(43 nodes) Regulation of embryonic development network (Ixodes scapularis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7QM84_IXOSC	Uncharacterized protein. (325 aa)
	B7QJN9_IXOSC	Uncharacterized protein. (1377 aa)
	B7QI72_IXOSC	Collybistin II, putative (Fragment). (348 aa)
	B7QI70_IXOSC	Regulator of g protein signalling family domaincontaining protein. (973 aa)
	B7QHU0_IXOSC	Traf2 and nck interacting kinase, tnik, putative. (1290 aa)
	B7QHG3_IXOSC	Pdz domain-containing guanine nucleotide exchange factor, pdz-gef, putative. (1244 aa)
	B7QG93_IXOSC	Uncharacterized protein. (573 aa)
	B7Q9Y0_IXOSC	DNA topoisomerase I, putative. (499 aa)
	B7Q7X6_IXOSC	LAM_G_DOMAIN domain-containing protein. (372 aa)
	B7Q7X5_IXOSC	Laminin alpha-4 chain, putative. (807 aa)
	B7Q6Z2_IXOSC	Transmembrane protein, putative. (645 aa)
	B7Q6A0_IXOSC	RNA binding motif-containing protein, putative (Fragment). (81 aa)
	B7Q5M2_IXOSC	Protein held out wings, putative. (329 aa)
	B7Q5I7_IXOSC	Class d atypical gprotein coupled receptor gprgbb4, putative. (210 aa)
	B7Q3T6_IXOSC	THO complex subunit, putative. (340 aa)
	B7Q2Y0_IXOSC	Tyrosine-protein kinase. (457 aa)
	B7Q2J4_IXOSC	Uncharacterized protein. (195 aa)
	B7Q199_IXOSC	RAS protein, putative (Fragment). (192 aa)
	B7Q0X8_IXOSC	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	B7PZ77_IXOSC	NFRKB_winged domain-containing protein. (401 aa)
	B7PYM7_IXOSC	Mbip protein, putative. (268 aa)
	B7PXP6_IXOSC	GlycyltRNA synthetase subunit beta, putative. (113 aa)
	B7PWJ1_IXOSC	Grb2 associated binder (Gab), putative. (212 aa)
	B7PTH6_IXOSC	Tight junction protein tama, putative; Belongs to the MAGUK family. (1421 aa)
	B7PT90_IXOSC	Wiskott-aldrich syndrome protein, putative (Fragment). (476 aa)
	B7PSP3_IXOSC	Non-specific protein-tyrosine kinase. (674 aa)
	B7PQ23_IXOSC	Cuticulin, putative (Fragment). (268 aa)
	B7PP03_IXOSC	Laminin subunit beta-1, putative (Fragment). (188 aa)
	B7PN76_IXOSC	Tyrosine kinase, putative (Fragment). (455 aa)
	B7PN45_IXOSC	Laminin alpha-1, 2 chain, putative. (615 aa)
	B7PN44_IXOSC	Netrin-4, putative. (370 aa)
	B7PM04_IXOSC	Uncharacterized protein. (587 aa)
	B7PKK5_IXOSC	GTPase Rho, putative. (82 aa)
	B7PH66_IXOSC	GTPase Rho, putative. (192 aa)
	B7PH65_IXOSC	GTPase Rho, putative (Fragment). (205 aa)
	B7PH64_IXOSC	Cdc42 protein, putative. (201 aa)
	B7PFE4_IXOSC	FHA domaincontaining protein. (774 aa)
	B7P8X6_IXOSC	Cdc42 protein, putative (Fragment). (238 aa)
	B7P604_IXOSC	Guanine nucleotide-binding protein G, putative. (209 aa)
	B7P4T8_IXOSC	Tyrosine protein kinase, putative. (1097 aa)
	B7P283_IXOSC	Zinc finger protein, putative. (199 aa)
	B7P1S6_IXOSC	Uncharacterized protein. (646 aa)
	B7P1J6_IXOSC	GTPase Rho, putative. (228 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P1J6_IXOSC	B7P604_IXOSC	B7P1J6	B7P604	GTPase Rho, putative.	Guanine nucleotide-binding protein G, putative.	0.478
B7P1J6_IXOSC	B7PSP3_IXOSC	B7P1J6	B7PSP3	GTPase Rho, putative.	Non-specific protein-tyrosine kinase.	0.407
B7P1J6_IXOSC	B7PT90_IXOSC	B7P1J6	B7PT90	GTPase Rho, putative.	Wiskott-aldrich syndrome protein, putative (Fragment).	0.539
B7P1J6_IXOSC	B7PTH6_IXOSC	B7P1J6	B7PTH6	GTPase Rho, putative.	Tight junction protein tama, putative; Belongs to the MAGUK family.	0.425
B7P1J6_IXOSC	B7Q3T6_IXOSC	B7P1J6	B7Q3T6	GTPase Rho, putative.	THO complex subunit, putative.	0.422
B7P1J6_IXOSC	B7QI70_IXOSC	B7P1J6	B7QI70	GTPase Rho, putative.	Regulator of g protein signalling family domaincontaining protein.	0.648
B7P1J6_IXOSC	B7QI72_IXOSC	B7P1J6	B7QI72	GTPase Rho, putative.	Collybistin II, putative (Fragment).	0.648
B7P4T8_IXOSC	B7PN76_IXOSC	B7P4T8	B7PN76	Tyrosine protein kinase, putative.	Tyrosine kinase, putative (Fragment).	0.448
B7P4T8_IXOSC	B7PSP3_IXOSC	B7P4T8	B7PSP3	Tyrosine protein kinase, putative.	Non-specific protein-tyrosine kinase.	0.433
B7P4T8_IXOSC	B7Q5M2_IXOSC	B7P4T8	B7Q5M2	Tyrosine protein kinase, putative.	Protein held out wings, putative.	0.405
B7P4T8_IXOSC	B7QI70_IXOSC	B7P4T8	B7QI70	Tyrosine protein kinase, putative.	Regulator of g protein signalling family domaincontaining protein.	0.571
B7P4T8_IXOSC	B7QI72_IXOSC	B7P4T8	B7QI72	Tyrosine protein kinase, putative.	Collybistin II, putative (Fragment).	0.571
B7P604_IXOSC	B7P1J6_IXOSC	B7P604	B7P1J6	Guanine nucleotide-binding protein G, putative.	GTPase Rho, putative.	0.478
B7P604_IXOSC	B7P8X6_IXOSC	B7P604	B7P8X6	Guanine nucleotide-binding protein G, putative.	Cdc42 protein, putative (Fragment).	0.478
B7P604_IXOSC	B7PH64_IXOSC	B7P604	B7PH64	Guanine nucleotide-binding protein G, putative.	Cdc42 protein, putative.	0.478
B7P604_IXOSC	B7PH65_IXOSC	B7P604	B7PH65	Guanine nucleotide-binding protein G, putative.	GTPase Rho, putative (Fragment).	0.478
B7P604_IXOSC	B7PH66_IXOSC	B7P604	B7PH66	Guanine nucleotide-binding protein G, putative.	GTPase Rho, putative.	0.478
B7P604_IXOSC	B7PKK5_IXOSC	B7P604	B7PKK5	Guanine nucleotide-binding protein G, putative.	GTPase Rho, putative.	0.478
B7P604_IXOSC	B7Q0X8_IXOSC	B7P604	B7Q0X8	Guanine nucleotide-binding protein G, putative.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.603
B7P604_IXOSC	B7Q3T6_IXOSC	B7P604	B7Q3T6	Guanine nucleotide-binding protein G, putative.	THO complex subunit, putative.	0.911