STRINGSTRING
ppk ppk BARCL_0602 BARCL_0602 pdhC pdhC eno eno tpiA tpiA ndk ndk BARCL_1356 BARCL_1356 BARCL_1251 BARCL_1251 pgk pgk tktA tktA BARCL_1357 BARCL_1357 fbaB fbaB BARCL_1162 BARCL_1162 gmk gmk spoT spoT BARCL_0503 BARCL_0503 ribF ribF thiD thiD BARCL_0398 BARCL_0398 BARCL_0394 BARCL_0394 feuQ feuQ ppdK ppdK BARCL_0362 BARCL_0362 envZ envZ prsA prsA BARCL_0294 BARCL_0294 gpmA gpmA pgi pgi BARCL_0226 BARCL_0226 lpxK lpxK coaA coaA cmk cmk argB argB batS batS BARCL_0037 BARCL_0037 coaE coaE BARCL_0001 BARCL_0001 BARCL_1158 BARCL_1158 proB proB lysC lysC ipk ipk BARCL_1018 BARCL_1018 BARCL_0977 BARCL_0977 adk adk BARCL_0884 BARCL_0884 pyrH pyrH nadK nadK tmk tmk BARCL_0700 BARCL_0700
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (711 aa)
BARCL_0602Two-component system, sensor histidine kinase. (756 aa)
pdhCDihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (441 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (422 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (254 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
BARCL_1356Shikimate kinase (SK) (fragment). (143 aa)
BARCL_1251Homologs of previously reported genes of unknown function. (227 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (407 aa)
tktATransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (666 aa)
BARCL_1357Shikimate kinase (SK) (fragment). (59 aa)
fbaBFructose-bisphosphate aldolase. (343 aa)
BARCL_1162Two-component system sensor histidine kinase. (333 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (221 aa)
spoTGTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (742 aa)
BARCL_0503Homologs of previously reported genes of unknown function; Belongs to the UPF0434 family. (64 aa)
ribFRiboflavin biosynthesis protein RibF; Belongs to the ribF family. (330 aa)
thiDPhosphomethylpyrimidine kinase. (249 aa)
BARCL_0398Two-component sensor histidine kinase. (769 aa)
BARCL_0394Sensor histidine kinase. (463 aa)
feuQSensor histidine kinase. (469 aa)
ppdKPyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (899 aa)
BARCL_0362Homologs of previously reported genes of unknown function. (961 aa)
envZSensor histidine kinase. (446 aa)
prsARibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa)
BARCL_0294Homologs of previously reported genes of unknown function. (212 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (206 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (548 aa)
BARCL_0226Homologs of previously reported genes of unknown function. (474 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (340 aa)
coaAPantothenate kinase. (332 aa)
cmkCytidylate kinase. (215 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (301 aa)
batSTwo-component sensor kinase BatS. (590 aa)
BARCL_0037Putative sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (825 aa)
coaEFragment of Shikimate 5-dehydrogenase (part 2); Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa)
BARCL_0001Conserved protein of unknown function; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (277 aa)
BARCL_1158Homologs of previously reported genes of unknown function. (472 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (377 aa)
lysCAspartokinase, alpha and beta subunits; Belongs to the aspartokinase family. (416 aa)
ipk4-diphosphocytidyl-2-C-methyl-D- erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (302 aa)
BARCL_1018Protein of unknown function; No homology to any previously reported sequences. (82 aa)
BARCL_0977Homologs of previously reported genes of unknown function. (181 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (197 aa)
BARCL_0884HIT family protein. (140 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (238 aa)
nadKPutative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (257 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (210 aa)
BARCL_0700Sensor histidine kinase. (854 aa)
Your Current Organism:
Bartonella clarridgeiae
NCBI taxonomy Id: 696125
Other names: B. clarridgeiae 73, Bartonella clarridgeiae 73, Bartonella clarridgeiae str. 73, Bartonella clarridgeiae strain 73
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