STRINGSTRING
metK metK AEM78927.1 AEM78927.1 AEM78941.1 AEM78941.1 AEM79071.1 AEM79071.1 AEM79158.1 AEM79158.1 AEM79159.1 AEM79159.1 metXA metXA AEM79415.1 AEM79415.1 AEM79416.1 AEM79416.1 thrB thrB AEM79931.1 AEM79931.1 AEM79932.1 AEM79932.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
metKS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (395 aa)
AEM78927.1PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; KEGG: tmt:Tmath_1414 Cys/Met metabolism pyridoxal-phosphate-dependent protein. (393 aa)
AEM78941.1PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; KEGG: tbo:Thebr_0909 Cys/Met metabolism pyridoxal-phosphate-dependent protein. (396 aa)
AEM79071.1KEGG: thx:Thet_0868 putative GAF sensor protein; PFAM: GAF; SMART: GAF. (154 aa)
AEM79158.1PFAM: Homocysteine S-methyltransferase; Dihydropteroate synthase, DHPS; Methionine synthase, cobalamin (vitamin B12)-binding module, cap; Cobalamin (vitamin B12)-binding; KEGG: tbo:Thebr_0717 homocysteine S-methyltransferase. (807 aa)
AEM79159.1PFAM: Methylenetetrahydrofolate reductase; KEGG: thx:Thet_1699 methylenetetrahydrofolate reductase. (303 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (366 aa)
AEM79415.1KEGG: thx:Thet_1939 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme. (427 aa)
AEM79416.1PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; KEGG: tmt:Tmath_1812 homoserine dehydrogenase. (427 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (308 aa)
AEM79931.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (351 aa)
AEM79932.1PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; KEGG: tbo:Thebr_0146 homoserine dehydrogenase. (418 aa)
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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