(40 nodes) Negative regulation of cell cycle process network (Saprolegnia parasitica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPRG_22067	Uncharacterized protein. (844 aa)
	SPRG_18972	Rod_C domain-containing protein. (830 aa)
	SPRG_19231	Uncharacterized protein. (501 aa)
	SPRG_02075	Uncharacterized protein. (313 aa)
	SPRG_01251	Uncharacterized protein. (1214 aa)
	SPRG_19230	Uncharacterized protein. (238 aa)
	SPRG_05293	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2657 aa)
	SPRG_02867	Checkpoint protein; Belongs to the HUS1 family. (281 aa)
	SPRG_19229	Uncharacterized protein. (240 aa)
	SPRG_19172	Swi3 domain-containing protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (428 aa)
	SPRG_05888	AAA domain-containing protein. (1443 aa)
	SPRG_05390	E2F_TDP domain-containing protein. (345 aa)
	SPRG_06984	WAPL domain-containing protein. (587 aa)
	SPRG_07650	DOT1 domain-containing protein. (347 aa)
	SPRG_08175	ERCC4 domain-containing protein. (553 aa)
	SPRG_08426	Uncharacterized protein. (906 aa)
	SPRG_19738	WD_REPEATS_REGION domain-containing protein. (460 aa)
	SPRG_06295	Mitotic spindle assembly checkpoint protein MAD2A. (208 aa)
	SPRG_09746	BUB1 N-terminal domain-containing protein. (634 aa)
	SPRG_06144	Uncharacterized protein. (718 aa)
	SPRG_09747	BUB protein kinase. (360 aa)
	SPRG_10631	FHA domain-containing protein. (593 aa)
	SPRG_07979	Uncharacterized protein. (990 aa)
	SPRG_07532	Uncharacterized protein. (989 aa)
	SPRG_09881	Uncharacterized protein. (798 aa)
	SPRG_10513	Uncharacterized protein. (394 aa)
	SPRG_11639	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (359 aa)
	SPRG_10364	DOT1 domain-containing protein. (566 aa)
	SPRG_10516	TTK protein kinase. (851 aa)
	SPRG_18588	ERCC4 domain-containing protein. (362 aa)
	SPRG_14470	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (962 aa)
	SPRG_13406	WD_REPEATS_REGION domain-containing protein. (330 aa)
	SPRG_12244	DOT1 domain-containing protein. (262 aa)
	SPRG_15598	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (525 aa)
	SPRG_22315	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2701 aa)
	SPRG_13408	Uncharacterized protein. (147 aa)
	SPRG_16457	Uncharacterized protein. (303 aa)
	SPRG_18488	WD_REPEATS_REGION domain-containing protein. (139 aa)
	SPRG_18199	DOT1 domain-containing protein. (255 aa)
	SPRG_15159	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (296 aa)

Your Current Organism:

Saprolegnia parasitica

NCBI taxonomy Id: 695850
Other names: S. parasitica CBS 223.65, Saprolegnia parasitica CBS 223.65

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPRG_01251	SPRG_05888	A0A067CXH4	A0A067CRB4	Uncharacterized protein.	AAA domain-containing protein.	0.562
SPRG_01251	SPRG_06295	A0A067CXH4	A0A067CGG7	Uncharacterized protein.	Mitotic spindle assembly checkpoint protein MAD2A.	0.790
SPRG_01251	SPRG_09746	A0A067CXH4	A0A067CEM9	Uncharacterized protein.	BUB1 N-terminal domain-containing protein.	0.660
SPRG_01251	SPRG_09747	A0A067CXH4	A0A067CDW5	Uncharacterized protein.	BUB protein kinase.	0.660
SPRG_01251	SPRG_10516	A0A067CXH4	A0A067BZQ7	Uncharacterized protein.	TTK protein kinase.	0.742
SPRG_01251	SPRG_13406	A0A067CXH4	A0A067BQW9	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.473
SPRG_01251	SPRG_18488	A0A067CXH4	A0A067BCX5	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.473
SPRG_01251	SPRG_22067	A0A067CXH4	A0A067D5X3	Uncharacterized protein.	Uncharacterized protein.	0.980
SPRG_02075	SPRG_02867	A0A067D3H2	A0A067CT11	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.999
SPRG_02075	SPRG_05293	A0A067D3H2	A0A067CTJ4	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.893
SPRG_02075	SPRG_05888	A0A067D3H2	A0A067CRB4	Uncharacterized protein.	AAA domain-containing protein.	0.473
SPRG_02075	SPRG_08175	A0A067D3H2	A0A067CHT1	Uncharacterized protein.	ERCC4 domain-containing protein.	0.484
SPRG_02075	SPRG_09881	A0A067D3H2	A0A067C551	Uncharacterized protein.	Uncharacterized protein.	0.807
SPRG_02075	SPRG_10631	A0A067D3H2	A0A067CBP6	Uncharacterized protein.	FHA domain-containing protein.	0.823
SPRG_02075	SPRG_14470	A0A067D3H2	A0A067BP38	Uncharacterized protein.	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	0.843
SPRG_02075	SPRG_15598	A0A067D3H2	A0A067BSV5	Uncharacterized protein.	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	0.843
SPRG_02075	SPRG_16457	A0A067D3H2	A0A067BV15	Uncharacterized protein.	Uncharacterized protein.	0.999
SPRG_02075	SPRG_18588	A0A067D3H2	A0A067BND5	Uncharacterized protein.	ERCC4 domain-containing protein.	0.484
SPRG_02075	SPRG_19172	A0A067D3H2	A0A067CS53	Uncharacterized protein.	Swi3 domain-containing protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.771
SPRG_02075	SPRG_19229	A0A067D3H2	A0A067CSB7	Uncharacterized protein.	Uncharacterized protein.	0.979