(28 nodes) Vascular endothelial growth factor receptor signaling pathway network (Ixodes scapularis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	B7P0R2_IXOSC	C. elegans sem-5, putative. (211 aa)
	B7P5V5_IXOSC	RAC serine/threonine kinase, putative; Belongs to the protein kinase superfamily. (345 aa)
	B7P8L1_IXOSC	Transcriptional repressor Yan, putative (Fragment). (328 aa)
	B7P9M2_IXOSC	Kinase suppressor of Ras (KSR), putative (Fragment). (916 aa)
	B7P9N2_IXOSC	Dock-1, putative (Fragment); Belongs to the DOCK family. (1613 aa)
	B7P9S6_IXOSC	Non-specific serine/threonine protein kinase. (344 aa)
	B7PDA6_IXOSC	PDGF_2 domain-containing protein. (77 aa)
	B7PDA7_IXOSC	Placenta growth factor, putative; Belongs to the PDGF/VEGF growth factor family. (149 aa)
	B7PEL7_IXOSC	Signal transduction protein lnk-realted, putative. (553 aa)
	B7PHG1_IXOSC	cAMP-dependent protein kinase catalytic subunit, putative; Belongs to the protein kinase superfamily. (371 aa)
	B7PKS1_IXOSC	Receptor protein-tyrosine kinase. (1083 aa)
	B7PN76_IXOSC	Tyrosine kinase, putative (Fragment). (455 aa)
	B7PP73_IXOSC	Mitogen-activated protein kinase kinase MKK4, putative (Fragment); Belongs to the protein kinase superfamily. (385 aa)
	B7PQ59_IXOSC	Ras GTP exchange factor, son of sevenless, putative (Fragment). (1034 aa)
	B7PSQ2_IXOSC	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (176 aa)
	B7PTK2_IXOSC	Eukaryotic translation initiation factor 4E binding protein, putative. (125 aa)
	B7PVJ6_IXOSC	Mitogen-activated protein kinase kinase MKK4, putative. (364 aa)
	B7Q0D1_IXOSC	Engulfment and cell motility protein, putative. (711 aa)
	B7Q122_IXOSC	Mitogen-activated protein kinase. (411 aa)
	B7Q1P4_IXOSC	Shc transforming protein, putative (Fragment). (461 aa)
	B7Q2R0_IXOSC	Adaptor protein Crk, putative (Fragment). (310 aa)
	B7Q6K8_IXOSC	Phosphatidylinositol 3-kinase catalytic subunit, putative; Belongs to the PI3/PI4-kinase family. (491 aa)
	B7Q6M8_IXOSC	VEGF183 protein, putative; Belongs to the PDGF/VEGF growth factor family. (308 aa)
	B7Q7M8_IXOSC	Engulfment and cell motility protein, putative. (730 aa)
	B7Q903_IXOSC	Pole hole family protein. (667 aa)
	B7QJF5_IXOSC	Phosphatidylinositol 3-kinase catalytic subunit, putative (Fragment); Belongs to the PI3/PI4-kinase family. (617 aa)
	B7QJT0_IXOSC	Rho guanine nucleotide exchange factor, putative (Fragment). (572 aa)
	B7QK86_IXOSC	Centromere protein b, putative. (883 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P0R2_IXOSC	B7P5V5_IXOSC	B7P0R2	B7P5V5	C. elegans sem-5, putative.	RAC serine/threonine kinase, putative; Belongs to the protein kinase superfamily.	0.465
B7P0R2_IXOSC	B7P9M2_IXOSC	B7P0R2	B7P9M2	C. elegans sem-5, putative.	Kinase suppressor of Ras (KSR), putative (Fragment).	0.585
B7P0R2_IXOSC	B7PEL7_IXOSC	B7P0R2	B7PEL7	C. elegans sem-5, putative.	Signal transduction protein lnk-realted, putative.	0.768
B7P0R2_IXOSC	B7PHG1_IXOSC	B7P0R2	B7PHG1	C. elegans sem-5, putative.	cAMP-dependent protein kinase catalytic subunit, putative; Belongs to the protein kinase superfamily.	0.465
B7P0R2_IXOSC	B7PKS1_IXOSC	B7P0R2	B7PKS1	C. elegans sem-5, putative.	Receptor protein-tyrosine kinase.	0.865
B7P0R2_IXOSC	B7PN76_IXOSC	B7P0R2	B7PN76	C. elegans sem-5, putative.	Tyrosine kinase, putative (Fragment).	0.458
B7P0R2_IXOSC	B7PP73_IXOSC	B7P0R2	B7PP73	C. elegans sem-5, putative.	Mitogen-activated protein kinase kinase MKK4, putative (Fragment); Belongs to the protein kinase superfamily.	0.635
B7P0R2_IXOSC	B7PQ59_IXOSC	B7P0R2	B7PQ59	C. elegans sem-5, putative.	Ras GTP exchange factor, son of sevenless, putative (Fragment).	0.999
B7P0R2_IXOSC	B7Q1P4_IXOSC	B7P0R2	B7Q1P4	C. elegans sem-5, putative.	Shc transforming protein, putative (Fragment).	0.983
B7P0R2_IXOSC	B7Q2R0_IXOSC	B7P0R2	B7Q2R0	C. elegans sem-5, putative.	Adaptor protein Crk, putative (Fragment).	0.883
B7P0R2_IXOSC	B7Q6K8_IXOSC	B7P0R2	B7Q6K8	C. elegans sem-5, putative.	Phosphatidylinositol 3-kinase catalytic subunit, putative; Belongs to the PI3/PI4-kinase family.	0.682
B7P0R2_IXOSC	B7Q903_IXOSC	B7P0R2	B7Q903	C. elegans sem-5, putative.	Pole hole family protein.	0.729
B7P0R2_IXOSC	B7QJF5_IXOSC	B7P0R2	B7QJF5	C. elegans sem-5, putative.	Phosphatidylinositol 3-kinase catalytic subunit, putative (Fragment); Belongs to the PI3/PI4-kinase family.	0.682
B7P0R2_IXOSC	B7QJT0_IXOSC	B7P0R2	B7QJT0	C. elegans sem-5, putative.	Rho guanine nucleotide exchange factor, putative (Fragment).	0.934
B7P5V5_IXOSC	B7P0R2_IXOSC	B7P5V5	B7P0R2	RAC serine/threonine kinase, putative; Belongs to the protein kinase superfamily.	C. elegans sem-5, putative.	0.465
B7P5V5_IXOSC	B7P9S6_IXOSC	B7P5V5	B7P9S6	RAC serine/threonine kinase, putative; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.722
B7P5V5_IXOSC	B7PEL7_IXOSC	B7P5V5	B7PEL7	RAC serine/threonine kinase, putative; Belongs to the protein kinase superfamily.	Signal transduction protein lnk-realted, putative.	0.416
B7P5V5_IXOSC	B7PHG1_IXOSC	B7P5V5	B7PHG1	RAC serine/threonine kinase, putative; Belongs to the protein kinase superfamily.	cAMP-dependent protein kinase catalytic subunit, putative; Belongs to the protein kinase superfamily.	0.908
B7P5V5_IXOSC	B7PP73_IXOSC	B7P5V5	B7PP73	RAC serine/threonine kinase, putative; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase MKK4, putative (Fragment); Belongs to the protein kinase superfamily.	0.524
B7P5V5_IXOSC	B7PTK2_IXOSC	B7P5V5	B7PTK2	RAC serine/threonine kinase, putative; Belongs to the protein kinase superfamily.	Eukaryotic translation initiation factor 4E binding protein, putative.	0.456