(31 nodes) Extrinsic component of plasma membrane network (Ixodes scapularis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7Q3T6_IXOSC	THO complex subunit, putative. (340 aa)
	B7PA70_IXOSC	Heterotrimeric G protein alpha subunit B, putative (Fragment). (314 aa)
	B7PMB5_IXOSC	Phosphatidylinositol-binding clathrin assembly protein, putative. (821 aa)
	B7PMQ0_IXOSC	Guanine nucleotide-binding protein G, putative. (376 aa)
	B7PP62_IXOSC	Guanine nucleotide-binding protein, putative. (306 aa)
	B7PPR8_IXOSC	Peptidylprolyl isomerase. (392 aa)
	B7PQ59_IXOSC	Ras GTP exchange factor, son of sevenless, putative (Fragment). (1034 aa)
	B7PTG5_IXOSC	PHB domain-containing protein. (308 aa)
	B7PVL8_IXOSC	Guanine nucleotide-binding protein G, putative (Fragment). (362 aa)
	B7Q0X8_IXOSC	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	B7Q1B7_IXOSC	GTP-binding protein alpha subunit, putative. (68 aa)
	B7Q2R0_IXOSC	Adaptor protein Crk, putative (Fragment). (310 aa)
	B7P9N2_IXOSC	Dock-1, putative (Fragment); Belongs to the DOCK family. (1613 aa)
	B7Q4C1_IXOSC	Kalirin, putative (Fragment). (1153 aa)
	B7QC38_IXOSC	Adenomatous polyposis coli protein, putative (Fragment). (208 aa)
	B7QE55_IXOSC	Alpha catenin, putative (Fragment). (917 aa)
	B7QEF7_IXOSC	Gb2-cadherin, putative; Cadherins are calcium-dependent cell adhesion proteins. (1518 aa)
	B7QEG1_IXOSC	Uncharacterized protein. (432 aa)
	B7QEG2_IXOSC	Cadherin domaincontaining protein. (421 aa)
	B7QGW7_IXOSC	Armadillo, putative (Fragment). (799 aa)
	B7QIE4_IXOSC	Vesicle coat complex COPI, beta' subunit, putative (Fragment). (325 aa)
	B7QKZ8_IXOSC	Guanine nucleotide-binding protein beta, putative. (133 aa)
	B7QNP2_IXOSC	Armadillo repeat protein, putative. (729 aa)
	B7P0Z1_IXOSC	GTP-binding protein (I) alpha subunit, (GNAI), putative. (54 aa)
	B7P225_IXOSC	G protein beta subunit, putative (Fragment). (170 aa)
	B7P654_IXOSC	PHB domain-containing protein. (295 aa)
	B7P6H1_IXOSC	FABD domain-containing protein. (766 aa)
	B7P6H2_IXOSC	Tyrosine-protein kinase. (464 aa)
	B7P6Q5_IXOSC	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1109 aa)
	B7P6S0_IXOSC	BTB domain-containing protein. (435 aa)
	B7P6V9_IXOSC	Uncharacterized protein. (233 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P0Z1_IXOSC	B7P225_IXOSC	B7P0Z1	B7P225	GTP-binding protein (I) alpha subunit, (GNAI), putative.	G protein beta subunit, putative (Fragment).	0.796
B7P0Z1_IXOSC	B7PA70_IXOSC	B7P0Z1	B7PA70	GTP-binding protein (I) alpha subunit, (GNAI), putative.	Heterotrimeric G protein alpha subunit B, putative (Fragment).	0.540
B7P0Z1_IXOSC	B7PMQ0_IXOSC	B7P0Z1	B7PMQ0	GTP-binding protein (I) alpha subunit, (GNAI), putative.	Guanine nucleotide-binding protein G, putative.	0.580
B7P0Z1_IXOSC	B7PP62_IXOSC	B7P0Z1	B7PP62	GTP-binding protein (I) alpha subunit, (GNAI), putative.	Guanine nucleotide-binding protein, putative.	0.698
B7P0Z1_IXOSC	B7PVL8_IXOSC	B7P0Z1	B7PVL8	GTP-binding protein (I) alpha subunit, (GNAI), putative.	Guanine nucleotide-binding protein G, putative (Fragment).	0.580
B7P0Z1_IXOSC	B7Q0X8_IXOSC	B7P0Z1	B7Q0X8	GTP-binding protein (I) alpha subunit, (GNAI), putative.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.613
B7P0Z1_IXOSC	B7Q1B7_IXOSC	B7P0Z1	B7Q1B7	GTP-binding protein (I) alpha subunit, (GNAI), putative.	GTP-binding protein alpha subunit, putative.	0.540
B7P0Z1_IXOSC	B7Q3T6_IXOSC	B7P0Z1	B7Q3T6	GTP-binding protein (I) alpha subunit, (GNAI), putative.	THO complex subunit, putative.	0.885
B7P0Z1_IXOSC	B7QIE4_IXOSC	B7P0Z1	B7QIE4	GTP-binding protein (I) alpha subunit, (GNAI), putative.	Vesicle coat complex COPI, beta' subunit, putative (Fragment).	0.891
B7P0Z1_IXOSC	B7QKZ8_IXOSC	B7P0Z1	B7QKZ8	GTP-binding protein (I) alpha subunit, (GNAI), putative.	Guanine nucleotide-binding protein beta, putative.	0.575
B7P225_IXOSC	B7P0Z1_IXOSC	B7P225	B7P0Z1	G protein beta subunit, putative (Fragment).	GTP-binding protein (I) alpha subunit, (GNAI), putative.	0.796
B7P225_IXOSC	B7PA70_IXOSC	B7P225	B7PA70	G protein beta subunit, putative (Fragment).	Heterotrimeric G protein alpha subunit B, putative (Fragment).	0.872
B7P225_IXOSC	B7PMQ0_IXOSC	B7P225	B7PMQ0	G protein beta subunit, putative (Fragment).	Guanine nucleotide-binding protein G, putative.	0.929
B7P225_IXOSC	B7PP62_IXOSC	B7P225	B7PP62	G protein beta subunit, putative (Fragment).	Guanine nucleotide-binding protein, putative.	0.916
B7P225_IXOSC	B7PVL8_IXOSC	B7P225	B7PVL8	G protein beta subunit, putative (Fragment).	Guanine nucleotide-binding protein G, putative (Fragment).	0.919
B7P225_IXOSC	B7Q0X8_IXOSC	B7P225	B7Q0X8	G protein beta subunit, putative (Fragment).	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.614
B7P225_IXOSC	B7Q1B7_IXOSC	B7P225	B7Q1B7	G protein beta subunit, putative (Fragment).	GTP-binding protein alpha subunit, putative.	0.835
B7P225_IXOSC	B7Q3T6_IXOSC	B7P225	B7Q3T6	G protein beta subunit, putative (Fragment).	THO complex subunit, putative.	0.699
B7P225_IXOSC	B7Q4C1_IXOSC	B7P225	B7Q4C1	G protein beta subunit, putative (Fragment).	Kalirin, putative (Fragment).	0.603
B7P225_IXOSC	B7QIE4_IXOSC	B7P225	B7QIE4	G protein beta subunit, putative (Fragment).	Vesicle coat complex COPI, beta' subunit, putative (Fragment).	0.671