(89 nodes) Ubiquitin mediated proteolysis network (Saprolegnia parasitica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPRG_18394	Uncharacterized protein. (394 aa)
	SPRG_18112	Uncharacterized protein. (602 aa)
	SPRG_17665	WD_REPEATS_REGION domain-containing protein. (465 aa)
	SPRG_17573	Uncharacterized protein; Belongs to the SKP1 family. (156 aa)
	SPRG_17025	Uncharacterized protein. (1019 aa)
	SPRG_15526	Uncharacterized protein. (4533 aa)
	SPRG_14675	VPS9 domain-containing protein. (787 aa)
	SPRG_13457	WD_REPEATS_REGION domain-containing protein. (630 aa)
	SPRG_13325	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (161 aa)
	SPRG_17525	Uncharacterized protein. (375 aa)
	SPRG_12074	Ubiquitin-40S ribosomal protein S27a. (154 aa)
	SPRG_16444	Uncharacterized protein. (629 aa)
	SPRG_16305	Uncharacterized protein. (554 aa)
	SPRG_21096	Uncharacterized protein. (3963 aa)
	SPRG_12020	UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family. (978 aa)
	SPRG_13360	Uncharacterized protein. (427 aa)
	SPRG_13376	Uncharacterized protein. (743 aa)
	SPRG_15029	Ribosomal_L40e domain-containing protein. (64 aa)
	SPRG_15523	Uncharacterized protein. (4153 aa)
	SPRG_14896	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
	SPRG_12726	HECT domain-containing protein. (1089 aa)
	SPRG_10038	HECT domain-containing protein. (428 aa)
	SPRG_11712	Uncharacterized protein. (561 aa)
	SPRG_22263	Uncharacterized protein. (765 aa)
	SPRG_14189	Uncharacterized protein. (3412 aa)
	SPRG_12152	WD_REPEATS_REGION domain-containing protein. (454 aa)
	SPRG_13995	Uncharacterized protein. (475 aa)
	SPRG_13450	Ubiquitin-like domain-containing protein. (156 aa)
	SPRG_11563	Uncharacterized protein. (614 aa)
	SPRG_11649	Uncharacterized protein. (702 aa)
	SPRG_11654	RING-type domain-containing protein. (102 aa)
	SPRG_11296	E2_bind domain-containing protein. (458 aa)
	SPRG_20641	TPR_REGION domain-containing protein. (556 aa)
	SPRG_11729	Uncharacterized protein. (510 aa)
	SPRG_11463	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (103 aa)
	SPRG_07036	UBIQUITIN_CONJUGAT_2 domain-containing protein. (183 aa)
	SPRG_10067	WD_REPEATS_REGION domain-containing protein. (416 aa)
	SPRG_10819	Ribosomal_L40e domain-containing protein. (56 aa)
	SPRG_09929	WD_REPEATS_REGION domain-containing protein. (543 aa)
	SPRG_06757	WD_REPEATS_REGION domain-containing protein. (518 aa)
	SPRG_07658	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (216 aa)
	SPRG_07766	Uncharacterized protein. (3985 aa)
	SPRG_05703	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (175 aa)
	SPRG_09684	Uncharacterized protein. (606 aa)
	SPRG_09689	Uncharacterized protein. (558 aa)
	SPRG_20000	ThiF domain-containing protein. (320 aa)
	SPRG_07108	HECT domain-containing protein. (815 aa)
	SPRG_05163	Ubiquitin-conjugating enzyme E2 4; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	SPRG_08828	CULLIN_2 domain-containing protein; Belongs to the cullin family. (755 aa)
	SPRG_20606	Uncharacterized protein. (1763 aa)
	SPRG_05069	SAP domain-containing protein. (578 aa)
	SPRG_05099	Uncharacterized protein; Belongs to the SKP1 family. (161 aa)
	SPRG_04386	Uncharacterized protein. (275 aa)
	SPRG_19683	Uncharacterized protein. (574 aa)
	SPRG_03812	Uncharacterized protein. (651 aa)
	SPRG_06789	Ubiquitin-like domain-containing protein. (98 aa)
	SPRG_04038	CPSF_A domain-containing protein. (946 aa)
	SPRG_07085	SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family. (585 aa)
	SPRG_06240	RING-type domain-containing protein. (664 aa)
	SPRG_03371	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
	SPRG_06670	UBIQUITIN_CONJUGAT_2 domain-containing protein. (230 aa)
	SPRG_02670	Uncharacterized protein. (1349 aa)
	SPRG_03565	RING-type domain-containing protein. (368 aa)
	SPRG_05824	Uncharacterized protein; Belongs to the SKP1 family. (156 aa)
	SPRG_03680	UBIQUITIN_CONJUGAT_2 domain-containing protein. (301 aa)
	SPRG_05913	ThiF domain-containing protein. (578 aa)
	SPRG_03381	HECT domain-containing protein. (692 aa)
	SPRG_02917	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family. (195 aa)
	SPRG_01784	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (173 aa)
	SPRG_05334	Uncharacterized protein; Belongs to the SKP1 family. (168 aa)
	SPRG_01778	Uncharacterized protein. (282 aa)
	SPRG_02351	UBIQUITIN_CONJUGAT_2 domain-containing protein. (214 aa)
	SPRG_02553	U-box domain-containing protein. (993 aa)
	SPRG_02628	Uncharacterized protein. (668 aa)
	SPRG_19786	Uncharacterized protein. (1352 aa)
	SPRG_04568	HECT domain-containing protein. (1411 aa)
	SPRG_00692	WD_REPEATS_REGION domain-containing protein. (516 aa)
	SPRG_00695	TPR_REGION domain-containing protein. (627 aa)
	SPRG_04632	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
	SPRG_01077	CULLIN_2 domain-containing protein; Belongs to the cullin family. (744 aa)
	SPRG_00198	CULLIN_2 domain-containing protein; Belongs to the cullin family. (673 aa)
	SPRG_00222	TPR_REGION domain-containing protein. (1030 aa)
	SPRG_19544	Uncharacterized protein. (75 aa)
	SPRG_00468	WD_REPEATS_REGION domain-containing protein. (389 aa)
	SPRG_00337	Uncharacterized protein. (1140 aa)
	SPRG_01620	Anaphase-promoting complex subunit 11. (86 aa)
	SPRG_01614	CULLIN_2 domain-containing protein; Belongs to the cullin family. (742 aa)
	SPRG_01820	Uncharacterized protein. (562 aa)
	SPRG_18828	Uncharacterized protein. (423 aa)

Your Current Organism:

Saprolegnia parasitica

NCBI taxonomy Id: 695850
Other names: S. parasitica CBS 223.65, Saprolegnia parasitica CBS 223.65

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPRG_00198	SPRG_00695	A0A067CXC3	A0A067CVV8	CULLIN_2 domain-containing protein; Belongs to the cullin family.	TPR_REGION domain-containing protein.	0.999
SPRG_00198	SPRG_01614	A0A067CXC3	A0A067D4M1	CULLIN_2 domain-containing protein; Belongs to the cullin family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.434
SPRG_00198	SPRG_01620	A0A067CXC3	A0A067D3W6	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Anaphase-promoting complex subunit 11.	0.999
SPRG_00198	SPRG_01784	A0A067CXC3	A0A067CT66	CULLIN_2 domain-containing protein; Belongs to the cullin family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.633
SPRG_00198	SPRG_02917	A0A067CXC3	A0A067CT53	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family.	0.617
SPRG_00198	SPRG_03371	A0A067CXC3	A0A067CN84	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.	0.617
SPRG_00198	SPRG_03680	A0A067CXC3	A0A067CRA0	CULLIN_2 domain-containing protein; Belongs to the cullin family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.653
SPRG_00198	SPRG_04632	A0A067CXC3	A0A067CW50	CULLIN_2 domain-containing protein; Belongs to the cullin family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.650
SPRG_00198	SPRG_05163	A0A067CXC3	A0A067CGT5	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Ubiquitin-conjugating enzyme E2 4; Belongs to the ubiquitin-conjugating enzyme family.	0.633
SPRG_00198	SPRG_05703	A0A067CXC3	A0A067CDF0	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.	0.965
SPRG_00198	SPRG_06757	A0A067CXC3	A0A067CBX8	CULLIN_2 domain-containing protein; Belongs to the cullin family.	WD_REPEATS_REGION domain-containing protein.	0.841
SPRG_00198	SPRG_06789	A0A067CXC3	A0A067CL34	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Ubiquitin-like domain-containing protein.	0.756
SPRG_00198	SPRG_09929	A0A067CXC3	A0A067CBV8	CULLIN_2 domain-containing protein; Belongs to the cullin family.	WD_REPEATS_REGION domain-containing protein.	0.841
SPRG_00198	SPRG_10819	A0A067CXC3	A0A067CBV7	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Ribosomal_L40e domain-containing protein.	0.756
SPRG_00198	SPRG_11296	A0A067CXC3	A0A067C3Z6	CULLIN_2 domain-containing protein; Belongs to the cullin family.	E2_bind domain-containing protein.	0.595
SPRG_00198	SPRG_11649	A0A067CXC3	A0A067C2G7	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Uncharacterized protein.	0.999
SPRG_00198	SPRG_11654	A0A067CXC3	A0A067C2H1	CULLIN_2 domain-containing protein; Belongs to the cullin family.	RING-type domain-containing protein.	0.602
SPRG_00198	SPRG_11712	A0A067CXC3	A0A067C086	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Uncharacterized protein.	0.983
SPRG_00198	SPRG_12074	A0A067CXC3	A0A067BUZ0	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Ubiquitin-40S ribosomal protein S27a.	0.756
SPRG_00198	SPRG_13325	A0A067CXC3	A0A067BR81	CULLIN_2 domain-containing protein; Belongs to the cullin family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.617