(5 nodes) Spindle checkpoint signaling network (Saprolegnia parasitica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPRG_10516	TTK protein kinase. (851 aa)
	SPRG_06144	Uncharacterized protein. (718 aa)
	SPRG_09746	BUB1 N-terminal domain-containing protein. (634 aa)
	SPRG_06295	Mitotic spindle assembly checkpoint protein MAD2A. (208 aa)
	SPRG_18827	DEP domain-containing protein. (279 aa)

Your Current Organism:

Saprolegnia parasitica

NCBI taxonomy Id: 695850
Other names: S. parasitica CBS 223.65, Saprolegnia parasitica CBS 223.65

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPRG_06144	SPRG_06295	A0A067CEB1	A0A067CGG7	Uncharacterized protein.	Mitotic spindle assembly checkpoint protein MAD2A.	0.998
SPRG_06144	SPRG_09746	A0A067CEB1	A0A067CEM9	Uncharacterized protein.	BUB1 N-terminal domain-containing protein.	0.966
SPRG_06144	SPRG_10516	A0A067CEB1	A0A067BZQ7	Uncharacterized protein.	TTK protein kinase.	0.905
SPRG_06144	SPRG_18827	A0A067CEB1	A0A067D2H0	Uncharacterized protein.	DEP domain-containing protein.	0.847
SPRG_06295	SPRG_06144	A0A067CGG7	A0A067CEB1	Mitotic spindle assembly checkpoint protein MAD2A.	Uncharacterized protein.	0.998
SPRG_06295	SPRG_09746	A0A067CGG7	A0A067CEM9	Mitotic spindle assembly checkpoint protein MAD2A.	BUB1 N-terminal domain-containing protein.	0.993
SPRG_06295	SPRG_10516	A0A067CGG7	A0A067BZQ7	Mitotic spindle assembly checkpoint protein MAD2A.	TTK protein kinase.	0.989
SPRG_06295	SPRG_18827	A0A067CGG7	A0A067D2H0	Mitotic spindle assembly checkpoint protein MAD2A.	DEP domain-containing protein.	0.910
SPRG_09746	SPRG_06144	A0A067CEM9	A0A067CEB1	BUB1 N-terminal domain-containing protein.	Uncharacterized protein.	0.966
SPRG_09746	SPRG_06295	A0A067CEM9	A0A067CGG7	BUB1 N-terminal domain-containing protein.	Mitotic spindle assembly checkpoint protein MAD2A.	0.993
SPRG_09746	SPRG_10516	A0A067CEM9	A0A067BZQ7	BUB1 N-terminal domain-containing protein.	TTK protein kinase.	0.906
SPRG_09746	SPRG_18827	A0A067CEM9	A0A067D2H0	BUB1 N-terminal domain-containing protein.	DEP domain-containing protein.	0.843
SPRG_10516	SPRG_06144	A0A067BZQ7	A0A067CEB1	TTK protein kinase.	Uncharacterized protein.	0.905
SPRG_10516	SPRG_06295	A0A067BZQ7	A0A067CGG7	TTK protein kinase.	Mitotic spindle assembly checkpoint protein MAD2A.	0.989
SPRG_10516	SPRG_09746	A0A067BZQ7	A0A067CEM9	TTK protein kinase.	BUB1 N-terminal domain-containing protein.	0.906
SPRG_10516	SPRG_18827	A0A067BZQ7	A0A067D2H0	TTK protein kinase.	DEP domain-containing protein.	0.555
SPRG_18827	SPRG_06144	A0A067D2H0	A0A067CEB1	DEP domain-containing protein.	Uncharacterized protein.	0.847
SPRG_18827	SPRG_06295	A0A067D2H0	A0A067CGG7	DEP domain-containing protein.	Mitotic spindle assembly checkpoint protein MAD2A.	0.910
SPRG_18827	SPRG_09746	A0A067D2H0	A0A067CEM9	DEP domain-containing protein.	BUB1 N-terminal domain-containing protein.	0.843
SPRG_18827	SPRG_10516	A0A067D2H0	A0A067BZQ7	DEP domain-containing protein.	TTK protein kinase.	0.555