(17 nodes) ACT domain network (Desulfotomaculum ruminis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Predicted Interactions

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Your Input:
	AEG58328.1	TIGRFAM: D-3-phosphoglycerate dehydrogenase; KEGG: drm:Dred_0014 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein. (526 aa)
	AEG58465.1	KEGG: drm:Dred_0097 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein. (404 aa)
	AEG58655.1	TIGRFAM: acetolactate synthase, small subunit; KEGG: drm:Dred_0282 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein. (170 aa)
	AEG58880.1	PFAM: malic protein NAD-binding; malic protein domain protein; amino acid-binding ACT domain protein; KEGG: drm:Dred_2955 malate dehydrogenase. (475 aa)
	AEG59017.1	KEGG: drm:Dred_2896 acetolactate synthase 3 regulatory subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein. (171 aa)
	AEG59028.1	PFAM: amino acid-binding ACT domain protein; KEGG: drm:Dred_2883 amino acid-binding ACT domain-containing protein. (143 aa)
	AEG60177.1	KEGG: drm:Dred_1940 aspartate kinase I; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (411 aa)
	AEG60504.1	TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor interaction domain-containing protein; PAS fold domain protein; amino acid-binding ACT domain protein; KEGG: dhd:Dhaf_1326 putative sigma54 specific transcriptional regulator; SMART: PAS domain containing protein; AAA ATPase. (538 aa)
	AEG60617.1	PFAM: amino acid-binding ACT domain protein; KEGG: drm:Dred_1671 hypothetical protein; Belongs to the UPF0237 family. (100 aa)
	pheA	KEGG: dau:Daud_1904 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein. (279 aa)
	AEG61040.1	KEGG: drm:Dred_1256 signal-transduction protein; PFAM: CBS domain containing protein; amino acid-binding ACT domain protein; SMART: CBS domain containing protein. (210 aa)
	AEG61045.1	TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; KEGG: drm:Dred_1252 L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: serine dehydratase beta chain; amino acid-binding ACT domain protein. (220 aa)
	AEG61140.1	KEGG: drm:Dred_1167 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (404 aa)
	AEG61142.1	KEGG: drm:Dred_1165 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. (430 aa)
	AEG61143.1	PFAM: amino acid-binding ACT domain protein; KEGG: drm:Dred_1164 hypothetical protein; Belongs to the UPF0735 family. (148 aa)
	AEG61476.1	RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (723 aa)
	AEG61564.1	TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor interaction domain-containing protein; PAS fold domain protein; KEGG: drm:Dred_0663 putative PAS/PAC sensor protein; SMART: AAA ATPase; PAS domain containing protein. (526 aa)

Your Current Organism:

Desulfotomaculum ruminis

NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AEG58328.1	AEG61142.1	Desru_0022	Desru_2928	TIGRFAM: D-3-phosphoglycerate dehydrogenase; KEGG: drm:Dred_0014 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein.	KEGG: drm:Dred_1165 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein.	0.495
AEG58465.1	AEG58655.1	Desru_0166	Desru_0358	KEGG: drm:Dred_0097 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein.	TIGRFAM: acetolactate synthase, small subunit; KEGG: drm:Dred_0282 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.	0.966
AEG58465.1	AEG59017.1	Desru_0166	Desru_0734	KEGG: drm:Dred_0097 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein.	KEGG: drm:Dred_2896 acetolactate synthase 3 regulatory subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.	0.966
AEG58465.1	AEG60177.1	Desru_0166	Desru_1918	KEGG: drm:Dred_0097 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein.	KEGG: drm:Dred_1940 aspartate kinase I; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family.	0.594
AEG58465.1	AEG61045.1	Desru_0166	Desru_2831	KEGG: drm:Dred_0097 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein.	TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; KEGG: drm:Dred_1252 L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: serine dehydratase beta chain; amino acid-binding ACT domain protein.	0.936
AEG58465.1	AEG61140.1	Desru_0166	Desru_2926	KEGG: drm:Dred_0097 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein.	KEGG: drm:Dred_1167 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family.	0.594
AEG58465.1	AEG61142.1	Desru_0166	Desru_2928	KEGG: drm:Dred_0097 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein.	KEGG: drm:Dred_1165 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein.	0.736
AEG58465.1	pheA	Desru_0166	Desru_2589	KEGG: drm:Dred_0097 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein.	KEGG: dau:Daud_1904 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein.	0.706
AEG58655.1	AEG58465.1	Desru_0358	Desru_0166	TIGRFAM: acetolactate synthase, small subunit; KEGG: drm:Dred_0282 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.	KEGG: drm:Dred_0097 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein.	0.966
AEG58655.1	AEG58880.1	Desru_0358	Desru_0595	TIGRFAM: acetolactate synthase, small subunit; KEGG: drm:Dred_0282 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.	PFAM: malic protein NAD-binding; malic protein domain protein; amino acid-binding ACT domain protein; KEGG: drm:Dred_2955 malate dehydrogenase.	0.824
AEG58655.1	AEG59017.1	Desru_0358	Desru_0734	TIGRFAM: acetolactate synthase, small subunit; KEGG: drm:Dred_0282 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.	KEGG: drm:Dred_2896 acetolactate synthase 3 regulatory subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.	0.905
AEG58655.1	AEG61142.1	Desru_0358	Desru_2928	TIGRFAM: acetolactate synthase, small subunit; KEGG: drm:Dred_0282 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.	KEGG: drm:Dred_1165 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein.	0.721
AEG58655.1	pheA	Desru_0358	Desru_2589	TIGRFAM: acetolactate synthase, small subunit; KEGG: drm:Dred_0282 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.	KEGG: dau:Daud_1904 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein.	0.596
AEG58880.1	AEG58655.1	Desru_0595	Desru_0358	PFAM: malic protein NAD-binding; malic protein domain protein; amino acid-binding ACT domain protein; KEGG: drm:Dred_2955 malate dehydrogenase.	TIGRFAM: acetolactate synthase, small subunit; KEGG: drm:Dred_0282 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.	0.824
AEG58880.1	AEG59017.1	Desru_0595	Desru_0734	PFAM: malic protein NAD-binding; malic protein domain protein; amino acid-binding ACT domain protein; KEGG: drm:Dred_2955 malate dehydrogenase.	KEGG: drm:Dred_2896 acetolactate synthase 3 regulatory subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.	0.824
AEG59017.1	AEG58465.1	Desru_0734	Desru_0166	KEGG: drm:Dred_2896 acetolactate synthase 3 regulatory subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.	KEGG: drm:Dred_0097 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein.	0.966
AEG59017.1	AEG58655.1	Desru_0734	Desru_0358	KEGG: drm:Dred_2896 acetolactate synthase 3 regulatory subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.	TIGRFAM: acetolactate synthase, small subunit; KEGG: drm:Dred_0282 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.	0.905
AEG59017.1	AEG58880.1	Desru_0734	Desru_0595	KEGG: drm:Dred_2896 acetolactate synthase 3 regulatory subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.	PFAM: malic protein NAD-binding; malic protein domain protein; amino acid-binding ACT domain protein; KEGG: drm:Dred_2955 malate dehydrogenase.	0.824
AEG59017.1	AEG61142.1	Desru_0734	Desru_2928	KEGG: drm:Dred_2896 acetolactate synthase 3 regulatory subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.	KEGG: drm:Dred_1165 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein.	0.721
AEG59017.1	pheA	Desru_0734	Desru_2589	KEGG: drm:Dred_2896 acetolactate synthase 3 regulatory subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.	KEGG: dau:Daud_1904 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein.	0.588

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