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| | BARCL_0904 | ATP12 chaperone family protein. (264 aa) |
| | BARCL_0016 | Homologs of previously reported genes of unknown function. (215 aa) |
| | BARCL_0034 | Putative ATP-dependent nuclease subunit A; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the helicase family. UvrD subfamily. (1152 aa) |
| | folC | Dihydrofolate synthase / folylpolyglutamate synthase; Function of strongly homologous gene; enzyme; Belongs to the folylpolyglutamate synthase family. (434 aa) |
| | gyrB | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (809 aa) |
| | BARCL_0048 | Homologs of previously reported genes of unknown function. (510 aa) |
| | rplT | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (133 aa) |
| | secB | Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (158 aa) |
| | BARCL_0124 | Thiol:disulfide interchange protein (fragment). (128 aa) |
| | ccmD | Heme exporter protein CcmD. (83 aa) |
| | ccmC | Heme exporter protein C; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (257 aa) |
| | ccmB | Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (221 aa) |
| | ccmA | Cytochrome c biogenesis ATP-binding export protein ccmA (Heme exporter protein A); Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (206 aa) |
| | BARCL_0189 | Homologs of previously reported genes of unknown function. (285 aa) |
| | cgpA | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (213 aa) |
| | mrp | ATP/GTP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (378 aa) |
| | BARCL_0292 | Homologs of previously reported genes of unknown function. (215 aa) |
| | BARCL_0360 | Homologs of previously reported genes of unknown function. (268 aa) |
| | BARCL_0373 | Homologs of previously reported genes of unknown function. (492 aa) |
| | BARCL_0377 | Homologs of previously reported genes of unknown function. (136 aa) |
| | BARCL_0387 | Cytochrome c-type biogenesis protein (fragment). (165 aa) |
| | ccmE | Cytochrome c-type biogenesis protein ccmE (Cytochrome c maturation protein E) (Heme chaperone ccmE); Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. (165 aa) |
| | cycK | Cytochrome C-type biogenesis protein. (657 aa) |
| | ccmH | Cytochrome c-type biogenesis protein ccmH precursor (Cytochrome c-type biogenesis protein cycL); Possible subunit of a heme lyase. (143 aa) |
| | BARCL_0437 | NifU-related protein. (196 aa) |
| | mviN | MviN protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (520 aa) |
| | flhA | Flagellar biosynthesis protein flhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (699 aa) |
| | fliR | Flagellar biosynthetic protein FliR. (259 aa) |
| | BARCL_0447 | Homologs of previously reported genes of unknown function. (172 aa) |
| | BARCL_0448 | Homologs of previously reported genes of unknown function. (147 aa) |
| | flhB | Flagellar biosynthetic protein flhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (356 aa) |
| | flgA | Flagella basal body P-ring formation protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family. (152 aa) |
| | BARCL_0468 | Homologs of previously reported genes of unknown function. (238 aa) |
| | fliP | Flagellar biosynthetic protein fliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (250 aa) |
| | BARCL_0481 | Putative flagellar motor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (408 aa) |
| | flgK | Flagellar hook-associated protein FlgK. (456 aa) |
| | flaF | Flaf protein. (122 aa) |
| | BARCL_0489 | Flagellar hook capping protein (fragment). (169 aa) |
| | fliQ | Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (88 aa) |
| | dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (499 aa) |
| | mltG | Conserved protein of unknown function; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (369 aa) |
| | surA | Peptidyl-prolyl cis-trans isomerase. (319 aa) |
| | lptD | Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. (786 aa) |
| | BARCL_0609 | DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (92 aa) |
| | BARCL_0614 | Homologs of previously reported genes of unknown function. (132 aa) |
| | gyrA | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (923 aa) |
| | BARCL_0673 | Homologs of previously reported genes of unknown function; Belongs to the HesB/IscA family. (107 aa) |
| | ccdA | Cytochrome c-type biogenesis protein. (262 aa) |
| | glmU | Glucosamine-1-phosphate N-acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (449 aa) |
| | recG | ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (701 aa) |
| | parC | Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (749 aa) |
| | BARCL_0699 | Homologs of previously reported genes of unknown function. (109 aa) |
| | parE | Topoisomerase protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (692 aa) |
| | sufB | ABC transporter subunit. (503 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (863 aa) |
| | BARCL_0813 | Homologs of previously reported genes of unknown function. (145 aa) |
| | BARCL_0814 | Conserved protein of unknown function; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. (114 aa) |
| | BARCL_0822 | Small protein A. (175 aa) |
| | ribE | Riboflavin synthase alpha chain. (205 aa) |
| | mazG-2 | Fragment of MazG protein (part 2); Belongs to the HesB/IscA family. (125 aa) |
| | bamA | Outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (798 aa) |
| | rrf | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (186 aa) |
| | BARCL_0882 | Homologs of previously reported genes of unknown function. (270 aa) |
| | dacD | Penicillin-binding protein; Belongs to the peptidase S11 family. (449 aa) |
| | uvrD | DNA helicase II. (817 aa) |
| | comL | Competence lipoprotein precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (306 aa) |
| | ftsZ | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (581 aa) |
| | ftsQ | Cell division protein ftsQ homolog; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. (305 aa) |
| | ddlB | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (306 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (325 aa) |
| | murC | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (456 aa) |
| | murG | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (370 aa) |
| | murD | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (471 aa) |
| | mraY | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (356 aa) |
| | murF | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diamin opimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (473 aa) |
| | murE | UDP-N-acetylmuramoylalanyl-D-glutamate--2,6 diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (483 aa) |
| | BARCL_1008 | Transmembrane protein. (172 aa) |
| | prfA | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (357 aa) |
| | typA | GTP-binding protein TypA. (607 aa) |
| | rsfS | Conserved protein of unknown function; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (120 aa) |
| | BARCL_1174 | Homologs of previously reported genes of unknown function. (487 aa) |
| | murA | UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (430 aa) |
| | BARCL_1203 | Protein of unknown function; No homology to any previously reported sequences. (666 aa) |
| | ruvA | Holliday junction ATP-dependent DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (213 aa) |
| | ruvB | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (364 aa) |
| | BARCL_1246 | Conserved protein of unknown function; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (129 aa) |
| | mtgA | Monofunctional biosynthetic peptidoglycan transglycosylase (Monofunctional TGase); Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (222 aa) |
| | priA | Primosomal replication factor Y; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (739 aa) |
| | BARCL_1278 | Homologs of previously reported genes of unknown function. (196 aa) |
| | BARCL_1327 | Homologs of previously reported genes of unknown function. (389 aa) |
| | BARCL_1329 | Antioxidant, AhpC/TSA family. (233 aa) |
| | dacD-2 | Penicillin-binding protein; Belongs to the peptidase S11 family. (367 aa) |
| | sufC | ABC transporter ATP-binding protein. (251 aa) |
| | sufD | ABC-type transport system. (422 aa) |
| | BARCL_0769 | Homologs of previously reported genes of unknown function. (133 aa) |
| | dacA | Penicillin-binding protein; Belongs to the peptidase S11 family. (394 aa) |
| | rlpA | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (239 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (273 aa) |
| | prfB | Peptide chain release factor RF-2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (333 aa) |
| | mfd | Transcription repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1166 aa) |
| | lemA | Membrane protein LemA. (215 aa) |
