(12 nodes) TBP domain superfamily network (Saprolegnia parasitica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPRG_10492	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (921 aa)
	SPRG_05126	Uncharacterized protein. (198 aa)
	SPRG_01590	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (888 aa)
	SPRG_19892	Uncharacterized protein. (213 aa)
	SPRG_03957	AP complex subunit beta. (907 aa)
	SPRG_03180	Uncharacterized protein. (225 aa)
	SPRG_07485	B2-adapt-app_C domain-containing protein. (385 aa)
	SPRG_19532	AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (708 aa)
	SPRG_05214	Uncharacterized protein. (632 aa)
	SPRG_04961	FHA domain-containing protein. (802 aa)
	SPRG_18284	Uncharacterized protein. (634 aa)
	SPRG_14897	B2-adapt-app_C domain-containing protein. (774 aa)

Your Current Organism:

Saprolegnia parasitica

NCBI taxonomy Id: 695850
Other names: S. parasitica CBS 223.65, Saprolegnia parasitica CBS 223.65

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPRG_01590	SPRG_03957	A0A067CSL0	A0A067CQ20	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	AP complex subunit beta.	0.565
SPRG_01590	SPRG_19532	A0A067CSL0	A0A067CKK8	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.565
SPRG_03180	SPRG_05126	A0A067CMN4	A0A067CTR8	Uncharacterized protein.	Uncharacterized protein.	0.908
SPRG_03180	SPRG_19892	A0A067CMN4	A0A067CR15	Uncharacterized protein.	Uncharacterized protein.	0.905
SPRG_03957	SPRG_01590	A0A067CQ20	A0A067CSL0	AP complex subunit beta.	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.565
SPRG_03957	SPRG_10492	A0A067CQ20	A0A067BYZ6	AP complex subunit beta.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.985
SPRG_03957	SPRG_19532	A0A067CQ20	A0A067CKK8	AP complex subunit beta.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.412
SPRG_05126	SPRG_03180	A0A067CTR8	A0A067CMN4	Uncharacterized protein.	Uncharacterized protein.	0.908
SPRG_05126	SPRG_19892	A0A067CTR8	A0A067CR15	Uncharacterized protein.	Uncharacterized protein.	0.910
SPRG_10492	SPRG_03957	A0A067BYZ6	A0A067CQ20	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP complex subunit beta.	0.985
SPRG_10492	SPRG_19532	A0A067BYZ6	A0A067CKK8	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.985
SPRG_19532	SPRG_01590	A0A067CKK8	A0A067CSL0	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.565
SPRG_19532	SPRG_03957	A0A067CKK8	A0A067CQ20	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	AP complex subunit beta.	0.412
SPRG_19532	SPRG_10492	A0A067CKK8	A0A067BYZ6	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.985
SPRG_19892	SPRG_03180	A0A067CR15	A0A067CMN4	Uncharacterized protein.	Uncharacterized protein.	0.905
SPRG_19892	SPRG_05126	A0A067CR15	A0A067CTR8	Uncharacterized protein.	Uncharacterized protein.	0.910