(18 nodes) Axonal transport network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7P2V1_IXOSC	Huntington associated protein-1 domain, putative. (674 aa)
	B7P803_IXOSC	Liprin-alpha, putative. (1165 aa)
	B7P9A9_IXOSC	HyFMR1 protein, putative (Fragment). (506 aa)
	B7PGW3_IXOSC	Uncharacterized protein. (147 aa)
	B7PIZ2_IXOSC	ADP-ribosylation factor, putative (Fragment); Belongs to the small GTPase superfamily. Arf family. (151 aa)
	B7PMP6_IXOSC	AP-3 complex subunit delta-1, putative (Fragment). (925 aa)
	LIS1_IXOSC	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes. (411 aa)
	B7PUP5_IXOSC	Uncharacterized protein. (63 aa)
	B7PVL6_IXOSC	Jnk interacting protein, putative. (355 aa)
	B7Q207_IXOSC	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (717 aa)
	B7Q2M6_IXOSC	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (706 aa)
	B7Q609_IXOSC	Cytoplasmic dynein heavy chain, putative (Fragment). (2827 aa)
	B7Q7Z5_IXOSC	Dynein light chain, putative (Fragment). (115 aa)
	B7Q9F4_IXOSC	Dynactin subunit P25, putative. (185 aa)
	B7QAD6_IXOSC	Uncharacterized protein. (124 aa)
	B7QD00_IXOSC	Uncharacterized protein. (73 aa)
	B7QDE8_IXOSC	Actin, putative. (376 aa)
	B7QMT5_IXOSC	Uncharacterized protein. (159 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P803_IXOSC	B7PIZ2_IXOSC	B7P803	B7PIZ2	Liprin-alpha, putative.	ADP-ribosylation factor, putative (Fragment); Belongs to the small GTPase superfamily. Arf family.	0.481
B7PGW3_IXOSC	B7QMT5_IXOSC	B7PGW3	B7QMT5	Uncharacterized protein.	Uncharacterized protein.	0.855
B7PIZ2_IXOSC	B7P803_IXOSC	B7PIZ2	B7P803	ADP-ribosylation factor, putative (Fragment); Belongs to the small GTPase superfamily. Arf family.	Liprin-alpha, putative.	0.481
B7PUP5_IXOSC	B7Q609_IXOSC	B7PUP5	B7Q609	Uncharacterized protein.	Cytoplasmic dynein heavy chain, putative (Fragment).	0.450
B7PUP5_IXOSC	B7Q9F4_IXOSC	B7PUP5	B7Q9F4	Uncharacterized protein.	Dynactin subunit P25, putative.	0.978
B7PUP5_IXOSC	B7QAD6_IXOSC	B7PUP5	B7QAD6	Uncharacterized protein.	Uncharacterized protein.	0.540
B7PUP5_IXOSC	B7QDE8_IXOSC	B7PUP5	B7QDE8	Uncharacterized protein.	Actin, putative.	0.931
B7PUP5_IXOSC	LIS1_IXOSC	B7PUP5	B7PS00	Uncharacterized protein.	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes.	0.635
B7Q207_IXOSC	B7Q2M6_IXOSC	B7Q207	B7Q2M6	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.916
B7Q2M6_IXOSC	B7Q207_IXOSC	B7Q2M6	B7Q207	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.916
B7Q609_IXOSC	B7PUP5_IXOSC	B7Q609	B7PUP5	Cytoplasmic dynein heavy chain, putative (Fragment).	Uncharacterized protein.	0.450
B7Q609_IXOSC	B7Q7Z5_IXOSC	B7Q609	B7Q7Z5	Cytoplasmic dynein heavy chain, putative (Fragment).	Dynein light chain, putative (Fragment).	0.818
B7Q609_IXOSC	B7Q9F4_IXOSC	B7Q609	B7Q9F4	Cytoplasmic dynein heavy chain, putative (Fragment).	Dynactin subunit P25, putative.	0.504
B7Q609_IXOSC	B7QAD6_IXOSC	B7Q609	B7QAD6	Cytoplasmic dynein heavy chain, putative (Fragment).	Uncharacterized protein.	0.450
B7Q609_IXOSC	B7QDE8_IXOSC	B7Q609	B7QDE8	Cytoplasmic dynein heavy chain, putative (Fragment).	Actin, putative.	0.538
B7Q609_IXOSC	LIS1_IXOSC	B7Q609	B7PS00	Cytoplasmic dynein heavy chain, putative (Fragment).	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes.	0.771
B7Q7Z5_IXOSC	B7Q609_IXOSC	B7Q7Z5	B7Q609	Dynein light chain, putative (Fragment).	Cytoplasmic dynein heavy chain, putative (Fragment).	0.818
B7Q9F4_IXOSC	B7PUP5_IXOSC	B7Q9F4	B7PUP5	Dynactin subunit P25, putative.	Uncharacterized protein.	0.978
B7Q9F4_IXOSC	B7Q609_IXOSC	B7Q9F4	B7Q609	Dynactin subunit P25, putative.	Cytoplasmic dynein heavy chain, putative (Fragment).	0.504
B7Q9F4_IXOSC	B7QAD6_IXOSC	B7Q9F4	B7QAD6	Dynactin subunit P25, putative.	Uncharacterized protein.	0.978