(42 nodes) Mixed, incl. Cullin family protein binding, and Ubiquitin protein ligase binding network (Saprolegnia parasitica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPRG_18016	Uncharacterized protein. (756 aa)
	SPRG_17573	Uncharacterized protein; Belongs to the SKP1 family. (156 aa)
	SPRG_16674	Uncharacterized protein. (251 aa)
	SPRG_15804	WD_REPEATS_REGION domain-containing protein. (132 aa)
	SPRG_14074	B30.2/SPRY domain-containing protein. (312 aa)
	SPRG_16998	Uncharacterized protein. (321 aa)
	SPRG_16675	Uncharacterized protein. (251 aa)
	SPRG_16596	F-box domain-containing protein. (317 aa)
	SPRG_10002	CULLIN_2 domain-containing protein; Belongs to the cullin family. (754 aa)
	SPRG_09875	Uncharacterized protein. (251 aa)
	SPRG_10403	Uncharacterized protein. (193 aa)
	SPRG_11654	RING-type domain-containing protein. (102 aa)
	SPRG_12515	Uncharacterized protein. (202 aa)
	SPRG_11296	E2_bind domain-containing protein. (458 aa)
	SPRG_20791	Uncharacterized protein. (636 aa)
	SPRG_09876	Uncharacterized protein. (251 aa)
	SPRG_21242	NEDD8-activating enzyme E1 regulatory subunit. (508 aa)
	SPRG_09954	Uncharacterized protein. (546 aa)
	SPRG_10734	Uncharacterized protein. (570 aa)
	SPRG_11463	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (103 aa)
	SPRG_07658	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (216 aa)
	SPRG_06023	Uncharacterized protein. (438 aa)
	SPRG_09378	Uncharacterized protein. (416 aa)
	SPRG_05966	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (283 aa)
	SPRG_06300	Uncharacterized protein. (1372 aa)
	SPRG_08828	CULLIN_2 domain-containing protein; Belongs to the cullin family. (755 aa)
	SPRG_20603	Uncharacterized protein. (103 aa)
	SPRG_05099	Uncharacterized protein; Belongs to the SKP1 family. (161 aa)
	SPRG_03925	Lipase_3 domain-containing protein. (848 aa)
	SPRG_06993	Uncharacterized protein. (938 aa)
	SPRG_06783	Uncharacterized protein. (632 aa)
	SPRG_04726	Uncharacterized protein. (1709 aa)
	SPRG_06670	UBIQUITIN_CONJUGAT_2 domain-containing protein. (230 aa)
	SPRG_05824	Uncharacterized protein; Belongs to the SKP1 family. (156 aa)
	SPRG_01673	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (267 aa)
	SPRG_05334	Uncharacterized protein; Belongs to the SKP1 family. (168 aa)
	SPRG_04452	Uncharacterized protein. (322 aa)
	SPRG_01077	CULLIN_2 domain-containing protein; Belongs to the cullin family. (744 aa)
	SPRG_00693	Uncharacterized protein. (303 aa)
	SPRG_01567	Uncharacterized protein. (147 aa)
	SPRG_00076	Uncharacterized protein. (955 aa)
	SPRG_00155	BTB domain-containing protein. (317 aa)

Your Current Organism:

Saprolegnia parasitica

NCBI taxonomy Id: 695850
Other names: S. parasitica CBS 223.65, Saprolegnia parasitica CBS 223.65

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPRG_00076	SPRG_01077	A0A067D9D4	A0A067CWD0	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.448
SPRG_00076	SPRG_03925	A0A067D9D4	A0A067CKS2	Uncharacterized protein.	Lipase_3 domain-containing protein.	0.448
SPRG_00076	SPRG_04452	A0A067D9D4	A0A067CVJ5	Uncharacterized protein.	Uncharacterized protein.	0.428
SPRG_00076	SPRG_05099	A0A067D9D4	A0A067CIP5	Uncharacterized protein.	Uncharacterized protein; Belongs to the SKP1 family.	0.623
SPRG_00076	SPRG_05334	A0A067D9D4	A0A067CTN9	Uncharacterized protein.	Uncharacterized protein; Belongs to the SKP1 family.	0.623
SPRG_00076	SPRG_05824	A0A067D9D4	A0A067CR59	Uncharacterized protein.	Uncharacterized protein; Belongs to the SKP1 family.	0.623
SPRG_00076	SPRG_08828	A0A067D9D4	A0A067CH64	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.448
SPRG_00076	SPRG_09875	A0A067D9D4	A0A067C0G0	Uncharacterized protein.	Uncharacterized protein.	0.623
SPRG_00076	SPRG_09876	A0A067D9D4	A0A067C547	Uncharacterized protein.	Uncharacterized protein.	0.623
SPRG_00076	SPRG_10002	A0A067D9D4	A0A067BXH4	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.448
SPRG_00076	SPRG_16674	A0A067D9D4	A0A067BMC5	Uncharacterized protein.	Uncharacterized protein.	0.623
SPRG_00076	SPRG_16675	A0A067D9D4	A0A067BUC2	Uncharacterized protein.	Uncharacterized protein.	0.623
SPRG_00076	SPRG_16998	A0A067D9D4	A0A067BTJ1	Uncharacterized protein.	Uncharacterized protein.	0.428
SPRG_00076	SPRG_17573	A0A067D9D4	A0A067BFQ6	Uncharacterized protein.	Uncharacterized protein; Belongs to the SKP1 family.	0.623
SPRG_00155	SPRG_01077	A0A067D9I3	A0A067CWD0	BTB domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.849
SPRG_00155	SPRG_03925	A0A067D9I3	A0A067CKS2	BTB domain-containing protein.	Lipase_3 domain-containing protein.	0.816
SPRG_00155	SPRG_08828	A0A067D9I3	A0A067CH64	BTB domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.816
SPRG_00155	SPRG_10002	A0A067D9I3	A0A067BXH4	BTB domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.816
SPRG_00155	SPRG_11654	A0A067D9I3	A0A067C2H1	BTB domain-containing protein.	RING-type domain-containing protein.	0.744
SPRG_00693	SPRG_01077	A0A067CZE9	A0A067CWD0	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.620