STRINGSTRING
B7PYP0_IXOSC B7PYP0_IXOSC B7PYC7_IXOSC B7PYC7_IXOSC B7PXK9_IXOSC B7PXK9_IXOSC B7PXK8_IXOSC B7PXK8_IXOSC B7PXK7_IXOSC B7PXK7_IXOSC B7PX81_IXOSC B7PX81_IXOSC B7PWG9_IXOSC B7PWG9_IXOSC B7PVS2_IXOSC B7PVS2_IXOSC B7PVJ0_IXOSC B7PVJ0_IXOSC B7PVH2_IXOSC B7PVH2_IXOSC B7PU24_IXOSC B7PU24_IXOSC B7PU22_IXOSC B7PU22_IXOSC B7PU21_IXOSC B7PU21_IXOSC B7PU17_IXOSC B7PU17_IXOSC B7PST4_IXOSC B7PST4_IXOSC B7PSJ4_IXOSC B7PSJ4_IXOSC B7PRI2_IXOSC B7PRI2_IXOSC B7PQZ2_IXOSC B7PQZ2_IXOSC B7PQS5_IXOSC B7PQS5_IXOSC B7PQ80_IXOSC B7PQ80_IXOSC B7PP79_IXOSC B7PP79_IXOSC B7PNQ2_IXOSC B7PNQ2_IXOSC B7PNQ1_IXOSC B7PNQ1_IXOSC B7PNJ5_IXOSC B7PNJ5_IXOSC B7PN89_IXOSC B7PN89_IXOSC B7PN68_IXOSC B7PN68_IXOSC B7PN15_IXOSC B7PN15_IXOSC B7PLW5_IXOSC B7PLW5_IXOSC B7PLM1_IXOSC B7PLM1_IXOSC B7PLJ5_IXOSC B7PLJ5_IXOSC B7PKZ6_IXOSC B7PKZ6_IXOSC B7PKZ3_IXOSC B7PKZ3_IXOSC CYTLG_IXOSC CYTLG_IXOSC CYTL2_IXOSC CYTL2_IXOSC B7PKZ0_IXOSC B7PKZ0_IXOSC B7PKW4_IXOSC B7PKW4_IXOSC B7PK06_IXOSC B7PK06_IXOSC B7PJG0_IXOSC B7PJG0_IXOSC B7PI18_IXOSC B7PI18_IXOSC B7PH24_IXOSC B7PH24_IXOSC B7PGP4_IXOSC B7PGP4_IXOSC B7PGN7_IXOSC B7PGN7_IXOSC B7PF95_IXOSC B7PF95_IXOSC B7PF58_IXOSC B7PF58_IXOSC B7PEZ7_IXOSC B7PEZ7_IXOSC B7PEF3_IXOSC B7PEF3_IXOSC B7PE74_IXOSC B7PE74_IXOSC B7PDJ3_IXOSC B7PDJ3_IXOSC B7PBV5_IXOSC B7PBV5_IXOSC B7PCZ6_IXOSC B7PCZ6_IXOSC B7PAU7_IXOSC B7PAU7_IXOSC B7PAL7_IXOSC B7PAL7_IXOSC B7P761_IXOSC B7P761_IXOSC B7P760_IXOSC B7P760_IXOSC B7P627_IXOSC B7P627_IXOSC B7P626_IXOSC B7P626_IXOSC B7P4X2_IXOSC B7P4X2_IXOSC B7P4H2_IXOSC B7P4H2_IXOSC B7P4B2_IXOSC B7P4B2_IXOSC B7P3L9_IXOSC B7P3L9_IXOSC B7P2Z9_IXOSC B7P2Z9_IXOSC B7P2R8_IXOSC B7P2R8_IXOSC B7P1Y3_IXOSC B7P1Y3_IXOSC B7P1G8_IXOSC B7P1G8_IXOSC B7P0Y0_IXOSC B7P0Y0_IXOSC B7QP26_IXOSC B7QP26_IXOSC B7QP11_IXOSC B7QP11_IXOSC B7QNY6_IXOSC B7QNY6_IXOSC B7QNY0_IXOSC B7QNY0_IXOSC B7QMX5_IXOSC B7QMX5_IXOSC B7QMC8_IXOSC B7QMC8_IXOSC B7QM31_IXOSC B7QM31_IXOSC B7QLU5_IXOSC B7QLU5_IXOSC B7QL37_IXOSC B7QL37_IXOSC B7QL36_IXOSC B7QL36_IXOSC B7QL35_IXOSC B7QL35_IXOSC B7QL34_IXOSC B7QL34_IXOSC B7QL33_IXOSC B7QL33_IXOSC B7QL32_IXOSC B7QL32_IXOSC B7QL31_IXOSC B7QL31_IXOSC B7QL30_IXOSC B7QL30_IXOSC B7QKZ7_IXOSC B7QKZ7_IXOSC B7QKH4_IXOSC B7QKH4_IXOSC B7QK85_IXOSC B7QK85_IXOSC B7QJS7_IXOSC B7QJS7_IXOSC B7QJF1_IXOSC B7QJF1_IXOSC B7QJF0_IXOSC B7QJF0_IXOSC B7QJ51_IXOSC B7QJ51_IXOSC B7QH66_IXOSC B7QH66_IXOSC B7QEK6_IXOSC B7QEK6_IXOSC B7QDW7_IXOSC B7QDW7_IXOSC B7QD24_IXOSC B7QD24_IXOSC B7QCX0_IXOSC B7QCX0_IXOSC B7QCI6_IXOSC B7QCI6_IXOSC B7QAK0_IXOSC B7QAK0_IXOSC B7Q8M7_IXOSC B7Q8M7_IXOSC B7Q8G3_IXOSC B7Q8G3_IXOSC B7Q806_IXOSC B7Q806_IXOSC B7Q7W3_IXOSC B7Q7W3_IXOSC B7Q7F6_IXOSC B7Q7F6_IXOSC B7Q773_IXOSC B7Q773_IXOSC B7Q728_IXOSC B7Q728_IXOSC B7Q690_IXOSC B7Q690_IXOSC B7Q685_IXOSC B7Q685_IXOSC B7Q683_IXOSC B7Q683_IXOSC B7Q629_IXOSC B7Q629_IXOSC B7Q5W6_IXOSC B7Q5W6_IXOSC B7Q5W5_IXOSC B7Q5W5_IXOSC B7Q5W3_IXOSC B7Q5W3_IXOSC B7Q5R4_IXOSC B7Q5R4_IXOSC B7Q4Y7_IXOSC B7Q4Y7_IXOSC B7Q3H4_IXOSC B7Q3H4_IXOSC B7Q3H2_IXOSC B7Q3H2_IXOSC B7Q3H1_IXOSC B7Q3H1_IXOSC B7Q344_IXOSC B7Q344_IXOSC B7Q2U8_IXOSC B7Q2U8_IXOSC B7Q1E2_IXOSC B7Q1E2_IXOSC B7Q0E8_IXOSC B7Q0E8_IXOSC B7PZL4_IXOSC B7PZL4_IXOSC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
B7PYP0_IXOSCPolyhomeotic, putative. (322 aa)
B7PYC7_IXOSCFibropellin-1, putative (Fragment). (665 aa)
B7PXK9_IXOSCUncharacterized protein. (215 aa)
B7PXK8_IXOSCAlpha-macroglobulin, putative (Fragment). (231 aa)
B7PXK7_IXOSCAlpha-macroglobulin, putative. (287 aa)
B7PX81_IXOSCSerpin, putative; Belongs to the serpin family. (402 aa)
B7PWG9_IXOSCSerine protease inhibitor, putative (Fragment). (66 aa)
B7PVS2_IXOSCCOP9 signalosome, subunit CSN5, putative. (257 aa)
B7PVJ0_IXOSCThrombin inhibitor, putative; Belongs to the serpin family. (174 aa)
B7PVH2_IXOSCMitogen-activated protein kinase, putative; Belongs to the protein kinase superfamily. (436 aa)
B7PU24_IXOSCAlpha-2-macroglobulin, putative (Fragment). (413 aa)
B7PU22_IXOSCAlpha-macroglobulin, putative (Fragment). (181 aa)
B7PU21_IXOSCAlpha-macroglobulin, putative (Fragment). (146 aa)
B7PU17_IXOSCColostrum trypsin inhibitor, putative. (79 aa)
B7PST4_IXOSCSerpin-4 precursor, putative; Belongs to the serpin family. (213 aa)
B7PSJ4_IXOSCAlpha2-macroglobulin family N-terminal region domain-containing protein. (574 aa)
B7PRI2_IXOSCCystine-binding periplasmic protein, putative; Belongs to the serpin family. (178 aa)
B7PQZ2_IXOSCLAM_G_DOMAIN domain-containing protein. (191 aa)
B7PQS5_IXOSCKunitz-type proteinase inhibitor 5 II, putative (Fragment). (58 aa)
B7PQ80_IXOSCSecreted protein with Kunitz domain, putative (Fragment). (61 aa)
B7PP79_IXOSCSerine protease inhibitor, putative (Fragment). (69 aa)
B7PNQ2_IXOSCSerpin, putative (Fragment); Belongs to the serpin family. (602 aa)
B7PNQ1_IXOSCSerpin, putative; Belongs to the serpin family. (151 aa)
B7PNJ5_IXOSCSerine proteinase inhibitor, putative. (123 aa)
B7PN89_IXOSCSerpin-2 precursor, putative; Belongs to the serpin family. (276 aa)
B7PN68_IXOSCUncharacterized protein. (228 aa)
B7PN15_IXOSCUbiquitin carboxyl-terminal hydrolase. (844 aa)
B7PLW5_IXOSCSerpin, putative (Fragment); Belongs to the serpin family. (180 aa)
B7PLM1_IXOSCTissue inhibitor of metalloproteinase, putative. (161 aa)
B7PLJ5_IXOSCUbiquitin-conjugating enzyme, putative. (284 aa)
B7PKZ6_IXOSCSerpin 2 precursor, putative; Belongs to the serpin family. (375 aa)
B7PKZ3_IXOSCSecreted cystatin, putative; Belongs to the cystatin family. (134 aa)
CYTLG_IXOSCSalivary cystatin-L; Inhibitor of cysteine proteinases. Inhibits host immune responses via its inhibition of host cathepsins. Contributes to the suppression of the host's immune response to tick salivary proteins and is important for successful feeding on hosts. Inhibits differentiation of host dendritic cells. Inhibits proliferation of host T-cells in response to antigen stimulus. Down-regulates TLR2-mediated host responses to infection by B.burgdorferi and the production of the chemokine CCL3 by host dendritic cells. Down-regulates host responses to infection by B.burgdorferi and the [...] (133 aa)
CYTL2_IXOSCSalivary cystatin-L2; Inhibitor of cysteine proteinases. Inhibits host immune responses, probably via its inhibition of host cathepsins. Contributes to the suppression of the host's immune response to tick salivary proteins and is important for successful feeding on hosts. Down-regulates TLR2-mediated host responses to infection by B.burgdorferi and the production of chemokines CCL3 and CXCL10 by host dendritic cells. Enhances infection by the tick-transmitted pathogen B.burgdorferi (in vitro). Inhibits host inflammatory responses to A.phagocytophilum infection. Inhibits papain (in vit [...] (132 aa)
B7PKZ0_IXOSCSecreted cystatin, putative; Belongs to the cystatin family. (133 aa)
B7PKW4_IXOSCZinc finger protein, putative. (344 aa)
B7PK06_IXOSCSAPK substrate protein 1-A, putative. (164 aa)
B7PJG0_IXOSCUncharacterized protein. (83 aa)
B7PI18_IXOSCAlpha-macroglobulin, putative. (1040 aa)
B7PH24_IXOSCSerine protease inhibitor, putative; Belongs to the serpin family. (703 aa)
B7PGP4_IXOSCSerpin 2 precursor, putative; Belongs to the serpin family. (394 aa)
B7PGN7_IXOSCSerpin, putative; Belongs to the serpin family. (127 aa)
B7PF95_IXOSCX-linked inhibitor of apotosis protein, putative. (302 aa)
B7PF58_IXOSCGas1 protein, putative. (223 aa)
B7PEZ7_IXOSCSerine protease inhibitor, putative (Fragment). (870 aa)
B7PEF3_IXOSCSuperoxide dismutase, putative. (200 aa)
B7PE74_IXOSCSerine proteinase inhibitor, putative. (193 aa)
B7PDJ3_IXOSCApoptosis inhibitor IAP, putative (Fragment). (198 aa)
B7PBV5_IXOSCSecreted salivary gland peptide, putative (Fragment). (267 aa)
B7PCZ6_IXOSCUncharacterized protein. (1472 aa)
B7PAU7_IXOSCSerpin 7 precursor, putative; Belongs to the serpin family. (354 aa)
B7PAL7_IXOSCNEFA-interacting nuclear protein NIP30, putative. (158 aa)
B7P761_IXOSCLow-density lipoprotein receptor, putative (Fragment). (1500 aa)
B7P760_IXOSCVPS10 domain-containing receptor SorCS2, putative (Fragment). (575 aa)
B7P627_IXOSCKunitz domain-containing protein, putative (Fragment). (62 aa)
B7P626_IXOSCColostrum trypsin inhibitor, putative (Fragment). (62 aa)
B7P4X2_IXOSCPIH1_CS domain-containing protein. (104 aa)
B7P4H2_IXOSCRegulator of the ubiquitin pathway, putative (Fragment). (586 aa)
B7P4B2_IXOSCThrombin inhibitor, putative; Belongs to the serpin family. (374 aa)
B7P3L9_IXOSCSerine protease inhibitor, putative. (179 aa)
B7P2Z9_IXOSCSerpin, putative (Fragment); Belongs to the serpin family. (158 aa)
B7P2R8_IXOSCSerpin-2, putative; Belongs to the serpin family. (183 aa)
B7P1Y3_IXOSCNefa_Nip30_N domain-containing protein. (85 aa)
B7P1G8_IXOSCSerpin, putative; Belongs to the serpin family. (391 aa)
B7P0Y0_IXOSCMyeloid differentiation antigen family protein. (370 aa)
B7QP26_IXOSCSerpin-8 precursor, putative; Belongs to the serpin family. (177 aa)
B7QP11_IXOSCApoptosis inhibitor IAP, putative. (282 aa)
B7QNY6_IXOSCSerine proteinase inhibitor serpin-3, putative; Belongs to the serpin family. (396 aa)
B7QNY0_IXOSCSerpin-2, putative; Belongs to the serpin family. (396 aa)
B7QMX5_IXOSCSalivary protein KUN-5, putative. (148 aa)
B7QMC8_IXOSCAlpha-macroglobulin, putative (Fragment). (1092 aa)
B7QM31_IXOSCSerpin, putative; Belongs to the serpin family. (469 aa)
B7QLU5_IXOSCSerpin-2 precursor, putative; Belongs to the serpin family. (365 aa)
B7QL37_IXOSCSerpin-1 precursor, putative; Belongs to the serpin family. (176 aa)
B7QL36_IXOSCSerpin-4 precursor, putative; Belongs to the serpin family. (393 aa)
B7QL35_IXOSCSecreted salivary gland peptide, putative; Belongs to the serpin family. (289 aa)
B7QL34_IXOSCSecreted salivary gland peptide, putative; Belongs to the serpin family. (393 aa)
B7QL33_IXOSCSerpin-4 precursor, putative; Belongs to the serpin family. (392 aa)
B7QL32_IXOSCSecreted salivary gland peptide, putative; Belongs to the serpin family. (463 aa)
B7QL31_IXOSCSerpin-1 precursor, putative; Belongs to the serpin family. (390 aa)
B7QL30_IXOSCSerpin-2, putative; Belongs to the serpin family. (234 aa)
B7QKZ7_IXOSCIxolaris 2A, putative (Fragment). (86 aa)
B7QKH4_IXOSCAlpha-macroglobulin, putative (Fragment). (308 aa)
B7QK85_IXOSCSerine protease inhibitor, putative (Fragment). (89 aa)
B7QJS7_IXOSCSalivary protein KUN-5, putative. (165 aa)
B7QJF1_IXOSCSerpin-8 precursor, putative; Belongs to the serpin family. (455 aa)
B7QJF0_IXOSCSerpin, putative (Fragment); Belongs to the serpin family. (128 aa)
B7QJ51_IXOSCSerpin, putative; Belongs to the serpin family. (105 aa)
B7QH66_IXOSCCrystallin, alpha B, putative (Fragment); Belongs to the small heat shock protein (HSP20) family. (182 aa)
B7QEK6_IXOSCTransmembrane protein, putative. (240 aa)
B7QDW7_IXOSCSecreted salivary gland peptide, putative. (287 aa)
B7QD24_IXOSCSecreted salivary gland peptide, putative. (87 aa)
B7QCX0_IXOSCAlpha2-macroglobulin family N-terminal region domain-containing protein. (338 aa)
B7QCI6_IXOSCF-spondin, putative. (664 aa)
B7QAK0_IXOSCTrypsin inhibitor, putative. (55 aa)
B7Q8M7_IXOSCSerpin-2 precursor, putative; Belongs to the serpin family. (350 aa)
B7Q8G3_IXOSCSecreted salivary gland peptide, putative. (87 aa)
B7Q806_IXOSCCystatin-2 precursor, putative; Belongs to the cystatin family. (167 aa)
B7Q7W3_IXOSCSecreted salivary gland peptide, putative. (326 aa)
B7Q7F6_IXOSCInhibitor of apoptosis protein 1 and 2, iap1, iap2, putative. (501 aa)
B7Q773_IXOSCKunitz domain protein, putative (Fragment). (88 aa)
B7Q728_IXOSCTrypsin inhibitor, putative. (87 aa)
B7Q690_IXOSCSerine/threonine protein kinase, putative (Fragment). (473 aa)
B7Q685_IXOSCSerpin 2 precursor, putative; Belongs to the serpin family. (385 aa)
B7Q683_IXOSCSerpin 2 precursor, putative; Belongs to the serpin family. (394 aa)
B7Q629_IXOSCTumor necrosis factor induced protein, putative. (200 aa)
B7Q5W6_IXOSCSerpin-2 precursor, putative; Belongs to the serpin family. (249 aa)
B7Q5W5_IXOSCSerpin, putative; Belongs to the serpin family. (121 aa)
B7Q5W3_IXOSCSerpin-2 precursor, putative; Belongs to the serpin family. (374 aa)
B7Q5R4_IXOSCSecreted protein, putative. (118 aa)
B7Q4Y7_IXOSCPIH1 domain-containing protein, putative. (189 aa)
B7Q3H4_IXOSCAutoantigen, putative (Fragment). (128 aa)
B7Q3H2_IXOSCSerine proteinase inhibitor, putative (Fragment). (336 aa)
B7Q3H1_IXOSCSerine protease inhibitor, putative (Fragment). (79 aa)
B7Q344_IXOSCProteasome inhibitor, putative. (177 aa)
B7Q2U8_IXOSCSerpin, putative; Belongs to the serpin family. (129 aa)
B7Q1E2_IXOSCThioester-containing protein, putative. (1475 aa)
B7Q0E8_IXOSCSerpin 7 precursor, putative; Belongs to the serpin family. (374 aa)
B7PZL4_IXOSCSerine protease inhibitor, putative. (70 aa)
Your Current Organism:
Ixodes scapularis
NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick
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