(22 nodes) mTORC1-mediated signalling network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7PTK2_IXOSC	Eukaryotic translation initiation factor 4E binding protein, putative. (125 aa)
	B7P9S6_IXOSC	Non-specific serine/threonine protein kinase. (344 aa)
	B7PB41_IXOSC	WD_REPEATS_REGION domain-containing protein. (324 aa)
	B7PE09_IXOSC	RNA-binding protein musashi, putative. (436 aa)
	B7PF10_IXOSC	RAS family protein, putative. (182 aa)
	B7PFU2_IXOSC	Uncharacterized protein. (398 aa)
	B7PII7_IXOSC	Uncharacterized protein. (78 aa)
	B7PLB2_IXOSC	Uncharacterized protein. (229 aa)
	B7PLB3_IXOSC	HEAT repeatcontaining protein. (995 aa)
	B7PLU8_IXOSC	40S ribosomal protein S6, putative (Fragment). (226 aa)
	B7PYD6_IXOSC	Protein disulfide isomerase, putative. (317 aa)
	B7PZB0_IXOSC	Protein C7orf59 family protein. (98 aa)
	B7Q018_IXOSC	Peptidylprolyl isomerase. (115 aa)
	B7Q5U4_IXOSC	MP1 adaptor interacting protein P14, putative. (125 aa)
	B7Q610_IXOSC	Ribosomal protein l7ae protein, putative. (728 aa)
	B7Q6G8_IXOSC	GTP-binding protein, putative. (316 aa)
	B7Q942_IXOSC	Translation initiation factor 4F, cap-binding subunit, putative; Belongs to the eukaryotic initiation factor 4E family. (210 aa)
	B7Q9E7_IXOSC	Eukaryotic elongation factor 2 kinase. (661 aa)
	B7QCU2_IXOSC	Small GTPase involved in nuclear protein import, putative. (379 aa)
	B7QGH3_IXOSC	Amino acid transporter, putative. (251 aa)
	B7QGQ3_IXOSC	143-3 isoform A isoform 2 family protein; Belongs to the 14-3-3 family. (101 aa)
	B7QH63_IXOSC	Uncharacterized protein. (162 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P9S6_IXOSC	B7PB41_IXOSC	B7P9S6	B7PB41	Non-specific serine/threonine protein kinase.	WD_REPEATS_REGION domain-containing protein.	0.981
B7P9S6_IXOSC	B7PE09_IXOSC	B7P9S6	B7PE09	Non-specific serine/threonine protein kinase.	RNA-binding protein musashi, putative.	0.974
B7P9S6_IXOSC	B7PF10_IXOSC	B7P9S6	B7PF10	Non-specific serine/threonine protein kinase.	RAS family protein, putative.	0.886
B7P9S6_IXOSC	B7PFU2_IXOSC	B7P9S6	B7PFU2	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.976
B7P9S6_IXOSC	B7PII7_IXOSC	B7P9S6	B7PII7	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.670
B7P9S6_IXOSC	B7PLB2_IXOSC	B7P9S6	B7PLB2	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.839
B7P9S6_IXOSC	B7PLB3_IXOSC	B7P9S6	B7PLB3	Non-specific serine/threonine protein kinase.	HEAT repeatcontaining protein.	0.989
B7P9S6_IXOSC	B7PLU8_IXOSC	B7P9S6	B7PLU8	Non-specific serine/threonine protein kinase.	40S ribosomal protein S6, putative (Fragment).	0.992
B7P9S6_IXOSC	B7PTK2_IXOSC	B7P9S6	B7PTK2	Non-specific serine/threonine protein kinase.	Eukaryotic translation initiation factor 4E binding protein, putative.	0.693
B7P9S6_IXOSC	B7Q018_IXOSC	B7P9S6	B7Q018	Non-specific serine/threonine protein kinase.	Peptidylprolyl isomerase.	0.831
B7P9S6_IXOSC	B7Q5U4_IXOSC	B7P9S6	B7Q5U4	Non-specific serine/threonine protein kinase.	MP1 adaptor interacting protein P14, putative.	0.612
B7P9S6_IXOSC	B7Q6G8_IXOSC	B7P9S6	B7Q6G8	Non-specific serine/threonine protein kinase.	GTP-binding protein, putative.	0.840
B7P9S6_IXOSC	B7Q942_IXOSC	B7P9S6	B7Q942	Non-specific serine/threonine protein kinase.	Translation initiation factor 4F, cap-binding subunit, putative; Belongs to the eukaryotic initiation factor 4E family.	0.583
B7P9S6_IXOSC	B7Q9E7_IXOSC	B7P9S6	B7Q9E7	Non-specific serine/threonine protein kinase.	Eukaryotic elongation factor 2 kinase.	0.743
B7P9S6_IXOSC	B7QCU2_IXOSC	B7P9S6	B7QCU2	Non-specific serine/threonine protein kinase.	Small GTPase involved in nuclear protein import, putative.	0.821
B7P9S6_IXOSC	B7QGH3_IXOSC	B7P9S6	B7QGH3	Non-specific serine/threonine protein kinase.	Amino acid transporter, putative.	0.437
B7P9S6_IXOSC	B7QGQ3_IXOSC	B7P9S6	B7QGQ3	Non-specific serine/threonine protein kinase.	143-3 isoform A isoform 2 family protein; Belongs to the 14-3-3 family.	0.464
B7P9S6_IXOSC	B7QH63_IXOSC	B7P9S6	B7QH63	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.409
B7PB41_IXOSC	B7P9S6_IXOSC	B7PB41	B7P9S6	WD_REPEATS_REGION domain-containing protein.	Non-specific serine/threonine protein kinase.	0.981
B7PB41_IXOSC	B7PF10_IXOSC	B7PB41	B7PF10	WD_REPEATS_REGION domain-containing protein.	RAS family protein, putative.	0.991