(17 nodes) Tyrosine kinase, catalytic domain network (Ixodes scapularis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B7QAX3_IXOSC	Tyrosine-protein kinase receptor. (711 aa)
	B7QBP3_IXOSC	Tyrosine-protein kinase. (626 aa)
	B7QM19_IXOSC	Tyrosine-protein kinase receptor. (1458 aa)
	B7QJ81_IXOSC	Eph receptor tyrosine kinase, putative. (902 aa)
	B7P4T8_IXOSC	Tyrosine protein kinase, putative. (1097 aa)
	B7P6H2_IXOSC	Tyrosine-protein kinase. (464 aa)
	B7P8S6_IXOSC	Protein kinase domaincontaining protein. (797 aa)
	B7P8W2_IXOSC	Nerve growth factor receptor TRKA, putative. (368 aa)
	B7PAB6_IXOSC	Nerve growth factor receptor TRKA, putative. (315 aa)
	B7PFB4_IXOSC	Nerve growth factor receptor TRKA, putative (Fragment). (246 aa)
	B7PFN0_IXOSC	Focal adhesion kinase, putative (Fragment). (975 aa)
	B7PIC9_IXOSC	Proto-oncogene receptor tyrosine protein kinase ret, putative; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1153 aa)
	B7PSP3_IXOSC	Non-specific protein-tyrosine kinase. (674 aa)
	B7PU79_IXOSC	Nerve growth factor receptor TRKA, putative. (259 aa)
	B7PZU9_IXOSC	Tyrosine kinase, putative. (486 aa)
	B7Q0S4_IXOSC	Tyrosine-protein kinase receptor. (829 aa)
	B7Q655_IXOSC	Receptor protein-tyrosine kinase. (982 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P4T8_IXOSC	B7P8S6_IXOSC	B7P4T8	B7P8S6	Tyrosine protein kinase, putative.	Protein kinase domaincontaining protein.	0.936
B7P4T8_IXOSC	B7PFN0_IXOSC	B7P4T8	B7PFN0	Tyrosine protein kinase, putative.	Focal adhesion kinase, putative (Fragment).	0.757
B7P4T8_IXOSC	B7PSP3_IXOSC	B7P4T8	B7PSP3	Tyrosine protein kinase, putative.	Non-specific protein-tyrosine kinase.	0.433
B7P4T8_IXOSC	B7Q655_IXOSC	B7P4T8	B7Q655	Tyrosine protein kinase, putative.	Receptor protein-tyrosine kinase.	0.608
B7P4T8_IXOSC	B7QBP3_IXOSC	B7P4T8	B7QBP3	Tyrosine protein kinase, putative.	Tyrosine-protein kinase.	0.525
B7P4T8_IXOSC	B7QJ81_IXOSC	B7P4T8	B7QJ81	Tyrosine protein kinase, putative.	Eph receptor tyrosine kinase, putative.	0.428
B7P6H2_IXOSC	B7Q655_IXOSC	B7P6H2	B7Q655	Tyrosine-protein kinase.	Receptor protein-tyrosine kinase.	0.482
B7P8S6_IXOSC	B7P4T8_IXOSC	B7P8S6	B7P4T8	Protein kinase domaincontaining protein.	Tyrosine protein kinase, putative.	0.936
B7P8S6_IXOSC	B7PFN0_IXOSC	B7P8S6	B7PFN0	Protein kinase domaincontaining protein.	Focal adhesion kinase, putative (Fragment).	0.684
B7P8S6_IXOSC	B7PSP3_IXOSC	B7P8S6	B7PSP3	Protein kinase domaincontaining protein.	Non-specific protein-tyrosine kinase.	0.413
B7P8S6_IXOSC	B7Q655_IXOSC	B7P8S6	B7Q655	Protein kinase domaincontaining protein.	Receptor protein-tyrosine kinase.	0.988
B7P8S6_IXOSC	B7QJ81_IXOSC	B7P8S6	B7QJ81	Protein kinase domaincontaining protein.	Eph receptor tyrosine kinase, putative.	0.407
B7P8W2_IXOSC	B7Q655_IXOSC	B7P8W2	B7Q655	Nerve growth factor receptor TRKA, putative.	Receptor protein-tyrosine kinase.	0.415
B7PFB4_IXOSC	B7Q655_IXOSC	B7PFB4	B7Q655	Nerve growth factor receptor TRKA, putative (Fragment).	Receptor protein-tyrosine kinase.	0.923
B7PFN0_IXOSC	B7P4T8_IXOSC	B7PFN0	B7P4T8	Focal adhesion kinase, putative (Fragment).	Tyrosine protein kinase, putative.	0.757
B7PFN0_IXOSC	B7P8S6_IXOSC	B7PFN0	B7P8S6	Focal adhesion kinase, putative (Fragment).	Protein kinase domaincontaining protein.	0.684
B7PFN0_IXOSC	B7Q655_IXOSC	B7PFN0	B7Q655	Focal adhesion kinase, putative (Fragment).	Receptor protein-tyrosine kinase.	0.820
B7PFN0_IXOSC	B7QJ81_IXOSC	B7PFN0	B7QJ81	Focal adhesion kinase, putative (Fragment).	Eph receptor tyrosine kinase, putative.	0.462
B7PSP3_IXOSC	B7P4T8_IXOSC	B7PSP3	B7P4T8	Non-specific protein-tyrosine kinase.	Tyrosine protein kinase, putative.	0.433
B7PSP3_IXOSC	B7P8S6_IXOSC	B7PSP3	B7P8S6	Non-specific protein-tyrosine kinase.	Protein kinase domaincontaining protein.	0.413