(30 nodes) Synaptic vesicle endocytosis network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7P1P7_IXOSC	COesterase domain-containing protein. (51 aa)
	B7P1P8_IXOSC	Acetylcholinesterase 2 precursor, putative. (63 aa)
	B7P2F7_IXOSC	RAS-related protein, putative (Fragment). (175 aa)
	B7P4A7_IXOSC	ADP-ribosylation factor, ARF, putative; Belongs to the small GTPase superfamily. Arf family. (180 aa)
	B7P4H4_IXOSC	PID domain-containing protein. (445 aa)
	B7P751_IXOSC	Uncharacterized protein. (297 aa)
	B7P797_IXOSC	ADP ribosylation factor 79F, putative; Belongs to the small GTPase superfamily. Arf family. (180 aa)
	B7P9U3_IXOSC	Transmembrane protein cmp44E, putative (Fragment). (806 aa)
	B7PDK3_IXOSC	Cuticular protein, putative (Fragment). (166 aa)
	B7PH72_IXOSC	Uncharacterized protein. (813 aa)
	B7PK64_IXOSC	Synaptojanin, putative. (921 aa)
	B7PM12_IXOSC	Dynamin, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (832 aa)
	B7PMB5_IXOSC	Phosphatidylinositol-binding clathrin assembly protein, putative. (821 aa)
	B7PQM0_IXOSC	Adaptor complexes medium subunit family protein. (851 aa)
	B7PUL0_IXOSC	MFS domain-containing protein. (219 aa)
	B7PVP6_IXOSC	Rho/RAC guanine nucleotide exchange factor, putative. (599 aa)
	B7PVP7_IXOSC	Intersectin, putative. (519 aa)
	B7Q054_IXOSC	Lysophosphatidic acid acyltransferase endophilin, putative. (350 aa)
	B7Q0Z0_IXOSC	GTP-binding ADP-ribosylation factor ARF6, putative; Belongs to the small GTPase superfamily. Arf family. (201 aa)
	B7Q647_IXOSC	Neuroligin, putative. (159 aa)
	B7Q682_IXOSC	Uncharacterized protein. (554 aa)
	B7Q6I0_IXOSC	Chr10 synaptotagmin, putative. (356 aa)
	B7QCW2_IXOSC	ADP-ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
	B7QCW3_IXOSC	Calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinase, putative. (505 aa)
	B7QGA4_IXOSC	COesterase domain-containing protein. (543 aa)
	B7QGJ2_IXOSC	Uncharacterized protein. (2382 aa)
	B7QK59_IXOSC	Uncharacterized protein. (183 aa)
	B7QKY8_IXOSC	Acetylcholinesterase 2, putative. (59 aa)
	B7QLI1_IXOSC	Vacuolar sorting protein, putative (Fragment). (738 aa)
	B7QME3_IXOSC	Intersectin, putative. (165 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P1P7_IXOSC	B7Q682_IXOSC	B7P1P7	B7Q682	COesterase domain-containing protein.	Uncharacterized protein.	0.630
B7P1P7_IXOSC	B7QCW3_IXOSC	B7P1P7	B7QCW3	COesterase domain-containing protein.	Calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinase, putative.	0.497
B7P1P8_IXOSC	B7Q682_IXOSC	B7P1P8	B7Q682	Acetylcholinesterase 2 precursor, putative.	Uncharacterized protein.	0.630
B7P1P8_IXOSC	B7QCW3_IXOSC	B7P1P8	B7QCW3	Acetylcholinesterase 2 precursor, putative.	Calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinase, putative.	0.497
B7P2F7_IXOSC	B7P4A7_IXOSC	B7P2F7	B7P4A7	RAS-related protein, putative (Fragment).	ADP-ribosylation factor, ARF, putative; Belongs to the small GTPase superfamily. Arf family.	0.437
B7P2F7_IXOSC	B7PM12_IXOSC	B7P2F7	B7PM12	RAS-related protein, putative (Fragment).	Dynamin, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.706
B7P2F7_IXOSC	B7Q054_IXOSC	B7P2F7	B7Q054	RAS-related protein, putative (Fragment).	Lysophosphatidic acid acyltransferase endophilin, putative.	0.572
B7P2F7_IXOSC	B7QCW2_IXOSC	B7P2F7	B7QCW2	RAS-related protein, putative (Fragment).	ADP-ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.	0.437
B7P2F7_IXOSC	B7QGJ2_IXOSC	B7P2F7	B7QGJ2	RAS-related protein, putative (Fragment).	Uncharacterized protein.	0.594
B7P2F7_IXOSC	B7QLI1_IXOSC	B7P2F7	B7QLI1	RAS-related protein, putative (Fragment).	Vacuolar sorting protein, putative (Fragment).	0.661
B7P4A7_IXOSC	B7P2F7_IXOSC	B7P4A7	B7P2F7	ADP-ribosylation factor, ARF, putative; Belongs to the small GTPase superfamily. Arf family.	RAS-related protein, putative (Fragment).	0.437
B7P4A7_IXOSC	B7PM12_IXOSC	B7P4A7	B7PM12	ADP-ribosylation factor, ARF, putative; Belongs to the small GTPase superfamily. Arf family.	Dynamin, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.432
B7P4A7_IXOSC	B7PVP6_IXOSC	B7P4A7	B7PVP6	ADP-ribosylation factor, ARF, putative; Belongs to the small GTPase superfamily. Arf family.	Rho/RAC guanine nucleotide exchange factor, putative.	0.779
B7P4A7_IXOSC	B7PVP7_IXOSC	B7P4A7	B7PVP7	ADP-ribosylation factor, ARF, putative; Belongs to the small GTPase superfamily. Arf family.	Intersectin, putative.	0.779
B7P4A7_IXOSC	B7QGJ2_IXOSC	B7P4A7	B7QGJ2	ADP-ribosylation factor, ARF, putative; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.781
B7P4H4_IXOSC	B7P751_IXOSC	B7P4H4	B7P751	PID domain-containing protein.	Uncharacterized protein.	0.618
B7P4H4_IXOSC	B7PM12_IXOSC	B7P4H4	B7PM12	PID domain-containing protein.	Dynamin, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.435
B7P4H4_IXOSC	B7PMB5_IXOSC	B7P4H4	B7PMB5	PID domain-containing protein.	Phosphatidylinositol-binding clathrin assembly protein, putative.	0.733
B7P4H4_IXOSC	B7PQM0_IXOSC	B7P4H4	B7PQM0	PID domain-containing protein.	Adaptor complexes medium subunit family protein.	0.838
B7P4H4_IXOSC	B7PVP6_IXOSC	B7P4H4	B7PVP6	PID domain-containing protein.	Rho/RAC guanine nucleotide exchange factor, putative.	0.962