(62 nodes) Cytoplasmic vesicle membrane network (Saprolegnia parasitica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPRG_22385	Uncharacterized protein; Belongs to the CDC50/LEM3 family. (366 aa)
	SPRG_18291	Uncharacterized protein. (418 aa)
	SPRG_21906	Uncharacterized protein. (180 aa)
	SPRG_17088	Uncharacterized protein; Belongs to the CDC50/LEM3 family. (408 aa)
	SPRG_18497	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family. (161 aa)
	SPRG_16665	Uncharacterized protein. (859 aa)
	SPRG_21790	ABC transmembrane type-1 domain-containing protein. (684 aa)
	SPRG_17641	PX domain-containing protein. (143 aa)
	SPRG_17541	IPPc domain-containing protein. (619 aa)
	SPRG_09486	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (143 aa)
	SPRG_14187	C2 domain-containing protein. (1096 aa)
	SPRG_21420	Uncharacterized protein. (783 aa)
	SPRG_12914	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family. (185 aa)
	SPRG_12050	C2 domain-containing protein. (635 aa)
	SPRG_13436	WD_REPEATS_REGION domain-containing protein. (166 aa)
	SPRG_11633	WD_REPEATS_REGION domain-containing protein. (1190 aa)
	SPRG_13179	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (154 aa)
	SPRG_10492	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (921 aa)
	SPRG_14975	Uncharacterized protein. (218 aa)
	SPRG_12560	Uncharacterized protein. (97 aa)
	SPRG_10875	Uncharacterized protein. (156 aa)
	SPRG_13433	WD_REPEATS_REGION domain-containing protein. (691 aa)
	SPRG_10800	PX domain-containing protein. (587 aa)
	SPRG_08752	Cytochrome b561 domain-containing protein. (266 aa)
	SPRG_08445	Uncharacterized protein. (916 aa)
	SPRG_11709	Uncharacterized protein; Belongs to the CDC50/LEM3 family. (401 aa)
	SPRG_08276	Uncharacterized protein. (711 aa)
	SPRG_11708	Uncharacterized protein; Belongs to the CDC50/LEM3 family. (408 aa)
	SPRG_07687	Cytochrome b561 domain-containing protein. (268 aa)
	SPRG_07508	PX domain-containing protein. (126 aa)
	SPRG_08827	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (517 aa)
	SPRG_07502	Uncharacterized protein. (1103 aa)
	SPRG_10648	Uncharacterized protein. (4924 aa)
	SPRG_10669	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (864 aa)
	SPRG_10026	Uncharacterized protein. (217 aa)
	SPRG_09873	Uncharacterized protein. (798 aa)
	SPRG_06878	Uncharacterized protein. (477 aa)
	SPRG_06719	PA domain-containing protein. (577 aa)
	SPRG_05270	Uncharacterized protein. (815 aa)
	SPRG_05244	IPPc domain-containing protein. (873 aa)
	SPRG_05365	Uncharacterized protein. (1027 aa)
	SPRG_04406	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (133 aa)
	SPRG_06834	Uncharacterized protein. (1045 aa)
	SPRG_05286	Uncharacterized protein. (1003 aa)
	SPRG_07353	Vps53_N domain-containing protein. (827 aa)
	SPRG_02206	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1083 aa)
	SPRG_05624	AP-1 complex subunit gamma. (827 aa)
	SPRG_19275	DUF1681 domain-containing protein. (207 aa)
	SPRG_19095	WD_REPEATS_REGION domain-containing protein. (1021 aa)
	SPRG_05042	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (162 aa)
	SPRG_01573	DUF1681 domain-containing protein. (252 aa)
	SPRG_03840	PA domain-containing protein. (640 aa)
	SPRG_03943	Uncharacterized protein. (652 aa)
	SPRG_04004	ENTH domain-containing protein. (594 aa)
	SPRG_00203	Uncharacterized protein. (608 aa)
	SPRG_00886	Uncharacterized protein. (286 aa)
	SPRG_02372	NPC1_N domain-containing protein. (352 aa)
	SPRG_01861	IPPc domain-containing protein. (586 aa)
	SPRG_01787	Uncharacterized protein; Belongs to the CDC50/LEM3 family. (415 aa)
	SPRG_01301	SSD domain-containing protein. (955 aa)
	SPRG_00540	Uncharacterized protein. (459 aa)
	SPRG_00205	SSD domain-containing protein. (1376 aa)

Your Current Organism:

Saprolegnia parasitica

NCBI taxonomy Id: 695850
Other names: S. parasitica CBS 223.65, Saprolegnia parasitica CBS 223.65

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPRG_00886	SPRG_10669	A0A067CZZ0	A0A067CAX2	Uncharacterized protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.451
SPRG_00886	SPRG_13433	A0A067CZZ0	A0A067C2D6	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.694
SPRG_00886	SPRG_13436	A0A067CZZ0	A0A067BV56	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.694
SPRG_01573	SPRG_05624	A0A067CV88	A0A067CSD5	DUF1681 domain-containing protein.	AP-1 complex subunit gamma.	0.732
SPRG_01573	SPRG_09486	A0A067CV88	A0A067BMG7	DUF1681 domain-containing protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.824
SPRG_01573	SPRG_10492	A0A067CV88	A0A067BYZ6	DUF1681 domain-containing protein.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.895
SPRG_01573	SPRG_10648	A0A067CV88	A0A067CAV4	DUF1681 domain-containing protein.	Uncharacterized protein.	0.501
SPRG_01861	SPRG_08276	A0A067D2R2	A0A067C7H4	IPPc domain-containing protein.	Uncharacterized protein.	0.906
SPRG_01861	SPRG_17541	A0A067D2R2	A0A067BJV7	IPPc domain-containing protein.	IPPc domain-containing protein.	0.900
SPRG_02206	SPRG_05042	A0A067CRQ6	A0A067CUY2	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.983
SPRG_02206	SPRG_05624	A0A067CRQ6	A0A067CSD5	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	AP-1 complex subunit gamma.	0.890
SPRG_02206	SPRG_10492	A0A067CRQ6	A0A067BYZ6	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.874
SPRG_04004	SPRG_05624	A0A067CX56	A0A067CSD5	ENTH domain-containing protein.	AP-1 complex subunit gamma.	0.764
SPRG_04004	SPRG_10492	A0A067CX56	A0A067BYZ6	ENTH domain-containing protein.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.667
SPRG_05042	SPRG_02206	A0A067CUY2	A0A067CRQ6	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.983
SPRG_05042	SPRG_05624	A0A067CUY2	A0A067CSD5	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-1 complex subunit gamma.	0.962
SPRG_05042	SPRG_09486	A0A067CUY2	A0A067BMG7	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.412
SPRG_05042	SPRG_10492	A0A067CUY2	A0A067BYZ6	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.938
SPRG_05042	SPRG_10875	A0A067CUY2	A0A067C0N7	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Uncharacterized protein.	0.975
SPRG_05270	SPRG_06834	A0A067CH61	A0A067CL84	Uncharacterized protein.	Uncharacterized protein.	0.979