(33 nodes) Small-subunit processome, and Regulation of transcription by RNA polymerase I network (Saprolegnia parasitica)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	SPRG_15430	WD_REPEATS_REGION domain-containing protein. (988 aa)
	SPRG_10951	18S rRNA biogenesis protein RCL1. (376 aa)
	SPRG_14146	RRP7 domain-containing protein. (245 aa)
	SPRG_13730	Brix domain-containing protein. (287 aa)
	SPRG_11352	WD_REPEATS_REGION domain-containing protein. (611 aa)
	SPRG_12284	Nop domain-containing protein. (483 aa)
	SPRG_09778	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (244 aa)
	SPRG_11447	WD_REPEATS_REGION domain-containing protein. (749 aa)
	SPRG_22333	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (615 aa)
	SPRG_10701	Uncharacterized protein. (420 aa)
	SPRG_08561	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1078 aa)
	SPRG_07725	Uncharacterized protein. (213 aa)
	SPRG_07088	CBF domain-containing protein. (581 aa)
	SPRG_10894	Nop domain-containing protein. (492 aa)
	SPRG_09636	Uncharacterized protein. (284 aa)
	SPRG_07434	Uncharacterized protein. (862 aa)
	SPRG_20018	Sas10 domain-containing protein. (506 aa)
	SPRG_06108	WD_REPEATS_REGION domain-containing protein. (906 aa)
	SPRG_07257	WD_REPEATS_REGION domain-containing protein. (508 aa)
	SPRG_03851	WD_REPEATS_REGION domain-containing protein. (333 aa)
	SPRG_04028	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
	SPRG_06286	Uncharacterized protein. (1836 aa)
	SPRG_03710	WD_REPEATS_REGION domain-containing protein. (678 aa)
	SPRG_19098	Uncharacterized protein. (622 aa)
	SPRG_02318	WD_REPEATS_REGION domain-containing protein. (810 aa)
	SPRG_00426	BP28CT domain-containing protein. (1955 aa)
	SPRG_03143	S4 RNA-binding domain-containing protein. (183 aa)
	SPRG_00553	Uncharacterized protein. (343 aa)
	SPRG_18842	WD_REPEATS_REGION domain-containing protein. (446 aa)
	SPRG_18957	WD_REPEATS_REGION domain-containing protein. (527 aa)
	SPRG_01078	Uncharacterized protein. (454 aa)
	SPRG_00194	WD_REPEATS_REGION domain-containing protein. (704 aa)
	SPRG_01346	rRNA-processing protein FCF1. (197 aa)

Your Current Organism:

Saprolegnia parasitica

NCBI taxonomy Id: 695850
Other names: S. parasitica CBS 223.65, Saprolegnia parasitica CBS 223.65

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPRG_00194	SPRG_00426	A0A067D1H3	A0A067CY02	WD_REPEATS_REGION domain-containing protein.	BP28CT domain-containing protein.	0.999
SPRG_00194	SPRG_00553	A0A067D1H3	A0A067CYY5	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.996
SPRG_00194	SPRG_01078	A0A067D1H3	A0A067D0H6	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.995
SPRG_00194	SPRG_01346	A0A067D1H3	A0A067D4Y6	WD_REPEATS_REGION domain-containing protein.	rRNA-processing protein FCF1.	0.989
SPRG_00194	SPRG_02318	A0A067D1H3	A0A067CW69	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.999
SPRG_00194	SPRG_03143	A0A067D1H3	A0A067CYP3	WD_REPEATS_REGION domain-containing protein.	S4 RNA-binding domain-containing protein.	0.989
SPRG_00194	SPRG_03710	A0A067D1H3	A0A067CRC6	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.997
SPRG_00194	SPRG_03851	A0A067D1H3	A0A067CL64	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.999
SPRG_00194	SPRG_04028	A0A067D1H3	A0A067CLL4	WD_REPEATS_REGION domain-containing protein.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.997
SPRG_00194	SPRG_06108	A0A067D1H3	A0A067CEW8	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.999
SPRG_00194	SPRG_06286	A0A067D1H3	A0A067CN71	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.999
SPRG_00194	SPRG_07088	A0A067D1H3	A0A067C9P5	WD_REPEATS_REGION domain-containing protein.	CBF domain-containing protein.	0.999
SPRG_00194	SPRG_07257	A0A067D1H3	A0A067CFM1	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.999
SPRG_00194	SPRG_07434	A0A067D1H3	A0A067CDH2	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.997
SPRG_00194	SPRG_07725	A0A067D1H3	A0A067C920	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.997
SPRG_00194	SPRG_08561	A0A067D1H3	A0A067C634	WD_REPEATS_REGION domain-containing protein.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.997
SPRG_00194	SPRG_09636	A0A067D1H3	A0A067CDA7	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.999
SPRG_00194	SPRG_09778	A0A067D1H3	A0A067C2P3	WD_REPEATS_REGION domain-containing protein.	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	0.997
SPRG_00194	SPRG_10701	A0A067D1H3	A0A067C4D5	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.996
SPRG_00194	SPRG_10894	A0A067D1H3	A0A067CC41	WD_REPEATS_REGION domain-containing protein.	Nop domain-containing protein.	0.999