STRINGSTRING
argD argD AEG58327.1 AEG58327.1 AEG58639.1 AEG58639.1 AEG58682.1 AEG58682.1 AEG58838.1 AEG58838.1 AEG58854.1 AEG58854.1 AEG58874.1 AEG58874.1 AEG59188.1 AEG59188.1 AEG59493.1 AEG59493.1 AEG59508.1 AEG59508.1 hisC hisC hemL hemL AEG60059.1 AEG60059.1 AEG60089.1 AEG60089.1 AEG60092.1 AEG60092.1 AEG60207.1 AEG60207.1 AEG60567.1 AEG60567.1 dapL dapL AEG61169.1 AEG61169.1 iscS iscS gcvPB gcvPB gcvPA gcvPA glyA glyA glyA-2 glyA-2 AEG61929.1 AEG61929.1 rocD rocD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
argDTIGRFAM: acetylornithine and succinylornithine aminotransferase; KEGG: drm:Dred_0274 acetylornithine aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (399 aa)
AEG58327.1PFAM: aminotransferase class V; KEGG: drm:Dred_0013 aminotransferase, class V. (385 aa)
AEG58639.1KEGG: drm:Dred_0266 cysteine desulfurase family protein; TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase class V. (390 aa)
AEG58682.1Regulatory protein GntR HTH; KEGG: clj:CLJU_c08850 putative transcriptional regulator; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH. (444 aa)
AEG58838.1PFAM: aminotransferase class I and II; KEGG: drm:Dred_2905 GntR family transcriptional regulator. (392 aa)
AEG58854.1Regulatory protein GntR HTH; KEGG: drm:Dred_2906 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH. (505 aa)
AEG58874.1PFAM: aminotransferase class-III; KEGG: dvm:DvMF_0516 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (462 aa)
AEG59188.1KEGG: drm:Dred_2701 putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II. (362 aa)
AEG59493.1KEGG: npu:Npun_R0689 DegT/DnrJ/EryC1/StrS aminotransferase; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (386 aa)
AEG59508.1PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: drm:Dred_2412 DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (357 aa)
hisCKEGG: drm:Dred_2354 histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (361 aa)
hemLKEGG: drm:Dred_2156 glutamate-1-semialdehyde-2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III. (432 aa)
AEG60059.1Acetylornithine transaminase; KEGG: drm:Dred_2058 aminotransferase class-III; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (470 aa)
AEG60089.1PFAM: aminotransferase class I and II; KEGG: drt:Dret_1447 aminotransferase class I and II. (373 aa)
AEG60092.1TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: hmo:HM1_0096 O-acetylhomoserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (427 aa)
AEG60207.1PFAM: aminotransferase class I and II; KEGG: drm:Dred_1913 aminotransferase, class I and II. (388 aa)
AEG60567.1PFAM: aminotransferase class I and II; KEGG: drm:Dred_1696 aminotransferase, class I and II. (397 aa)
dapLLL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (392 aa)
AEG61169.1PFAM: aminotransferase class I and II; KEGG: drm:Dred_1148 aspartate aminotransferase. (394 aa)
iscSCysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (415 aa)
gcvPBGlycine cleavage system P-protein-like protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (484 aa)
gcvPAGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (446 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (408 aa)
glyA-2Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa)
AEG61929.1PFAM: aminotransferase class I and II; KEGG: drm:Dred_3192 aminotransferase, class I and II. (390 aa)
rocDOrnithine aminotransferase; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (396 aa)
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
Server load: low (14%) [HD]