)
	B7QFM0_IXOSC	Tyrosine kinase, putative. (442 aa)
	B7QHG3_IXOSC	Pdz domain-containing guanine nucleotide exchange factor, pdz-gef, putative. (1244 aa)
	B7QI53_IXOSC	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (686 aa)
	B7QIB0_IXOSC	DNA-binding protein inhibitor, putative. (197 aa)
	B7QJ44_IXOSC	Uncharacterized protein. (131 aa)
	B7QJF5_IXOSC	Phosphatidylinositol 3-kinase catalytic subunit, putative (Fragment); Belongs to the PI3/PI4-kinase family. (617 aa)
	B7QMT7_IXOSC	Uncharacterized protein. (549 aa)
	B7QNE2_IXOSC	HMG-box transcription factor, putative. (393 aa)
	B7QNG7_IXOSC	Ig-like domain-containing protein. (85 aa)
	B7QNX4_IXOSC	Aryl hydrocarbon receptor nuclear translocator, putative (Fragment). (382 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P0X0_IXOSC	B7QIB0_IXOSC	B7P0X0	B7QIB0	Ets2, putative.	DNA-binding protein inhibitor, putative.	0.401
B7P3E6_IXOSC	B7PL19_IXOSC	B7P3E6	B7PL19	P21-activated kinase, Putative.	Tyrosine-protein kinase.	0.403
B7P3E6_IXOSC	B7PVH4_IXOSC	B7P3E6	B7PVH4	P21-activated kinase, Putative.	Tyrosine-protein kinase.	0.403
B7P3E6_IXOSC	B7QFJ3_IXOSC	B7P3E6	B7QFJ3	P21-activated kinase, Putative.	Ankyrin repeats containing protein, putative (Fragment).	0.436
B7P3J2_IXOSC	B7P4X9_IXOSC	B7P3J2	B7P4X9	Leukocyte tyrosine kinase receptor, putative.	Phosphoinositide phospholipase C.	0.733
B7P3J2_IXOSC	B7PL19_IXOSC	B7P3J2	B7PL19	Leukocyte tyrosine kinase receptor, putative.	Tyrosine-protein kinase.	0.585
B7P3J2_IXOSC	B7PVH4_IXOSC	B7P3J2	B7PVH4	Leukocyte tyrosine kinase receptor, putative.	Tyrosine-protein kinase.	0.585
B7P3J2_IXOSC	B7Q122_IXOSC	B7P3J2	B7Q122	Leukocyte tyrosine kinase receptor, putative.	Mitogen-activated protein kinase.	0.429
B7P3J2_IXOSC	B7Q6K8_IXOSC	B7P3J2	B7Q6K8	Leukocyte tyrosine kinase receptor, putative.	Phosphatidylinositol 3-kinase catalytic subunit, putative; Belongs to the PI3/PI4-kinase family.	0.586
B7P3J2_IXOSC	B7QF55_IXOSC	B7P3J2	B7QF55	Leukocyte tyrosine kinase receptor, putative.	Protein tyrosine phosphatase, putative (Fragment).	0.623
B7P3J2_IXOSC	B7QJF5_IXOSC	B7P3J2	B7QJF5	Leukocyte tyrosine kinase receptor, putative.	Phosphatidylinositol 3-kinase catalytic subunit, putative (Fragment); Belongs to the PI3/PI4-kinase family.	0.586
B7P4G7_IXOSC	B7PKN3_IXOSC	B7P4G7	B7PKN3	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Ubiquitin protein ligase; Belongs to the ubiquitin-conjugating enzyme family.	0.445
B7P4G7_IXOSC	B7Q0Y2_IXOSC	B7P4G7	B7Q0Y2	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Ubiquitin protein ligase, putative; Belongs to the ubiquitin-conjugating enzyme family.	0.445
B7P4G7_IXOSC	B7QEU8_IXOSC	B7P4G7	B7QEU8	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Ubiquitin protein ligase, putative (Fragment); Belongs to the ubiquitin-conjugating enzyme family.	0.445
B7P4X9_IXOSC	B7P3J2_IXOSC	B7P4X9	B7P3J2	Phosphoinositide phospholipase C.	Leukocyte tyrosine kinase receptor, putative.	0.733
B7P4X9_IXOSC	B7P9R7_IXOSC	B7P4X9	B7P9R7	Phosphoinositide phospholipase C.	Venom nerve growth factor, putative (Fragment).	0.483
B7P4X9_IXOSC	B7PL19_IXOSC	B7P4X9	B7PL19	Phosphoinositide phospholipase C.	Tyrosine-protein kinase.	0.516
B7P4X9_IXOSC	B7PVH4_IXOSC	B7P4X9	B7PVH4	Phosphoinositide phospholipase C.	Tyrosine-protein kinase.	0.516
B7P4X9_IXOSC	B7Q6K8_IXOSC	B7P4X9	B7Q6K8	Phosphoinositide phospholipase C.	Phosphatidylinositol 3-kinase catalytic subunit, putative; Belongs to the PI3/PI4-kinase family.	0.943
B7P4X9_IXOSC	B7QF55_IXOSC	B7P4X9	B7QF55	Phosphoinositide phospholipase C.	Protein tyrosine phosphatase, putative (Fragment).	0.516