(90 nodes) RAB GEFs exchange GTP for GDP on RABs network (Ixodes scapularis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

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protein homology

Your Input:
	B7PKD1_IXOSC	Mbp-1 interacting protein-2A, putative. (140 aa)
	B7P199_IXOSC	Acid methyltransferase, putative. (281 aa)
	B7P1R1_IXOSC	Rab3 GTPaseactivating protein, non-catalytic subunit family protein. (971 aa)
	B7P283_IXOSC	Zinc finger protein, putative. (199 aa)
	B7P2U2_IXOSC	Foie-gras_1 domain-containing protein. (1184 aa)
	B7P2U6_IXOSC	Acid methyltransferase, putative. (179 aa)
	B7P3L4_IXOSC	Acid methyltransferase, putative. (291 aa)
	B7P3L6_IXOSC	Acid methyltransferase, putative. (295 aa)
	B7P4F9_IXOSC	RIC1 domain-containing protein. (328 aa)
	B7P4G0_IXOSC	RIC1 domain-containing protein. (878 aa)
	B7P4V7_IXOSC	GTP-binding protein RAB-32, putative. (228 aa)
	B7P5V5_IXOSC	RAC serine/threonine kinase, putative; Belongs to the protein kinase superfamily. (345 aa)
	B7P6C7_IXOSC	RAB-18, putative. (201 aa)
	B7P802_IXOSC	Map-kinase activating death domain protein, putative. (1523 aa)
	B7P991_IXOSC	Acid methyltransferase, putative. (288 aa)
	B7PAE0_IXOSC	RAS-related protein, putative. (215 aa)
	B7PB34_IXOSC	Acid methyltransferase, putative. (288 aa)
	B7PBJ4_IXOSC	Uncharacterized protein. (446 aa)
	B7PC20_IXOSC	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (218 aa)
	B7PEJ6_IXOSC	Synaptic vesicle-associated GTP-binding protein, putative. (219 aa)
	B7PFS7_IXOSC	Uncharacterized protein. (2064 aa)
	B7PG37_IXOSC	Acid methyltransferase, putative. (294 aa)
	B7PGW4_IXOSC	Vacuolar sorting protein 9 (vps9) domaincontaining protein. (263 aa)
	B7PH08_IXOSC	UDENN domain-containing protein. (596 aa)
	B7PHG1_IXOSC	cAMP-dependent protein kinase catalytic subunit, putative; Belongs to the protein kinase superfamily. (371 aa)
	B7PIH2_IXOSC	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (104 aa)
	B7PIZ1_IXOSC	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (446 aa)
	B7PJ89_IXOSC	Uncharacterized protein. (342 aa)
	B7PJ91_IXOSC	Junctophilin-2, putative. (527 aa)
	B7PKP3_IXOSC	Acid methyltransferase, putative. (300 aa)
	B7PLL2_IXOSC	Acid methyltransferase, putative. (295 aa)
	B7PM72_IXOSC	Acid methyltransferase, putative. (299 aa)
	B7PMP0_IXOSC	Acid methyltransferase, putative. (334 aa)
	B7PN94_IXOSC	Acid methyltransferase, putative. (265 aa)
	B7PQB1_IXOSC	Acid methyltransferase, putative. (285 aa)
	B7PQZ7_IXOSC	Acid methyltransferase, putative. (244 aa)
	B7PQZ8_IXOSC	Acid methyltransferase, putative. (227 aa)
	B7PR58_IXOSC	GTP binding protein Rab-1A. (82 aa)
	B7PR67_IXOSC	Acid methyltransferase, putative. (280 aa)
	B7PRY1_IXOSC	Uncharacterized protein. (949 aa)
	B7PSH4_IXOSC	Trafficking protein particle complex subunit 6B, putative. (162 aa)
	B7PSV6_IXOSC	Acid methyltransferase, putative. (178 aa)
	B7PSV7_IXOSC	Acid methyltransferase, putative. (159 aa)
	B7PT87_IXOSC	Translational initiation factor IF2, putative. (99 aa)
	B7PU12_IXOSC	Methyltransf_25 domain-containing protein. (194 aa)
	B7PU44_IXOSC	RabX4 family protein. (59 aa)
	B7PUN5_IXOSC	Acid methyltransferase, putative. (297 aa)
	B7PVS9_IXOSC	Acid methyltransferase, putative. (226 aa)
	B7PW52_IXOSC	NIK- and IKBKB-binding protein, putative. (1195 aa)
	B7PZ29_IXOSC	Denn domain-containing protein, putative. (370 aa)
	B7PZ70_IXOSC	RAS-related protein, putative. (126 aa)
	B7Q0A3_IXOSC	BTB domain-containing protein. (859 aa)
	B7Q0H8_IXOSC	WD-repeat protein, putative. (320 aa)
	B7Q0S6_IXOSC	RING-type domain-containing protein. (645 aa)
	B7Q159_IXOSC	RAB-3GAP1 protein, putative (Fragment). (258 aa)
	B7Q163_IXOSC	RAB-3 GTPase-activating protein catalytic subunit, putative. (475 aa)
	B7Q2C6_IXOSC	RAS-related protein, putative. (204 aa)
	B7Q3R1_IXOSC	Acid methyltransferase, putative. (296 aa)
	B7Q4D2_IXOSC	RAS-related protein, putative (Fragment). (149 aa)
	B7Q4D3_IXOSC	Rab39 family protein. (78 aa)
	B7Q5I4_IXOSC	Multifunctional chaperone, putative; Belongs to the 14-3-3 family. (258 aa)
	B7Q699_IXOSC	GTP-binding protein RAB-32, putative (Fragment). (178 aa)
	B7Q775_IXOSC	Acid methyltransferase, putative. (180 aa)
	B7Q7Q5_IXOSC	Uncharacterized protein. (139 aa)
	B7Q7R1_IXOSC	RAS-related protein, putative. (208 aa)
	B7Q821_IXOSC	Acid methyltransferase, putative. (226 aa)
	B7Q8G5_IXOSC	Uncharacterized protein. (381 aa)
	B7Q958_IXOSC	Acid methyltransferase, putative. (244 aa)
	B7QAP0_IXOSC	D-alanyl-D-alanine carboxypeptidase, putative. (476 aa)
	B7QAP1_IXOSC	TPR_REGION domain-containing protein. (82 aa)
	B7QCD0_IXOSC	Uncharacterized protein. (417 aa)
	B7QDB4_IXOSC	RAS-related protein, putative. (150 aa)
	B7QFX7_IXOSC	RAB-9 and, putative. (204 aa)
	B7QG33_IXOSC	Acid methyltransferase, putative. (220 aa)
	B7QGA1_IXOSC	Acid methyltransferase, putative. (215 aa)
	B7QGK2_IXOSC	Acid methyltransferase, putative. (241 aa)
	B7QH45_IXOSC	Trafficking protein particle complex subunit; May play a role in vesicular transport from endoplasmic reticulum to Golgi. (179 aa)
	B7QHS7_IXOSC	RAS-related protein, putative (Fragment). (218 aa)
	B7QHT0_IXOSC	Bhlh transcription factor, putative (Fragment). (125 aa)
	B7QI18_IXOSC	RAB GDP/GTP exchange factor, putative. (989 aa)
	B7QIZ6_IXOSC	Rab proteins geranylgeranyltransferase component A, putative. (722 aa)
	B7QJM3_IXOSC	GAPVD1 protein, putative (Fragment). (271 aa)
	B7QJM4_IXOSC	Uncharacterized protein. (301 aa)
	B7QJT7_IXOSC	Acid methyltransferase, putative. (152 aa)
	B7QK75_IXOSC	Uncharacterized protein. (148 aa)
	B7QK76_IXOSC	Rabin, putative. (403 aa)
	B7QLV2_IXOSC	Vacuolar fusion protein mon1 a family protein. (91 aa)
	B7QMC0_IXOSC	Acid methyltransferase, putative. (172 aa)
	B7QMK8_IXOSC	Acid methyltransferase, putative. (297 aa)
	B7QNB9_IXOSC	Acid methyltransferase, putative. (182 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P1R1_IXOSC	B7P6C7_IXOSC	B7P1R1	B7P6C7	Rab3 GTPaseactivating protein, non-catalytic subunit family protein.	RAB-18, putative.	0.850
B7P1R1_IXOSC	B7P802_IXOSC	B7P1R1	B7P802	Rab3 GTPaseactivating protein, non-catalytic subunit family protein.	Map-kinase activating death domain protein, putative.	0.604
B7P1R1_IXOSC	B7PIZ1_IXOSC	B7P1R1	B7PIZ1	Rab3 GTPaseactivating protein, non-catalytic subunit family protein.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.781
B7P1R1_IXOSC	B7Q159_IXOSC	B7P1R1	B7Q159	Rab3 GTPaseactivating protein, non-catalytic subunit family protein.	RAB-3GAP1 protein, putative (Fragment).	0.977
B7P1R1_IXOSC	B7Q163_IXOSC	B7P1R1	B7Q163	Rab3 GTPaseactivating protein, non-catalytic subunit family protein.	RAB-3 GTPase-activating protein catalytic subunit, putative.	0.977
B7P1R1_IXOSC	B7Q7R1_IXOSC	B7P1R1	B7Q7R1	Rab3 GTPaseactivating protein, non-catalytic subunit family protein.	RAS-related protein, putative.	0.663
B7P1R1_IXOSC	B7QIZ6_IXOSC	B7P1R1	B7QIZ6	Rab3 GTPaseactivating protein, non-catalytic subunit family protein.	Rab proteins geranylgeranyltransferase component A, putative.	0.697
B7P283_IXOSC	B7P802_IXOSC	B7P283	B7P802	Zinc finger protein, putative.	Map-kinase activating death domain protein, putative.	0.631
B7P283_IXOSC	B7PAE0_IXOSC	B7P283	B7PAE0	Zinc finger protein, putative.	RAS-related protein, putative.	0.416
B7P283_IXOSC	B7PIZ1_IXOSC	B7P283	B7PIZ1	Zinc finger protein, putative.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.825
B7P283_IXOSC	B7PZ29_IXOSC	B7P283	B7PZ29	Zinc finger protein, putative.	Denn domain-containing protein, putative.	0.975
B7P283_IXOSC	B7QHS7_IXOSC	B7P283	B7QHS7	Zinc finger protein, putative.	RAS-related protein, putative (Fragment).	0.430
B7P283_IXOSC	B7QIZ6_IXOSC	B7P283	B7QIZ6	Zinc finger protein, putative.	Rab proteins geranylgeranyltransferase component A, putative.	0.701
B7P2U2_IXOSC	B7PC20_IXOSC	B7P2U2	B7PC20	Foie-gras_1 domain-containing protein.	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	0.979
B7P2U2_IXOSC	B7PIH2_IXOSC	B7P2U2	B7PIH2	Foie-gras_1 domain-containing protein.	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	0.981
B7P2U2_IXOSC	B7PKD1_IXOSC	B7P2U2	B7PKD1	Foie-gras_1 domain-containing protein.	Mbp-1 interacting protein-2A, putative.	0.982
B7P2U2_IXOSC	B7PR58_IXOSC	B7P2U2	B7PR58	Foie-gras_1 domain-containing protein.	GTP binding protein Rab-1A.	0.430
B7P2U2_IXOSC	B7PRY1_IXOSC	B7P2U2	B7PRY1	Foie-gras_1 domain-containing protein.	Uncharacterized protein.	0.988
B7P2U2_IXOSC	B7PSH4_IXOSC	B7P2U2	B7PSH4	Foie-gras_1 domain-containing protein.	Trafficking protein particle complex subunit 6B, putative.	0.982
B7P2U2_IXOSC	B7PW52_IXOSC	B7P2U2	B7PW52	Foie-gras_1 domain-containing protein.	NIK- and IKBKB-binding protein, putative.	0.914