(20 nodes) Ion channel regulator activity network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7Q321_IXOSC	Reticulon/nogo receptor, putative. (342 aa)
	B7PB19_IXOSC	SAM domain-containing protein. (410 aa)
	B7PDX0_IXOSC	COMM domain-containing protein, putative. (178 aa)
	B7PI92_IXOSC	Non-specific serine/threonine protein kinase. (420 aa)
	B7PKK8_IXOSC	Caveolin, putative (Fragment). (273 aa)
	B7PLW7_IXOSC	Calcium release-activated calcium channel protein, putative. (236 aa)
	B7PN38_IXOSC	Uncharacterized protein. (114 aa)
	B7PPZ3_IXOSC	Kv channel interacting protein 1 isoform 4 family protein. (286 aa)
	B7PRK6_IXOSC	Voltage-dependent calcium channel, putative. (297 aa)
	B7PSV5_IXOSC	Fucosyltransferase, putative. (365 aa)
	B7PTF3_IXOSC	Potassium channel beta, putative. (140 aa)
	B7PUZ4_IXOSC	Similar to THAP domaincontaining protein 9, putative. (422 aa)
	B7Q476_IXOSC	Potassium channel, putative. (117 aa)
	B7Q6C7_IXOSC	RAS related protein, putative (Fragment). (189 aa)
	B7Q8Q0_IXOSC	Ubiquitin protein ligase, putative. (972 aa)
	B7Q9I6_IXOSC	Mixed lineage kinase 4alpha, putative (Fragment). (340 aa)
	B7Q9I7_IXOSC	Serine/threonine protein kinase wnk 1,3,4, putative (Fragment). (114 aa)
	B7QA28_IXOSC	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	B7QC51_IXOSC	Ac2059 family protein. (151 aa)
	B7QI65_IXOSC	Uncharacterized protein. (100 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7PB19_IXOSC	B7PKK8_IXOSC	B7PB19	B7PKK8	SAM domain-containing protein.	Caveolin, putative (Fragment).	0.504
B7PB19_IXOSC	B7PLW7_IXOSC	B7PB19	B7PLW7	SAM domain-containing protein.	Calcium release-activated calcium channel protein, putative.	0.987
B7PI92_IXOSC	B7PN38_IXOSC	B7PI92	B7PN38	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.414
B7PI92_IXOSC	B7Q6C7_IXOSC	B7PI92	B7Q6C7	Non-specific serine/threonine protein kinase.	RAS related protein, putative (Fragment).	0.414
B7PI92_IXOSC	B7Q8Q0_IXOSC	B7PI92	B7Q8Q0	Non-specific serine/threonine protein kinase.	Ubiquitin protein ligase, putative.	0.531
B7PI92_IXOSC	B7QI65_IXOSC	B7PI92	B7QI65	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.414
B7PKK8_IXOSC	B7PB19_IXOSC	B7PKK8	B7PB19	Caveolin, putative (Fragment).	SAM domain-containing protein.	0.504
B7PKK8_IXOSC	B7QA28_IXOSC	B7PKK8	B7QA28	Caveolin, putative (Fragment).	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.972
B7PLW7_IXOSC	B7PB19_IXOSC	B7PLW7	B7PB19	Calcium release-activated calcium channel protein, putative.	SAM domain-containing protein.	0.987
B7PN38_IXOSC	B7PI92_IXOSC	B7PN38	B7PI92	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.414
B7Q6C7_IXOSC	B7PI92_IXOSC	B7Q6C7	B7PI92	RAS related protein, putative (Fragment).	Non-specific serine/threonine protein kinase.	0.414
B7Q8Q0_IXOSC	B7PI92_IXOSC	B7Q8Q0	B7PI92	Ubiquitin protein ligase, putative.	Non-specific serine/threonine protein kinase.	0.531
B7QA28_IXOSC	B7PKK8_IXOSC	B7QA28	B7PKK8	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin, putative (Fragment).	0.972
B7QI65_IXOSC	B7PI92_IXOSC	B7QI65	B7PI92	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.414