(23 nodes) Growth factor receptor binding network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7P466_IXOSC	Serine-threonine protein kinase, plant-type, putative. (788 aa)
	B7P5U8_IXOSC	Ras GTPase-activating protein, putative. (755 aa)
	B7Q8B7_IXOSC	Uncharacterized protein. (276 aa)
	B7Q6M8_IXOSC	VEGF183 protein, putative; Belongs to the PDGF/VEGF growth factor family. (308 aa)
	B7Q6G3_IXOSC	Gremlin-1, putative. (170 aa)
	B7Q1P4_IXOSC	Shc transforming protein, putative (Fragment). (461 aa)
	B7QJ30_IXOSC	ATP binding protein, putative. (238 aa)
	B7QMP5_IXOSC	Suc1-associated neurotrophic factor target, putative. (251 aa)
	B7PF30_IXOSC	Argos, putative. (105 aa)
	B7PDA7_IXOSC	Placenta growth factor, putative; Belongs to the PDGF/VEGF growth factor family. (149 aa)
	B7PDA6_IXOSC	PDGF_2 domain-containing protein. (77 aa)
	B7PXH9_IXOSC	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (153 aa)
	B7PTW6_IXOSC	Uncharacterized protein. (529 aa)
	B7PTQ5_IXOSC	Cyclin T-dependent kinase CDK9, putative; Belongs to the protein kinase superfamily. (454 aa)
	B7PSQ9_IXOSC	Secreted protein, putative (Fragment). (252 aa)
	B7Q9Y5_IXOSC	Sorting nexin, putative. (369 aa)
	B7PSQ2_IXOSC	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (176 aa)
	B7P9D6_IXOSC	Protein spitz, putative (Fragment). (165 aa)
	B7PRA9_IXOSC	Stumps family protein. (371 aa)
	B7PP85_IXOSC	Secreted protein, putative. (285 aa)
	B7PP82_IXOSC	Secreted protein, putative (Fragment). (234 aa)
	B7PFZ8_IXOSC	Kekkon1 (Kek1), putative. (544 aa)
	B7P0R2_IXOSC	C. elegans sem-5, putative. (211 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P0R2_IXOSC	B7P5U8_IXOSC	B7P0R2	B7P5U8	C. elegans sem-5, putative.	Ras GTPase-activating protein, putative.	0.404
B7P0R2_IXOSC	B7PXH9_IXOSC	B7P0R2	B7PXH9	C. elegans sem-5, putative.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.753
B7P0R2_IXOSC	B7Q1P4_IXOSC	B7P0R2	B7Q1P4	C. elegans sem-5, putative.	Shc transforming protein, putative (Fragment).	0.983
B7P0R2_IXOSC	B7QMP5_IXOSC	B7P0R2	B7QMP5	C. elegans sem-5, putative.	Suc1-associated neurotrophic factor target, putative.	0.929
B7P5U8_IXOSC	B7P0R2_IXOSC	B7P5U8	B7P0R2	Ras GTPase-activating protein, putative.	C. elegans sem-5, putative.	0.404
B7PXH9_IXOSC	B7P0R2_IXOSC	B7PXH9	B7P0R2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	C. elegans sem-5, putative.	0.753
B7PXH9_IXOSC	B7Q1P4_IXOSC	B7PXH9	B7Q1P4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Shc transforming protein, putative (Fragment).	0.530
B7PXH9_IXOSC	B7QMP5_IXOSC	B7PXH9	B7QMP5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Suc1-associated neurotrophic factor target, putative.	0.543
B7Q1P4_IXOSC	B7P0R2_IXOSC	B7Q1P4	B7P0R2	Shc transforming protein, putative (Fragment).	C. elegans sem-5, putative.	0.983
B7Q1P4_IXOSC	B7PXH9_IXOSC	B7Q1P4	B7PXH9	Shc transforming protein, putative (Fragment).	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.530
B7QMP5_IXOSC	B7P0R2_IXOSC	B7QMP5	B7P0R2	Suc1-associated neurotrophic factor target, putative.	C. elegans sem-5, putative.	0.929
B7QMP5_IXOSC	B7PXH9_IXOSC	B7QMP5	B7PXH9	Suc1-associated neurotrophic factor target, putative.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.543