(160 nodes) Negative regulation of nucleobase-containing compound metabolic process network (Saprolegnia parasitica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPRG_13561	Uncharacterized protein. (170 aa)
	SPRG_18635	Uncharacterized protein. (137 aa)
	SPRG_18159	Uncharacterized protein. (135 aa)
	SPRG_18157	Uncharacterized protein. (199 aa)
	SPRG_17605	Uncharacterized protein. (171 aa)
	SPRG_17316	Uncharacterized protein. (115 aa)
	SPRG_16722	Uncharacterized protein. (173 aa)
	SPRG_21826	MAGE domain-containing protein. (118 aa)
	SPRG_15968	Uncharacterized protein. (177 aa)
	SPRG_21414	Uncharacterized protein. (249 aa)
	SPRG_16819	JmjC domain-containing protein. (589 aa)
	SPRG_15034	Uncharacterized protein. (280 aa)
	SPRG_14837	Uncharacterized protein. (159 aa)
	SPRG_16402	Uncharacterized protein. (226 aa)
	SPRG_14167	Uncharacterized protein. (294 aa)
	SPRG_14836	Uncharacterized protein. (199 aa)
	SPRG_14578	Uncharacterized protein. (351 aa)
	SPRG_14583	Uncharacterized protein. (281 aa)
	SPRG_15970	Uncharacterized protein. (184 aa)
	SPRG_17888	Uncharacterized protein. (150 aa)
	SPRG_13412	Uncharacterized protein. (243 aa)
	SPRG_14100	Uncharacterized protein. (116 aa)
	SPRG_13401	Uncharacterized protein. (197 aa)
	SPRG_13411	Uncharacterized protein. (295 aa)
	SPRG_13430	Uncharacterized protein. (230 aa)
	SPRG_13535	Uncharacterized protein. (173 aa)
	SPRG_17431	Uncharacterized protein. (307 aa)
	SPRG_13548	Uncharacterized protein. (206 aa)
	SPRG_13563	Uncharacterized protein. (216 aa)
	SPRG_12503	Uncharacterized protein. (160 aa)
	SPRG_12527	Uncharacterized protein. (1525 aa)
	SPRG_13562	Uncharacterized protein. (170 aa)
	SPRG_14838	Uncharacterized protein. (121 aa)
	SPRG_13696	PB1 domain-containing protein. (241 aa)
	SPRG_15373	PB1 domain-containing protein. (239 aa)
	SPRG_16887	Uncharacterized protein. (169 aa)
	SPRG_14425	RING-type domain-containing protein. (234 aa)
	SPRG_16537	Uncharacterized protein. (180 aa)
	SPRG_16724	Uncharacterized protein. (199 aa)
	SPRG_22307	HDAC_interact domain-containing protein. (945 aa)
	SPRG_21183	Uncharacterized protein. (263 aa)
	SPRG_15967	Uncharacterized protein. (180 aa)
	SPRG_14101	Uncharacterized protein. (206 aa)
	SPRG_15972	Uncharacterized protein. (195 aa)
	SPRG_12761	Uncharacterized protein. (177 aa)
	SPRG_15971	Uncharacterized protein. (183 aa)
	SPRG_11049	RNA_ligase domain-containing protein. (327 aa)
	SPRG_13549	Uncharacterized protein. (194 aa)
	SPRG_13564	Uncharacterized protein. (183 aa)
	SPRG_11855	Uncharacterized protein. (176 aa)
	SPRG_11820	Uncharacterized protein. (271 aa)
	SPRG_15038	Uncharacterized protein. (1118 aa)
	SPRG_15664	Uncharacterized protein. (517 aa)
	SPRG_21431	Uncharacterized protein. (172 aa)
	SPRG_10740	Uncharacterized protein. (138 aa)
	SPRG_11215	Uncharacterized protein. (236 aa)
	SPRG_12758	Uncharacterized protein. (176 aa)
	SPRG_12762	Uncharacterized protein. (180 aa)
	SPRG_12767	Uncharacterized protein. (282 aa)
	SPRG_10110	Uncharacterized protein. (225 aa)
	SPRG_13410	Uncharacterized protein. (246 aa)
	SPRG_11856	Uncharacterized protein. (217 aa)
	SPRG_10109	Uncharacterized protein. (841 aa)
	SPRG_10129	Uncharacterized protein. (96 aa)
	SPRG_11190	RING-type domain-containing protein. (234 aa)
	SPRG_09572	Uncharacterized protein. (171 aa)
	SPRG_12429	Uncharacterized protein. (192 aa)
	SPRG_10513	Uncharacterized protein. (394 aa)
	SPRG_09376	Hist_deacetyl domain-containing protein. (578 aa)
	SPRG_12466	Uncharacterized protein. (196 aa)
	SPRG_13560	Uncharacterized protein. (197 aa)
	SPRG_13570	Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (293 aa)
	SPRG_13689	PB1 domain-containing protein. (334 aa)
	SPRG_12465	Uncharacterized protein. (176 aa)
	SPRG_09038	Uncharacterized protein. (408 aa)
	SPRG_13356	ANK_REP_REGION domain-containing protein. (684 aa)
	SPRG_12400	Uncharacterized protein. (197 aa)
	SPRG_10422	ANK_REP_REGION domain-containing protein. (346 aa)
	SPRG_10467	Repressor of RNA polymerase III transcription. (229 aa)
	SPRG_12609	Uncharacterized protein. (177 aa)
	SPRG_10095	Uncharacterized protein. (181 aa)
	SPRG_10111	Uncharacterized protein. (178 aa)
	SPRG_10131	Uncharacterized protein. (191 aa)
	SPRG_12738	Uncharacterized protein. (197 aa)
	SPRG_12765	Ig-like domain-containing protein. (195 aa)
	SPRG_09692	Uncharacterized protein. (166 aa)
	SPRG_12547	JmjC domain-containing protein. (576 aa)
	SPRG_08181	Uncharacterized protein. (431 aa)
	SPRG_12759	Uncharacterized protein. (162 aa)
	SPRG_12764	Uncharacterized protein. (171 aa)
	SPRG_08147	Uncharacterized protein. (222 aa)
	SPRG_06954	Uncharacterized protein. (173 aa)
	SPRG_06975	Uncharacterized protein. (204 aa)
	SPRG_11404	Uncharacterized protein. (257 aa)
	SPRG_10529	Uncharacterized protein. (438 aa)
	SPRG_07117	Hist_deacetyl domain-containing protein. (514 aa)
	SPRG_10514	DUF4201 domain-containing protein. (276 aa)
	SPRG_20211	Uncharacterized protein. (246 aa)
	SPRG_07176	Uncharacterized protein. (333 aa)
	SPRG_08075	zf-LYAR domain-containing protein. (278 aa)
	SPRG_06642	Uncharacterized protein. (214 aa)
	SPRG_10128	Uncharacterized protein. (159 aa)
	SPRG_06641	Uncharacterized protein. (230 aa)
	SPRG_10096	Uncharacterized protein. (164 aa)
	SPRG_10112	Uncharacterized protein. (175 aa)
	SPRG_10127	Uncharacterized protein. (125 aa)
	SPRG_06977	Uncharacterized protein. (188 aa)
	SPRG_07123	RING-type domain-containing protein. (213 aa)
	SPRG_07183	Uncharacterized protein. (186 aa)
	SPRG_09077	Uncharacterized protein. (486 aa)
	SPRG_04850	Uncharacterized protein. (172 aa)
	SPRG_04991	ANK_REP_REGION domain-containing protein. (761 aa)
	SPRG_05736	Uncharacterized protein. (197 aa)
	SPRG_04346	Hist_deacetyl domain-containing protein. (430 aa)
	SPRG_08005	Uncharacterized protein. (220 aa)
	SPRG_06035	Uncharacterized protein. (800 aa)
	SPRG_07440	Hist_deacetyl domain-containing protein. (535 aa)
	SPRG_07495	Uncharacterized protein. (350 aa)
	SPRG_06978	Uncharacterized protein. (173 aa)
	SPRG_04762	Uncharacterized protein. (427 aa)
	SPRG_02941	Uncharacterized protein. (434 aa)
	SPRG_19954	Uncharacterized protein. (146 aa)
	SPRG_20010	Uncharacterized protein. (109 aa)
	SPRG_06428	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (463 aa)
	SPRG_06127	Uncharacterized protein. (1536 aa)
	SPRG_05390	E2F_TDP domain-containing protein. (345 aa)
	SPRG_05804	RNA_GG_bind domain-containing protein. (170 aa)
	SPRG_01920	Uncharacterized protein. (114 aa)
	SPRG_02137	Uncharacterized protein. (277 aa)
	SPRG_19899	Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (475 aa)
	SPRG_02033	Uncharacterized protein. (365 aa)
	SPRG_19172	Swi3 domain-containing protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (428 aa)
	SPRG_02136	Uncharacterized protein. (77 aa)
	SPRG_19931	Uncharacterized protein. (171 aa)
	SPRG_19301	Uncharacterized protein. (212 aa)
	SPRG_02433	Uncharacterized protein. (333 aa)
	SPRG_01297	Uncharacterized protein. (145 aa)
	SPRG_01587	Uncharacterized protein. (243 aa)
	SPRG_00933	Uncharacterized protein. (1033 aa)
	SPRG_01127	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (271 aa)
	SPRG_04255	COMM domain-containing protein. (183 aa)
	SPRG_04310	Uncharacterized protein. (374 aa)
	SPRG_01238	Uncharacterized protein. (148 aa)
	SPRG_03443	Uncharacterized protein. (179 aa)
	SPRG_01279	Uncharacterized protein. (194 aa)
	SPRG_01299	Uncharacterized protein. (145 aa)
	SPRG_04036	Uncharacterized protein. (211 aa)
	SPRG_03520	Uncharacterized protein. (253 aa)
	SPRG_01584	Uncharacterized protein. (254 aa)
	SPRG_03686	Uncharacterized protein. (754 aa)
	SPRG_00405	C2H2-type domain-containing protein. (370 aa)
	SPRG_00417	Uncharacterized protein. (1028 aa)
	SPRG_02263	Uncharacterized protein. (511 aa)
	SPRG_19231	Uncharacterized protein. (501 aa)
	SPRG_01382	Uncharacterized protein. (429 aa)
	SPRG_01387	Uncharacterized protein. (251 aa)
	SPRG_01586	Uncharacterized protein. (239 aa)
	SPRG_01033	WD_REPEATS_REGION domain-containing protein. (437 aa)
	SPRG_18837	Deacetylase sirtuin-type domain-containing protein. (309 aa)
	SPRG_00406	Uncharacterized protein. (324 aa)

Your Current Organism:

Saprolegnia parasitica

NCBI taxonomy Id: 695850
Other names: S. parasitica CBS 223.65, Saprolegnia parasitica CBS 223.65

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPRG_00933	SPRG_19172	A0A067CWJ2	A0A067CS53	Uncharacterized protein.	Swi3 domain-containing protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.998
SPRG_01127	SPRG_01382	A0A067CX29	A0A067D5Z2	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.483
SPRG_01127	SPRG_02263	A0A067CX29	A0A067D3X6	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.954
SPRG_01127	SPRG_04346	A0A067CX29	A0A067CI66	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Hist_deacetyl domain-containing protein.	0.483
SPRG_01127	SPRG_04762	A0A067CX29	A0A067CNP5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.623
SPRG_01127	SPRG_04991	A0A067CX29	A0A067CHL5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	ANK_REP_REGION domain-containing protein.	0.483
SPRG_01127	SPRG_06127	A0A067CX29	A0A067CQI2	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.483
SPRG_01127	SPRG_06641	A0A067CX29	A0A067CD23	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.483
SPRG_01127	SPRG_06642	A0A067CX29	A0A067CCB3	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.483
SPRG_01127	SPRG_07117	A0A067CX29	A0A067CAQ2	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Hist_deacetyl domain-containing protein.	0.483
SPRG_01127	SPRG_07440	A0A067CX29	A0A067CKY5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Hist_deacetyl domain-containing protein.	0.483
SPRG_01127	SPRG_09376	A0A067CX29	A0A067C3R5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Hist_deacetyl domain-containing protein.	0.483
SPRG_01127	SPRG_10514	A0A067CX29	A0A067CB44	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	DUF4201 domain-containing protein.	0.483
SPRG_01127	SPRG_11820	A0A067CX29	A0A067BXF6	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.483
SPRG_01127	SPRG_13356	A0A067CX29	A0A067C4R7	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	ANK_REP_REGION domain-containing protein.	0.483
SPRG_01127	SPRG_14167	A0A067CX29	A0A067BND4	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.483
SPRG_01127	SPRG_18157	A0A067CX29	A0A067BDX9	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.483
SPRG_01127	SPRG_18159	A0A067CX29	A0A067BD78	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.483
SPRG_01279	SPRG_10110	A0A067CXK7	A0A067C1C5	Uncharacterized protein.	Uncharacterized protein.	0.528
SPRG_01279	SPRG_12465	A0A067CXK7	A0A067C4L3	Uncharacterized protein.	Uncharacterized protein.	0.535