(51 nodes) Phosphatidylinositol signaling system network (Ixodes scapularis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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co-expression

protein homology

Your Input:
	B7P155_IXOSC	FYVE finger-containing phosphoinositide kinase, fyv1, putative. (2002 aa)
	B7P1V0_IXOSC	Type IV inositol 5-phosphatase, putative. (535 aa)
	B7P3Q2_IXOSC	Phosphatidylinositol 4-kinase type-II, putative (Fragment). (433 aa)
	B7P3X2_IXOSC	Calmodulin, putative; Belongs to the calmodulin family. (159 aa)
	B7P4X9_IXOSC	Phosphoinositide phospholipase C. (1201 aa)
	B7P5R7_IXOSC	Diacylglycerol kinase. (524 aa)
	B7P6C6_IXOSC	Inositol polyphosphate-1-phosphatase, putative. (394 aa)
	B7P6Q5_IXOSC	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1109 aa)
	B7P6Q6_IXOSC	Phosphoinositide phospholipase C. (754 aa)
	B7P880_IXOSC	Kinase; Belongs to the inositol phosphokinase (IPK) family. (278 aa)
	B7PBL0_IXOSC	Phosphatidylinositol-4-phosphate 5-kinase type I, putative (Fragment). (355 aa)
	B7PG26_IXOSC	Diacylglycerol kinase. (851 aa)
	B7PGU1_IXOSC	Myotubularin phosphatase domain-containing protein. (584 aa)
	B7PHD3_IXOSC	Calmodulin, putative; Belongs to the calmodulin family. (77 aa)
	B7PIF4_IXOSC	Phosphatidylinositol 3-kinase class, putative; Belongs to the PI3/PI4-kinase family. (1142 aa)
	B7PK64_IXOSC	Synaptojanin, putative. (921 aa)
	B7PLK9_IXOSC	Type I inositol-1,4,5-trisphosphate 5-phosphatase, putative (Fragment). (324 aa)
	B7PMG0_IXOSC	Suppressor of actin, putative. (528 aa)
	B7PN04_IXOSC	Uncharacterized protein. (689 aa)
	B7PTD3_IXOSC	Inositol monophosphatase, putative. (331 aa)
	B7PVF6_IXOSC	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (217 aa)
	B7PWS6_IXOSC	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
	B7PXE6_IXOSC	Phosphatidylinositol 4 kinase, putative (Fragment); Belongs to the PI3/PI4-kinase family. (2041 aa)
	B7PZD2_IXOSC	Phosphatidylinositol-4-phosphate 5-kinase type II, putative (Fragment). (365 aa)
	B7PZE1_IXOSC	Calmodulin, putative. (157 aa)
	B7Q0U6_IXOSC	Uncharacterized protein. (561 aa)
	B7Q1P7_IXOSC	Phosphatidylinositol 3-kinase class, putative (Fragment); Belongs to the PI3/PI4-kinase family. (864 aa)
	B7Q2N6_IXOSC	Phosphoinositide phospholipase C. (775 aa)
	B7Q370_IXOSC	Nonmuscle myosin essential light chain, putative; Belongs to the calmodulin family. (143 aa)
	B7Q3L3_IXOSC	Kinase; Belongs to the inositol phosphokinase (IPK) family. (445 aa)
	B7Q3R8_IXOSC	Calmodulin, putative. (180 aa)
	B7Q548_IXOSC	Phosphoinositide-3-kinase, regulatory subunit, putative. (427 aa)
	B7Q6K8_IXOSC	Phosphatidylinositol 3-kinase catalytic subunit, putative; Belongs to the PI3/PI4-kinase family. (491 aa)
	B7Q941_IXOSC	TPIP alpha lipid phosphatase, putative. (363 aa)
	B7QCF2_IXOSC	Calmodulin, putative; Belongs to the calmodulin family. (88 aa)
	B7QCY8_IXOSC	Phosphatidylinositol synthase, putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (190 aa)
	B7QDL1_IXOSC	Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (295 aa)
	B7QE75_IXOSC	Diacylglycerol kinase. (831 aa)
	B7QET6_IXOSC	Phosphatidylinositol 3-kinase class, putative; Belongs to the PI3/PI4-kinase family. (1638 aa)
	B7QF50_IXOSC	Phosphatidylinositol synthase, putative (Fragment); Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (220 aa)
	B7QFN8_IXOSC	Phosphatidate cytidylyltransferase; Belongs to the CDS family. (385 aa)
	B7QHI1_IXOSC	Myotubularin phosphatase domain-containing protein. (554 aa)
	B7QI04_IXOSC	Inositol-tetrakisphosphate 1-kinase, putative (Fragment). (297 aa)
	B7QJF5_IXOSC	Phosphatidylinositol 3-kinase catalytic subunit, putative (Fragment); Belongs to the PI3/PI4-kinase family. (617 aa)
	B7QJR4_IXOSC	Kinase; Belongs to the inositol phosphokinase (IPK) family. (240 aa)
	B7QK31_IXOSC	Centrin, putative (Fragment); Belongs to the calmodulin family. (151 aa)
	B7QKB8_IXOSC	Phosphatidylinositol 4 kinase, putative; Belongs to the PI3/PI4-kinase family. (2088 aa)
	B7QKP6_IXOSC	Type 3 inositol 1,4,5-trisphosphate receptor, putative. (2569 aa)
	B7QL46_IXOSC	Suppressor of actin, putative. (374 aa)
	B7QL47_IXOSC	Suppressor of actin, putative. (556 aa)
	B7QN19_IXOSC	Kinase; Belongs to the inositol phosphokinase (IPK) family. (259 aa)

Your Current Organism:

Ixodes scapularis

NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7P155_IXOSC	B7P3Q2_IXOSC	B7P155	B7P3Q2	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Phosphatidylinositol 4-kinase type-II, putative (Fragment).	0.946
B7P155_IXOSC	B7P4X9_IXOSC	B7P155	B7P4X9	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Phosphoinositide phospholipase C.	0.900
B7P155_IXOSC	B7P6Q5_IXOSC	B7P155	B7P6Q5	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.901
B7P155_IXOSC	B7P6Q6_IXOSC	B7P155	B7P6Q6	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Phosphoinositide phospholipase C.	0.900
B7P155_IXOSC	B7PGU1_IXOSC	B7P155	B7PGU1	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Myotubularin phosphatase domain-containing protein.	0.902
B7P155_IXOSC	B7PIF4_IXOSC	B7P155	B7PIF4	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Phosphatidylinositol 3-kinase class, putative; Belongs to the PI3/PI4-kinase family.	0.919
B7P155_IXOSC	B7PMG0_IXOSC	B7P155	B7PMG0	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Suppressor of actin, putative.	0.940
B7P155_IXOSC	B7PN04_IXOSC	B7P155	B7PN04	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Uncharacterized protein.	0.939
B7P155_IXOSC	B7PVF6_IXOSC	B7P155	B7PVF6	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).	0.902
B7P155_IXOSC	B7PXE6_IXOSC	B7P155	B7PXE6	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Phosphatidylinositol 4 kinase, putative (Fragment); Belongs to the PI3/PI4-kinase family.	0.936
B7P155_IXOSC	B7PZD2_IXOSC	B7P155	B7PZD2	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Phosphatidylinositol-4-phosphate 5-kinase type II, putative (Fragment).	0.926
B7P155_IXOSC	B7Q0U6_IXOSC	B7P155	B7Q0U6	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Uncharacterized protein.	0.923
B7P155_IXOSC	B7Q1P7_IXOSC	B7P155	B7Q1P7	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Phosphatidylinositol 3-kinase class, putative (Fragment); Belongs to the PI3/PI4-kinase family.	0.976
B7P155_IXOSC	B7Q2N6_IXOSC	B7P155	B7Q2N6	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Phosphoinositide phospholipase C.	0.901
B7P155_IXOSC	B7Q548_IXOSC	B7P155	B7Q548	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Phosphoinositide-3-kinase, regulatory subunit, putative.	0.901
B7P155_IXOSC	B7Q6K8_IXOSC	B7P155	B7Q6K8	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Phosphatidylinositol 3-kinase catalytic subunit, putative; Belongs to the PI3/PI4-kinase family.	0.904
B7P155_IXOSC	B7Q941_IXOSC	B7P155	B7Q941	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	TPIP alpha lipid phosphatase, putative.	0.925
B7P155_IXOSC	B7QCY8_IXOSC	B7P155	B7QCY8	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Phosphatidylinositol synthase, putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.910
B7P155_IXOSC	B7QET6_IXOSC	B7P155	B7QET6	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Phosphatidylinositol 3-kinase class, putative; Belongs to the PI3/PI4-kinase family.	0.924
B7P155_IXOSC	B7QF50_IXOSC	B7P155	B7QF50	FYVE finger-containing phosphoinositide kinase, fyv1, putative.	Phosphatidylinositol synthase, putative (Fragment); Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.915