STRINGSTRING
AEE95472.1 AEE95472.1 AEE95868.1 AEE95868.1 ackA ackA AEE96021.1 AEE96021.1 ackA-2 ackA-2 AEE96088.1 AEE96088.1 AEE96092.1 AEE96092.1 AEE96093.1 AEE96093.1 AEE96094.1 AEE96094.1 AEE96095.1 AEE96095.1 glyA glyA AEE96505.1 AEE96505.1 AEE96570.1 AEE96570.1 eno eno gpmI gpmI AEE96854.1 AEE96854.1 ackA-3 ackA-3 AEE96881.1 AEE96881.1 AEE96889.1 AEE96889.1 pfkA pfkA AEE97183.1 AEE97183.1 AEE97184.1 AEE97184.1 AEE97185.1 AEE97185.1 AEE97186.1 AEE97186.1 AEE97210.1 AEE97210.1 pfp pfp comB comB AEE97808.1 AEE97808.1 AEE97843.1 AEE97843.1 AEE97897.1 AEE97897.1 AEE98088.1 AEE98088.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AEE95472.1COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771: IPR011289; KEGG: chy:CHY_0128 fructose-1,6-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; class II aldolase, tagatose bisphosphate family; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist. (283 aa)
AEE95868.1COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006236: IPR006139: IPR006140: IPR002912; KEGG: tpd:Teth39_0145 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; PRIAM: Phosphoglycerate dehydrogenase; SPTR: D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyaci [...] (531 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa)
AEE96021.1COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: pam:PANA_2380 FbaA; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Putative uncharacterized protein; TIGRFAM: ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases. (354 aa)
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
AEE96088.1FAD dependent oxidoreductase; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR006076; KEGG: dat:HRM2_30780 putative fusion protein, heterodisulfide reductase (HdrA) / ferredoxin (iron-sulfur-binding protein); PFAM: FAD dependent oxidoreductase; SPTR: Putative fusion protein, heterodisulfide reductase (HdrA) / ferredoxin (Iron-sulfur-binding protein); PFAM: Pyridine nucleotide-disulphide oxidoreductase. (348 aa)
AEE96092.1Hypothetical protein; COGs: COG1150 Heterodisulfide reductase subunit C; InterPro IPR017896: IPR017900; KEGG: dak:DaAHT2_1634 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding; TIGRFAM: CoB--CoM heterodisulfide reductase, subunit C. (148 aa)
AEE96093.1Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR017896: IPR013027: IPR002218: IPR001327: IPR 003953: IPR017900; KEGG: dae:Dtox_1277 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; glucose-inhibited division protein A; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: FAD binding domain; Glucose inhibited division p [...] (1009 aa)
AEE96094.1COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: dae:Dtox_1278 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; SPTR: Methyl-viologen-reducing hydrogenase delta subunit; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit. (146 aa)
AEE96095.1InterPro IPR017896: IPR017900; KEGG: dae:Dtox_1279 coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; SPTR: Coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein. (284 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
AEE96505.1COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139: IPR006140; KEGG: tit:Thit_1574 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; PRIAM: Phosphoglycerate dehydrogenase; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (320 aa)
AEE96570.1COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: ate:Athe_2390 ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Ketose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases. (280 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
gpmIPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (513 aa)
AEE96854.1COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771: IPR011289; KEGG: chy:CHY_0128 fructose-1,6-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; class II aldolase, tagatose bisphosphate family; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist. (287 aa)
ackA-3Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (401 aa)
AEE96881.1COGs: COG0280 Phosphotransacetylase; InterPro IPR002505: IPR004614: IPR012147; KEGG: tte:TTE1482 phosphotransacetylase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: Phosphate acetyltransferase; SPTR: Phosphotransacetylase; TIGRFAM: phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase. (328 aa)
AEE96889.14Fe-4S ferredoxin iron-sulfur binding domain-containing protein; COGs: COG1142 Fe-S-cluster-containing hydrogenase components 2; InterPro IPR017900: IPR017896; KEGG: tex:Teth514_0560 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain. (146 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (325 aa)
AEE97183.1Thiamine pyrophosphate TPP-binding domain-containing protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: cth:Cthe_2393 thiamine pyrophosphate enzyme-like TPP-binding; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Thiamine pyrophosphate enzyme-like TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. (311 aa)
AEE97184.1Pyruvate ferredoxin oxidoreductase, alpha subunit; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: csc:Csac_1460 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: Pyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: domain. (393 aa)
AEE97185.1COGs: COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase delta subunit; InterPro IPR011898: IPR017896: IPR017900; KEGG: cth:Cthe_2391 pyruvate ferredoxin oxidoreductase, delta subunit; SPTR: Pyruvate synthase subunit porD; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family. (103 aa)
AEE97186.1Pyruvate ferredoxin oxidoreductase, gamma subunit; COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR011894: IPR019752; KEGG: cth:Cthe_2390 pyruvate ferredoxin oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: Pyruvate ferredoxin oxidoreductase, gamma subunit; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family. (192 aa)
AEE97210.1COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: adg:Adeg_0056 fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: 5-dehydro-2-deoxyphosphogluconate aldolase; SPTR: Fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases. (312 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (390 aa)
comB2-phosphosulfolactate phosphatase; COGs: COG2045 Phosphosulfolactate phosphohydrolase; InterPro IPR005238; KEGG: tpd:Teth39_0568 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulfolactate phosphatase; SPTR: 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulpholactate phosphatase; TIGRFAM: 2-phosphosulfolactate phosphatase; Belongs to the ComB family. (242 aa)
AEE97808.1Hypothetical protein; KEGG: mac:MA0146 methylcobalamin:coenzyme M methyltransferase; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D); Belongs to the uroporphyrinogen decarboxylase family. (347 aa)
AEE97843.1COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: tit:Thit_1576 ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Ketose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases. (282 aa)
AEE97897.1COGs: COG5598 Trimethylamine:corrinoid methyltransferase; InterPro IPR010426; KEGG: dat:HRM2_44210 MttB10; PFAM: trimethylamine methyltransferase; SPTR: MttB10; PFAM: Trimethylamine methyltransferase (MTTB). (466 aa)
AEE98088.1Hypothetical protein; COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: mae:Maeo_0598 uroporphyrinogen decarboxylase; SPTR: Uroporphyrinogen decarboxylase (URO-D); PFAM: Uroporphyrinogen decarboxylase (URO-D); Belongs to the uroporphyrinogen decarboxylase family. (354 aa)
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.