(23 nodes) Site of DNA damage network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7QCD1_IXOSC	DNA damage-binding protein, putative. (260 aa)
	B7QE59_IXOSC	WD-repeat protein, putative. (489 aa)
	B7PQ39_IXOSC	ADP-ribosylglycohydrolase, putative. (246 aa)
	B7PNL2_IXOSC	3-5 exonuclease, putative. (587 aa)
	B7PNK5_IXOSC	SMC proteins Flexible Hinge Domaincontaining protein. (796 aa)
	B7PIM4_IXOSC	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (687 aa)
	B7PIF3_IXOSC	DNA repair protein xp-E, putative. (1148 aa)
	B7PHU5_IXOSC	DNA damage-binding protein, putative. (440 aa)
	B7PEW4_IXOSC	Histone H2A; Belongs to the histone H2A family. (99 aa)
	B7PEV9_IXOSC	RING-type domain-containing protein. (206 aa)
	B7PDB4_IXOSC	Zinc finger, C3HC4 type (RING finger) domaincontaining protein. (614 aa)
	B7PC76_IXOSC	Uncharacterized protein. (107 aa)
	B7P4T3_IXOSC	FHA domaincontaining protein. (314 aa)
	B7P3D1_IXOSC	Tpr and ank domain-containing protein, putative. (1169 aa)
	B7P366_IXOSC	Mitotic and DNA damage checkpoint protein hus1, putative. (283 aa)
	B7P1A4_IXOSC	zf-CCHH domain-containing protein. (503 aa)
	B7QGR1_IXOSC	Paramyosin, putative. (1024 aa)
	B7QI10_IXOSC	DNA polymerase eta, putative. (727 aa)
	B7QN06_IXOSC	Cullin, putative (Fragment); Belongs to the cullin family. (787 aa)
	B7QNS9_IXOSC	Uncharacterized protein. (143 aa)
	B7QNT4_IXOSC	Structural maintenance of chromosomes flexible hinge domaincontaining protein 1, putative. (230 aa)
	B7PQ97_IXOSC	DNA excision repair protein ERCC-6, putative (Fragment). (982 aa)
	B7PQ41_IXOSC	Adprhl2 protein, putative. (105 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P1A4_IXOSC	B7PC76_IXOSC	B7P1A4	B7PC76	zf-CCHH domain-containing protein.	Uncharacterized protein.	0.876
B7P1A4_IXOSC	B7PIM4_IXOSC	B7P1A4	B7PIM4	zf-CCHH domain-containing protein.	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.	0.876
B7P366_IXOSC	B7PC76_IXOSC	B7P366	B7PC76	Mitotic and DNA damage checkpoint protein hus1, putative.	Uncharacterized protein.	0.514
B7P366_IXOSC	B7PIM4_IXOSC	B7P366	B7PIM4	Mitotic and DNA damage checkpoint protein hus1, putative.	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.	0.514
B7P366_IXOSC	B7PQ97_IXOSC	B7P366	B7PQ97	Mitotic and DNA damage checkpoint protein hus1, putative.	DNA excision repair protein ERCC-6, putative (Fragment).	0.428
B7P3D1_IXOSC	B7P4T3_IXOSC	B7P3D1	B7P4T3	Tpr and ank domain-containing protein, putative.	FHA domaincontaining protein.	0.437
B7P4T3_IXOSC	B7P3D1_IXOSC	B7P4T3	B7P3D1	FHA domaincontaining protein.	Tpr and ank domain-containing protein, putative.	0.437
B7P4T3_IXOSC	B7PC76_IXOSC	B7P4T3	B7PC76	FHA domaincontaining protein.	Uncharacterized protein.	0.474
B7P4T3_IXOSC	B7PEV9_IXOSC	B7P4T3	B7PEV9	FHA domaincontaining protein.	RING-type domain-containing protein.	0.849
B7P4T3_IXOSC	B7PIM4_IXOSC	B7P4T3	B7PIM4	FHA domaincontaining protein.	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.	0.474
B7PC76_IXOSC	B7P1A4_IXOSC	B7PC76	B7P1A4	Uncharacterized protein.	zf-CCHH domain-containing protein.	0.876
B7PC76_IXOSC	B7P366_IXOSC	B7PC76	B7P366	Uncharacterized protein.	Mitotic and DNA damage checkpoint protein hus1, putative.	0.514
B7PC76_IXOSC	B7P4T3_IXOSC	B7PC76	B7P4T3	Uncharacterized protein.	FHA domaincontaining protein.	0.474
B7PC76_IXOSC	B7PEV9_IXOSC	B7PC76	B7PEV9	Uncharacterized protein.	RING-type domain-containing protein.	0.457
B7PC76_IXOSC	B7PQ97_IXOSC	B7PC76	B7PQ97	Uncharacterized protein.	DNA excision repair protein ERCC-6, putative (Fragment).	0.426
B7PC76_IXOSC	B7QGR1_IXOSC	B7PC76	B7QGR1	Uncharacterized protein.	Paramyosin, putative.	0.438
B7PC76_IXOSC	B7QI10_IXOSC	B7PC76	B7QI10	Uncharacterized protein.	DNA polymerase eta, putative.	0.406
B7PDB4_IXOSC	B7PEV9_IXOSC	B7PDB4	B7PEV9	Zinc finger, C3HC4 type (RING finger) domaincontaining protein.	RING-type domain-containing protein.	0.536
B7PEV9_IXOSC	B7P4T3_IXOSC	B7PEV9	B7P4T3	RING-type domain-containing protein.	FHA domaincontaining protein.	0.849
B7PEV9_IXOSC	B7PC76_IXOSC	B7PEV9	B7PC76	RING-type domain-containing protein.	Uncharacterized protein.	0.457