STRINGSTRING
EGW19983.1 EGW19983.1 EGW23278.1 EGW23278.1 thiL thiL dxs dxs adk adk EGW21320.1 EGW21320.1 EGW21269.1 EGW21269.1 EGW21268.1 EGW21268.1 EGW21147.1 EGW21147.1 thiE thiE rsgA rsgA EGW20259.1 EGW20259.1 thiG thiG EGW19898.1 EGW19898.1 EGW19880.1 EGW19880.1 EGW23699.1 EGW23699.1 thiC thiC EGW23613.1 EGW23613.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EGW19983.1KEGG: mmb:Mmol_0260 alkaline phosphatase; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; Belongs to the alkaline phosphatase family. (546 aa)
EGW23278.1KEGG: mca:MCA2506 Rrf2 family protein; TIGRFAM: Transcriptional regulator, Rrf2; PFAM: Transcriptional regulator, Rrf2. (151 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (311 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (620 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (212 aa)
EGW21320.1KEGG: nhl:Nhal_3853 mutator MutT protein; TIGRFAM: Mutator MutT protein; PFAM: Thiamine monophosphate synthase; NUDIX hydrolase domain. (307 aa)
EGW21269.1Transcriptional regulator, BadM/Rrf2 family; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. (157 aa)
EGW21268.1KEGG: mca:MCA2884 cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase. (368 aa)
EGW21147.1KEGG: tgr:Tgr7_2419 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. (262 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (206 aa)
rsgARibosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (295 aa)
EGW20259.1Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. (402 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (325 aa)
EGW19898.1PFAM: FAD dependent oxidoreductase; KEGG: sli:Slin_3588 FAD dependent oxidoreductase. (353 aa)
EGW19880.1Transcriptional regulator, BadM/Rrf2 family; KEGG: mca:MCA0993 Rrf2 family protein; TIGRFAM: SUF system FeS cluster assembly, Rtf2-type regulator; Transcriptional regulator, Rrf2; PFAM: Transcriptional regulator, Rrf2. (149 aa)
EGW23699.1KEGG: sfu:Sfum_3969 hypothetical protein. (212 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (626 aa)
EGW23613.1TIGRFAM: Glycine oxidase ThiO; KEGG: alv:Alvin_1597 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase. (366 aa)
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.