(11 nodes) Mixed, incl. Actin capping, and Dynactin complex network (Saprolegnia parasitica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPRG_15353	Uncharacterized protein. (435 aa)
	SPRG_10768	Uncharacterized protein. (179 aa)
	SPRG_13909	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (273 aa)
	SPRG_08855	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (287 aa)
	SPRG_20087	Pept_C1 domain-containing protein; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments; Belongs to the peptidase C1 family. (484 aa)
	SPRG_20565	CAP-Gly domain-containing protein. (1189 aa)
	SPRG_05848	CAP-Gly domain-containing protein. (465 aa)
	SPRG_05132	Uncharacterized protein. (373 aa)
	SPRG_02811	Uncharacterized protein; Belongs to the actin family. (332 aa)
	SPRG_00381	Uncharacterized protein. (724 aa)
	SPRG_02280	Uncharacterized protein; Belongs to the actin family. (510 aa)

Your Current Organism:

Saprolegnia parasitica

NCBI taxonomy Id: 695850
Other names: S. parasitica CBS 223.65, Saprolegnia parasitica CBS 223.65

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPRG_00381	SPRG_02280	A0A067D207	A0A067D359	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.777
SPRG_00381	SPRG_02811	A0A067D207	A0A067CZV6	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.777
SPRG_00381	SPRG_05132	A0A067D207	A0A067CT18	Uncharacterized protein.	Uncharacterized protein.	0.994
SPRG_00381	SPRG_05848	A0A067D207	A0A067CS16	Uncharacterized protein.	CAP-Gly domain-containing protein.	0.908
SPRG_00381	SPRG_08855	A0A067D207	A0A067C555	Uncharacterized protein.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.956
SPRG_00381	SPRG_10768	A0A067D207	A0A067BZ65	Uncharacterized protein.	Uncharacterized protein.	0.999
SPRG_00381	SPRG_13909	A0A067D207	A0A067C1Q0	Uncharacterized protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.939
SPRG_00381	SPRG_15353	A0A067D207	A0A067BMK0	Uncharacterized protein.	Uncharacterized protein.	0.999
SPRG_00381	SPRG_20087	A0A067D207	A0A067CEP4	Uncharacterized protein.	Pept_C1 domain-containing protein; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments; Belongs to the peptidase C1 family.	0.939
SPRG_00381	SPRG_20565	A0A067D207	A0A067CIY9	Uncharacterized protein.	CAP-Gly domain-containing protein.	0.908
SPRG_02280	SPRG_00381	A0A067D359	A0A067D207	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.777
SPRG_02280	SPRG_05132	A0A067D359	A0A067CT18	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.786
SPRG_02280	SPRG_05848	A0A067D359	A0A067CS16	Uncharacterized protein; Belongs to the actin family.	CAP-Gly domain-containing protein.	0.599
SPRG_02280	SPRG_08855	A0A067D359	A0A067C555	Uncharacterized protein; Belongs to the actin family.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.767
SPRG_02280	SPRG_10768	A0A067D359	A0A067BZ65	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.779
SPRG_02280	SPRG_13909	A0A067D359	A0A067C1Q0	Uncharacterized protein; Belongs to the actin family.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.696
SPRG_02280	SPRG_15353	A0A067D359	A0A067BMK0	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.776
SPRG_02280	SPRG_20087	A0A067D359	A0A067CEP4	Uncharacterized protein; Belongs to the actin family.	Pept_C1 domain-containing protein; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments; Belongs to the peptidase C1 family.	0.696
SPRG_02280	SPRG_20565	A0A067D359	A0A067CIY9	Uncharacterized protein; Belongs to the actin family.	CAP-Gly domain-containing protein.	0.599
SPRG_02811	SPRG_00381	A0A067CZV6	A0A067D207	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.777