(26 nodes) Multivesicular body sorting pathway network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7PJD7_IXOSC	Uncharacterized protein. (92 aa)
	B7P999_IXOSC	Signal transducing adapter molecule, putative. (392 aa)
	B7PCX5_IXOSC	Hepatocyte growth factor-regulated tyrosine kinase substrate, putative. (392 aa)
	B7PDY7_IXOSC	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (245 aa)
	B7QDS8_IXOSC	Uncharacterized protein. (117 aa)
	B7QCS0_IXOSC	Vacuolar protein-sorting protein, putative. (356 aa)
	B7Q4B8_IXOSC	Vacuolar sorting protein VPS24, putative. (177 aa)
	B7Q451_IXOSC	Vps20associated 1 (S. cerevisiae) family protein. (169 aa)
	B7QLY9_IXOSC	Vacuolar protein-sorting protein, putative. (221 aa)
	B7QLV2_IXOSC	Vacuolar fusion protein mon1 a family protein. (91 aa)
	B7QKA5_IXOSC	Vacuolar assembly/sorting protein DID2, putative (Fragment). (205 aa)
	B7QFF0_IXOSC	Vacuolar assembly/sorting protein DID2, putative. (198 aa)
	B7Q2R3_IXOSC	Glucose de-repression and pre-vacuolar sorting protein, putative (Fragment). (159 aa)
	B7PZ70_IXOSC	RAS-related protein, putative. (126 aa)
	B7PX77_IXOSC	Protein FAM45B family protein. (124 aa)
	B7PV12_IXOSC	Membrane protein, putative. (179 aa)
	B7PT80_IXOSC	Spindle pole body protein, putative. (312 aa)
	B7PSW5_IXOSC	Programmed cell death 6-interacting protein, putative. (866 aa)
	B7PSK1_IXOSC	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (224 aa)
	B7PRV9_IXOSC	Vacuolar assembly/sorting protein DID4, putative. (212 aa)
	B7PN70_IXOSC	Charged multivesicular body protein, putative. (417 aa)
	B7P7Q6_IXOSC	Vacuolar protein-sorting-associated protein, putative. (175 aa)
	B7P2F7_IXOSC	RAS-related protein, putative (Fragment). (175 aa)
	B7PE61_IXOSC	Vacuolar assembly/sorting protein DID4, putative. (228 aa)
	B7PK89_IXOSC	Uncharacterized protein. (160 aa)
	B7PGD2_IXOSC	Tyrosine protein phosphatase non-receptor type, putative. (1400 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P2F7_IXOSC	B7P7Q6_IXOSC	B7P2F7	B7P7Q6	RAS-related protein, putative (Fragment).	Vacuolar protein-sorting-associated protein, putative.	0.548
B7P2F7_IXOSC	B7P999_IXOSC	B7P2F7	B7P999	RAS-related protein, putative (Fragment).	Signal transducing adapter molecule, putative.	0.408
B7P2F7_IXOSC	B7PCX5_IXOSC	B7P2F7	B7PCX5	RAS-related protein, putative (Fragment).	Hepatocyte growth factor-regulated tyrosine kinase substrate, putative.	0.600
B7P2F7_IXOSC	B7PZ70_IXOSC	B7P2F7	B7PZ70	RAS-related protein, putative (Fragment).	RAS-related protein, putative.	0.412
B7P2F7_IXOSC	B7QLV2_IXOSC	B7P2F7	B7QLV2	RAS-related protein, putative (Fragment).	Vacuolar fusion protein mon1 a family protein.	0.695
B7P7Q6_IXOSC	B7P2F7_IXOSC	B7P7Q6	B7P2F7	Vacuolar protein-sorting-associated protein, putative.	RAS-related protein, putative (Fragment).	0.548
B7P7Q6_IXOSC	B7P999_IXOSC	B7P7Q6	B7P999	Vacuolar protein-sorting-associated protein, putative.	Signal transducing adapter molecule, putative.	0.930
B7P7Q6_IXOSC	B7PCX5_IXOSC	B7P7Q6	B7PCX5	Vacuolar protein-sorting-associated protein, putative.	Hepatocyte growth factor-regulated tyrosine kinase substrate, putative.	0.880
B7P7Q6_IXOSC	B7PDY7_IXOSC	B7P7Q6	B7PDY7	Vacuolar protein-sorting-associated protein, putative.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.999
B7P7Q6_IXOSC	B7PE61_IXOSC	B7P7Q6	B7PE61	Vacuolar protein-sorting-associated protein, putative.	Vacuolar assembly/sorting protein DID4, putative.	0.958
B7P7Q6_IXOSC	B7PGD2_IXOSC	B7P7Q6	B7PGD2	Vacuolar protein-sorting-associated protein, putative.	Tyrosine protein phosphatase non-receptor type, putative.	0.422
B7P7Q6_IXOSC	B7PJD7_IXOSC	B7P7Q6	B7PJD7	Vacuolar protein-sorting-associated protein, putative.	Uncharacterized protein.	0.998
B7P7Q6_IXOSC	B7PK89_IXOSC	B7P7Q6	B7PK89	Vacuolar protein-sorting-associated protein, putative.	Uncharacterized protein.	0.482
B7P7Q6_IXOSC	B7PN70_IXOSC	B7P7Q6	B7PN70	Vacuolar protein-sorting-associated protein, putative.	Charged multivesicular body protein, putative.	0.942
B7P7Q6_IXOSC	B7PRV9_IXOSC	B7P7Q6	B7PRV9	Vacuolar protein-sorting-associated protein, putative.	Vacuolar assembly/sorting protein DID4, putative.	0.855
B7P7Q6_IXOSC	B7PSK1_IXOSC	B7P7Q6	B7PSK1	Vacuolar protein-sorting-associated protein, putative.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.990
B7P7Q6_IXOSC	B7PSW5_IXOSC	B7P7Q6	B7PSW5	Vacuolar protein-sorting-associated protein, putative.	Programmed cell death 6-interacting protein, putative.	0.632
B7P7Q6_IXOSC	B7PT80_IXOSC	B7P7Q6	B7PT80	Vacuolar protein-sorting-associated protein, putative.	Spindle pole body protein, putative.	0.662
B7P7Q6_IXOSC	B7Q2R3_IXOSC	B7P7Q6	B7Q2R3	Vacuolar protein-sorting-associated protein, putative.	Glucose de-repression and pre-vacuolar sorting protein, putative (Fragment).	0.967
B7P7Q6_IXOSC	B7Q451_IXOSC	B7P7Q6	B7Q451	Vacuolar protein-sorting-associated protein, putative.	Vps20associated 1 (S. cerevisiae) family protein.	0.482