(63 nodes) SH3-like domain superfamily network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7PNV7_IXOSC	Protein kinase C and casein kinase substrate in neurons protein, putative. (438 aa)
	B7P0R2_IXOSC	C. elegans sem-5, putative. (211 aa)
	B7P0S7_IXOSC	RAB GTPase-activating protein, putative (Fragment). (752 aa)
	B7P0V4_IXOSC	Cortactin, putative. (599 aa)
	B7P1B7_IXOSC	Variant sh3 domaincontaining protein. (617 aa)
	B7P1I5_IXOSC	Uncharacterized protein. (1521 aa)
	B7P1U8_IXOSC	Spectrin alpha chain, putative. (2368 aa)
	B7P264_IXOSC	Guanine nucleotide exchange factor, putative. (1373 aa)
	B7P2T3_IXOSC	Ankyrin repeat containing protein. (218 aa)
	B7P377_IXOSC	Lim and sh3 domain protein 1, lasp-1, putative. (272 aa)
	B7P4N9_IXOSC	SH3 domaincontaining protein. (84 aa)
	B7P4X9_IXOSC	Phosphoinositide phospholipase C. (1201 aa)
	B7P5U8_IXOSC	Ras GTPase-activating protein, putative. (755 aa)
	B7P6H0_IXOSC	Endophilin-B1, putative (Fragment). (337 aa)
	B7P6H2_IXOSC	Tyrosine-protein kinase. (464 aa)
	B7P7H6_IXOSC	SH3 domain-containing protein. (172 aa)
	B7P999_IXOSC	Signal transducing adapter molecule, putative. (392 aa)
	B7P9N2_IXOSC	Dock-1, putative (Fragment); Belongs to the DOCK family. (1613 aa)
	B7PAC0_IXOSC	Guanylate kinase, putative (Fragment). (444 aa)
	B7PBJ3_IXOSC	Uncharacterized protein. (407 aa)
	B7PBR2_IXOSC	Protein kinase, putative. (455 aa)
	B7PBX6_IXOSC	Tyrosine-protein kinase. (385 aa)
	B7PEH9_IXOSC	SH3 domain-containing protein. (639 aa)
	B7PFP2_IXOSC	Uncharacterized protein. (329 aa)
	B7PJF4_IXOSC	Discs large protein, putative. (1558 aa)
	B7PKY1_IXOSC	Docking protein, putative (Fragment). (831 aa)
	B7PL19_IXOSC	Tyrosine-protein kinase. (447 aa)
	B7PLE6_IXOSC	Bridging integrator, putative. (665 aa)
	B7PLY5_IXOSC	Uncharacterized protein. (459 aa)
	B7PN76_IXOSC	Tyrosine kinase, putative (Fragment). (455 aa)
	B7PS43_IXOSC	Uncharacterized protein. (325 aa)
	B7PSS5_IXOSC	Apoptosis stimulating of P53, putative. (720 aa)
	B7PTH6_IXOSC	Tight junction protein tama, putative; Belongs to the MAGUK family. (1421 aa)
	B7PUD5_IXOSC	BAR domaincontaining protein. (1461 aa)
	B7PVH4_IXOSC	Tyrosine-protein kinase. (467 aa)
	B7PVP6_IXOSC	Rho/RAC guanine nucleotide exchange factor, putative. (599 aa)
	B7PVP7_IXOSC	Intersectin, putative. (519 aa)
	B7PYH3_IXOSC	Variant sh3 domaincontaining protein. (535 aa)
	B7PZE7_IXOSC	Dbls big sister, dbs, putative (Fragment). (1009 aa)
	B7PZM2_IXOSC	Dcapl, putative. (402 aa)
	B7Q054_IXOSC	Lysophosphatidic acid acyltransferase endophilin, putative. (350 aa)
	B7Q1G0_IXOSC	Variant sh3 domaincontaining protein. (690 aa)
	B7Q2R0_IXOSC	Adaptor protein Crk, putative (Fragment). (310 aa)
	B7Q4U0_IXOSC	Development and differentiation-enhancing factor, ddef, putative. (318 aa)
	B7Q621_IXOSC	Voltage-gated calcium channel, putative (Fragment). (428 aa)
	B7Q8Z8_IXOSC	Uncharacterized protein. (377 aa)
	B7Q9T0_IXOSC	Collybistin, putative. (963 aa)
	B7Q9W0_IXOSC	Ubiquitin associated and SH3 domain-containing protein B, putative. (642 aa)
	B7QAU9_IXOSC	Maguk P55, putative; Belongs to the MAGUK family. (583 aa)
	B7QBP3_IXOSC	Tyrosine-protein kinase. (626 aa)
	B7QC67_IXOSC	Insulin receptor tyrosine kinase substrate, putative. (596 aa)
	B7QC81_IXOSC	Slit-robo Rho GTPase activating protein 1,3, putative. (740 aa)
	B7QCW3_IXOSC	Calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinase, putative. (505 aa)
	B7QEI4_IXOSC	Uncharacterized protein. (581 aa)
	B7QF00_IXOSC	Myosin, putative; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1026 aa)
	B7QF75_IXOSC	GTPase binding protein, putative. (479 aa)
	B7QGX4_IXOSC	CDC42 GTPase-activating protein, putative. (1561 aa)
	B7QIL2_IXOSC	Dreadlocks/dock, putative (Fragment). (372 aa)
	B7QJT0_IXOSC	Rho guanine nucleotide exchange factor, putative (Fragment). (572 aa)
	B7QKI9_IXOSC	Discs large protein, putative. (119 aa)
	B7QN08_IXOSC	SAM domain (Sterile alpha motif) domaincontaining protein. (773 aa)
	B7QNV0_IXOSC	Uncharacterized protein. (887 aa)
	B7QNY3_IXOSC	Rho GTPase-activating protein, putative. (790 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P0R2_IXOSC	B7P4X9_IXOSC	B7P0R2	B7P4X9	C. elegans sem-5, putative.	Phosphoinositide phospholipase C.	0.950
B7P0R2_IXOSC	B7P5U8_IXOSC	B7P0R2	B7P5U8	C. elegans sem-5, putative.	Ras GTPase-activating protein, putative.	0.404
B7P0R2_IXOSC	B7P6H0_IXOSC	B7P0R2	B7P6H0	C. elegans sem-5, putative.	Endophilin-B1, putative (Fragment).	0.465
B7P0R2_IXOSC	B7P6H2_IXOSC	B7P0R2	B7P6H2	C. elegans sem-5, putative.	Tyrosine-protein kinase.	0.655
B7P0R2_IXOSC	B7P7H6_IXOSC	B7P0R2	B7P7H6	C. elegans sem-5, putative.	SH3 domain-containing protein.	0.634
B7P0R2_IXOSC	B7P999_IXOSC	B7P0R2	B7P999	C. elegans sem-5, putative.	Signal transducing adapter molecule, putative.	0.723
B7P0R2_IXOSC	B7PBR2_IXOSC	B7P0R2	B7PBR2	C. elegans sem-5, putative.	Protein kinase, putative.	0.594
B7P0R2_IXOSC	B7PBX6_IXOSC	B7P0R2	B7PBX6	C. elegans sem-5, putative.	Tyrosine-protein kinase.	0.730
B7P0R2_IXOSC	B7PFP2_IXOSC	B7P0R2	B7PFP2	C. elegans sem-5, putative.	Uncharacterized protein.	0.482
B7P0R2_IXOSC	B7PKY1_IXOSC	B7P0R2	B7PKY1	C. elegans sem-5, putative.	Docking protein, putative (Fragment).	0.577
B7P0R2_IXOSC	B7PL19_IXOSC	B7P0R2	B7PL19	C. elegans sem-5, putative.	Tyrosine-protein kinase.	0.741
B7P0R2_IXOSC	B7PN76_IXOSC	B7P0R2	B7PN76	C. elegans sem-5, putative.	Tyrosine kinase, putative (Fragment).	0.458
B7P0R2_IXOSC	B7PS43_IXOSC	B7P0R2	B7PS43	C. elegans sem-5, putative.	Uncharacterized protein.	0.428
B7P0R2_IXOSC	B7PVH4_IXOSC	B7P0R2	B7PVH4	C. elegans sem-5, putative.	Tyrosine-protein kinase.	0.741
B7P0R2_IXOSC	B7PVP6_IXOSC	B7P0R2	B7PVP6	C. elegans sem-5, putative.	Rho/RAC guanine nucleotide exchange factor, putative.	0.926
B7P0R2_IXOSC	B7PVP7_IXOSC	B7P0R2	B7PVP7	C. elegans sem-5, putative.	Intersectin, putative.	0.926
B7P0R2_IXOSC	B7Q054_IXOSC	B7P0R2	B7Q054	C. elegans sem-5, putative.	Lysophosphatidic acid acyltransferase endophilin, putative.	0.626
B7P0R2_IXOSC	B7Q1G0_IXOSC	B7P0R2	B7Q1G0	C. elegans sem-5, putative.	Variant sh3 domaincontaining protein.	0.774
B7P0R2_IXOSC	B7Q2R0_IXOSC	B7P0R2	B7Q2R0	C. elegans sem-5, putative.	Adaptor protein Crk, putative (Fragment).	0.883
B7P0R2_IXOSC	B7QBP3_IXOSC	B7P0R2	B7QBP3	C. elegans sem-5, putative.	Tyrosine-protein kinase.	0.458