(41 nodes) Malpighian tubule development network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7PIH8_IXOSC	Chitin synthase, putative. (811 aa)
	B7QIT4_IXOSC	Pre-mRNA splicing factor Syf1, putative. (850 aa)
	B7QIG3_IXOSC	Electron transfer flavoprotein, alpha subunit, putative (Fragment). (341 aa)
	B7QEY1_IXOSC	Helix-loop-helix protein, putative. (215 aa)
	B7QDS2_IXOSC	Matricellular protein osteonectin/SPARC/BM-40, putative. (242 aa)
	B7QD53_IXOSC	Homeobox protein cut-like. (1388 aa)
	B7QBD4_IXOSC	Immunodeficiency virus type I enhancer binding protein, putative. (803 aa)
	B7Q836_IXOSC	Crooked neck protein, putative. (583 aa)
	B7Q6M8_IXOSC	VEGF183 protein, putative; Belongs to the PDGF/VEGF growth factor family. (308 aa)
	B7Q5U3_IXOSC	SGT1 protein, putative. (640 aa)
	B7Q4H9_IXOSC	PID domain-containing protein. (312 aa)
	B7Q194_IXOSC	BHLH domain-containing protein. (115 aa)
	B7PZD3_IXOSC	Musculin, putative. (206 aa)
	B7PYC7_IXOSC	Fibropellin-1, putative (Fragment). (665 aa)
	B7PV81_IXOSC	Leucine rich domain-containing protein, putative (Fragment). (1327 aa)
	B7PV35_IXOSC	MH2 domain-containing protein. (207 aa)
	B7PTV5_IXOSC	Epithelial cell transforming 2, putative. (119 aa)
	B7PR50_IXOSC	Guanine nucleotide releasing factor, putative (Fragment). (466 aa)
	B7PLV7_IXOSC	Neuronal pas domain protein, putative (Fragment). (283 aa)
	B7PLV6_IXOSC	Neuronal pas domain protein, putative. (469 aa)
	B7PKS1_IXOSC	Receptor protein-tyrosine kinase. (1083 aa)
	B7PKK5_IXOSC	GTPase Rho, putative. (82 aa)
	B7PII2_IXOSC	Uncharacterized protein. (477 aa)
	B7PII1_IXOSC	Chitin synthase, putative. (1562 aa)
	B7PH66_IXOSC	GTPase Rho, putative. (192 aa)
	B7PH65_IXOSC	GTPase Rho, putative (Fragment). (205 aa)
	B7PH64_IXOSC	Cdc42 protein, putative. (201 aa)
	B7PCF8_IXOSC	Short gastrulation protein, putative. (123 aa)
	B7PCF7_IXOSC	Chordin, putative. (712 aa)
	B7PAU9_IXOSC	BHLH domain-containing protein. (171 aa)
	B7P9N2_IXOSC	Dock-1, putative (Fragment); Belongs to the DOCK family. (1613 aa)
	B7P8X6_IXOSC	Cdc42 protein, putative (Fragment). (238 aa)
	B7P8Q4_IXOSC	T-box transcription factor, putative (Fragment). (159 aa)
	B7P6G3_IXOSC	Uncharacterized protein. (87 aa)
	B7P561_IXOSC	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (465 aa)
	B7P3M5_IXOSC	Uncharacterized protein. (915 aa)
	B7P2R5_IXOSC	Coup transcription factor, putative. (226 aa)
	B7P2R4_IXOSC	Coup transcription factor, putative. (236 aa)
	B7P1W0_IXOSC	Uncharacterized protein. (462 aa)
	B7P1J6_IXOSC	GTPase Rho, putative. (228 aa)
	B7P0X0_IXOSC	Ets2, putative. (609 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P0X0_IXOSC	B7QDS2_IXOSC	B7P0X0	B7QDS2	Ets2, putative.	Matricellular protein osteonectin/SPARC/BM-40, putative.	0.407
B7P1J6_IXOSC	B7P3M5_IXOSC	B7P1J6	B7P3M5	GTPase Rho, putative.	Uncharacterized protein.	0.467
B7P1J6_IXOSC	B7P6G3_IXOSC	B7P1J6	B7P6G3	GTPase Rho, putative.	Uncharacterized protein.	0.513
B7P1J6_IXOSC	B7P9N2_IXOSC	B7P1J6	B7P9N2	GTPase Rho, putative.	Dock-1, putative (Fragment); Belongs to the DOCK family.	0.579
B7P1J6_IXOSC	B7PR50_IXOSC	B7P1J6	B7PR50	GTPase Rho, putative.	Guanine nucleotide releasing factor, putative (Fragment).	0.553
B7P1J6_IXOSC	B7PTV5_IXOSC	B7P1J6	B7PTV5	GTPase Rho, putative.	Epithelial cell transforming 2, putative.	0.513
B7P3M5_IXOSC	B7P1J6_IXOSC	B7P3M5	B7P1J6	Uncharacterized protein.	GTPase Rho, putative.	0.467
B7P3M5_IXOSC	B7P8X6_IXOSC	B7P3M5	B7P8X6	Uncharacterized protein.	Cdc42 protein, putative (Fragment).	0.467
B7P3M5_IXOSC	B7PH64_IXOSC	B7P3M5	B7PH64	Uncharacterized protein.	Cdc42 protein, putative.	0.467
B7P3M5_IXOSC	B7PH65_IXOSC	B7P3M5	B7PH65	Uncharacterized protein.	GTPase Rho, putative (Fragment).	0.467
B7P3M5_IXOSC	B7PH66_IXOSC	B7P3M5	B7PH66	Uncharacterized protein.	GTPase Rho, putative.	0.467
B7P3M5_IXOSC	B7PKK5_IXOSC	B7P3M5	B7PKK5	Uncharacterized protein.	GTPase Rho, putative.	0.467
B7P3M5_IXOSC	B7PYC7_IXOSC	B7P3M5	B7PYC7	Uncharacterized protein.	Fibropellin-1, putative (Fragment).	0.673
B7P3M5_IXOSC	B7Q4H9_IXOSC	B7P3M5	B7Q4H9	Uncharacterized protein.	PID domain-containing protein.	0.637
B7P561_IXOSC	B7PV35_IXOSC	B7P561	B7PV35	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	MH2 domain-containing protein.	0.686
B7P561_IXOSC	B7QBD4_IXOSC	B7P561	B7QBD4	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Immunodeficiency virus type I enhancer binding protein, putative.	0.626
B7P6G3_IXOSC	B7P1J6_IXOSC	B7P6G3	B7P1J6	Uncharacterized protein.	GTPase Rho, putative.	0.513
B7P6G3_IXOSC	B7P8X6_IXOSC	B7P6G3	B7P8X6	Uncharacterized protein.	Cdc42 protein, putative (Fragment).	0.513
B7P6G3_IXOSC	B7PH64_IXOSC	B7P6G3	B7PH64	Uncharacterized protein.	Cdc42 protein, putative.	0.513
B7P6G3_IXOSC	B7PH65_IXOSC	B7P6G3	B7PH65	Uncharacterized protein.	GTPase Rho, putative (Fragment).	0.513