(16 nodes) Fatty acid metabolism network (Bartonella clarridgeiae)

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	accD	acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (301 aa)
	fabI	Enoyl-[acyl-carrier-protein] reductase. (279 aa)
	fabB	3-oxoacyl-(acyl-carrier-protein) synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (406 aa)
	fabA	3-hydroxydecanoyl-[acyl-carrier- protein]dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (169 aa)
	fabI-2	Enoyl-[acyl-carrier-protein ] reductase. (272 aa)
	fabD	Malonyl CoA-acyl carrier protein transacylase. (314 aa)
	fabG	3-oxoacyl-(acyl carrierprotein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa)
	fabF	3-oxoacyl-acyl carrier protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (420 aa)
	accC	Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (452 aa)
	accB	Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (159 aa)
	fabH	Acyl-carrier-protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (323 aa)
	acpP-2	Acyl carrier protein. (94 aa)
	BARCL_0837	Beta-ketoacyl synthase family protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (391 aa)
	fabF-2	3-oxoacyl-(acyl-carrier-protein) synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (425 aa)
	adh	Alcohol dehydrogenase. (342 aa)
	accA	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)

Your Current Organism:

Bartonella clarridgeiae

NCBI taxonomy Id: 696125
Other names: B. clarridgeiae 73, Bartonella clarridgeiae 73, Bartonella clarridgeiae str. 73, Bartonella clarridgeiae strain 73

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BARCL_0837	accA	BARCL_0837	BARCL_1353	Beta-ketoacyl synthase family protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	0.644
BARCL_0837	accD	BARCL_0837	BARCL_0041	Beta-ketoacyl synthase family protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.	0.630
BARCL_0837	acpP-2	BARCL_0837	BARCL_0836	Beta-ketoacyl synthase family protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Acyl carrier protein.	0.982
BARCL_0837	adh	BARCL_0837	BARCL_0839	Beta-ketoacyl synthase family protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Alcohol dehydrogenase.	0.902
BARCL_0837	fabA	BARCL_0837	BARCL_0141	Beta-ketoacyl synthase family protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	3-hydroxydecanoyl-[acyl-carrier- protein]dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.	0.707
BARCL_0837	fabB	BARCL_0837	BARCL_0140	Beta-ketoacyl synthase family protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	3-oxoacyl-(acyl-carrier-protein) synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.912
BARCL_0837	fabD	BARCL_0837	BARCL_0549	Beta-ketoacyl synthase family protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Malonyl CoA-acyl carrier protein transacylase.	0.974
BARCL_0837	fabF	BARCL_0837	BARCL_0552	Beta-ketoacyl synthase family protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	3-oxoacyl-acyl carrier protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.	0.903
BARCL_0837	fabF-2	BARCL_0837	BARCL_0838	Beta-ketoacyl synthase family protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	3-oxoacyl-(acyl-carrier-protein) synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.992
BARCL_0837	fabG	BARCL_0837	BARCL_0550	Beta-ketoacyl synthase family protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	3-oxoacyl-(acyl carrierprotein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.945
BARCL_0837	fabH	BARCL_0837	BARCL_0819	Beta-ketoacyl synthase family protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Acyl-carrier-protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.	0.966
BARCL_0837	fabI	BARCL_0837	BARCL_0139	Beta-ketoacyl synthase family protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Enoyl-[acyl-carrier-protein] reductase.	0.956
BARCL_0837	fabI-2	BARCL_0837	BARCL_0426	Beta-ketoacyl synthase family protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Enoyl-[acyl-carrier-protein ] reductase.	0.956
accA	BARCL_0837	BARCL_1353	BARCL_0837	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	Beta-ketoacyl synthase family protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.644
accA	accB	BARCL_1353	BARCL_0805	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.996
accA	accC	BARCL_1353	BARCL_0804	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.982
accA	accD	BARCL_1353	BARCL_0041	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.	0.999
accA	fabA	BARCL_1353	BARCL_0141	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	3-hydroxydecanoyl-[acyl-carrier- protein]dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.	0.658
accA	fabB	BARCL_1353	BARCL_0140	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	3-oxoacyl-(acyl-carrier-protein) synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.647
accA	fabD	BARCL_1353	BARCL_0549	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	Malonyl CoA-acyl carrier protein transacylase.	0.964