85 items (Penicillium decumbens) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1V6PIM8	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (111 aa)
	A0A1V6PIU4	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (143 aa)
	A0A1V6PJT8	Peripheral subunit-binding (PSBD) domain-containing protein. (285 aa)
	A0A1V6PJW2	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (488 aa)
	A0A1V6PKT4	Uncharacterized protein. (716 aa)
	A0A1V6PL34	Protein kinase domain-containing protein. (823 aa)
	A0A1V6PL50	Aldo_ket_red domain-containing protein. (297 aa)
	A0A1V6PLA7	Aldo_ket_red domain-containing protein. (480 aa)
	A0A1V6PLK5	Uncharacterized protein. (176 aa)
	A0A1V6PLM4	Uncharacterized protein. (451 aa)
	A0A1V6PM24	DUF2235 domain-containing protein. (670 aa)
	A0A1V6PMA4	Glycosidase; Belongs to the glycosyl hydrolase 16 family. (415 aa)
	A0A1V6PMM2	RNA_pol_L_2 domain-containing protein. (192 aa)
	A0A1V6PMN1	Uncharacterized protein. (396 aa)
	A0A1V6PMU7	Uncharacterized protein. (376 aa)
	A0A1V6PNA0	Uncharacterized protein. (281 aa)
	A0A1V6PP08	Uncharacterized protein. (261 aa)
	A0A1V6PP31	Uncharacterized protein. (235 aa)
	A0A1V6PPC3	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1726 aa)
	A0A1V6P7F0	Uncharacterized protein. (281 aa)
	A0A1V6P7F7	Uncharacterized protein. (405 aa)
	A0A1V6P7H0	RPOLD domain-containing protein. (331 aa)
	A0A1V6P7L9	GATA-type domain-containing protein. (300 aa)
	A0A1V6P7N0	ADH_zinc_N domain-containing protein. (122 aa)
	A0A1V6P7N9	Uncharacterized protein. (530 aa)
	A0A1V6P7Q4	Aldo_ket_red domain-containing protein. (319 aa)
	A0A1V6P7Z0	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (455 aa)
	A0A1V6P8A2	Uncharacterized protein. (419 aa)
	A0A1V6P8J1	Uncharacterized protein. (158 aa)
	A0A1V6P8K1	Uncharacterized protein; Belongs to the cyclin family. (387 aa)
	A0A1V6P8P2	Uncharacterized protein. (281 aa)
	A0A1V6P8T8	Aldo_ket_red domain-containing protein. (315 aa)
	A0A1V6P9A8	Uncharacterized protein. (271 aa)
	A0A1V6PBX1	Uncharacterized protein. (257 aa)
	A0A1V6P9C0	AB hydrolase-1 domain-containing protein. (525 aa)
	A0A1V6PBU2	PKS_ER domain-containing protein. (389 aa)
	A0A1V6PAU5	Aldo_ket_red domain-containing protein. (303 aa)
	calI	Oxidoreductase calI; Oxidoreductase; part of the gene cluster that mediates the biosynthesis of calbistrin A and related compounds. Calbistrin A is a secondary metabolite with an interesting structure that was recently found to have bioactivity against leukemia cells. It consists of two polyketides linked by an ester bond: a bicyclic decalin containing polyketide and a linear 12 carbon dioic acid structure. The polyketide synthase calA is probably responsible for forming the decalin moiety. Because calA lacks a designated enoylreductase (ER) domain, the required activity is provided by [...] (346 aa)
	A0A1V6PAD5	Uncharacterized protein. (815 aa)
	A0A1V6PAD0	Histone H2B; Belongs to the histone H2B family. (140 aa)
	A0A1V6PA88	Uncharacterized protein. (244 aa)
	A0A1V6PA34	Uncharacterized protein. (222 aa)
	A0A1V6P9Y1	Aldedh domain-containing protein. (515 aa)
	A0A1V6P9X7	Uncharacterized protein. (521 aa)
	A0A1V6P9U3	Uncharacterized protein. (712 aa)
	A0A1V6P9K0	Uncharacterized protein. (320 aa)
	A0A1V6P742	HATPase_c domain-containing protein. (700 aa)
	A0A1V6P6L5	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1255 aa)
	A0A1V6P6F7	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (502 aa)
	A0A1V6P684	Uncharacterized protein. (77 aa)
	A0A1V6P5Z6	Aldo_ket_red domain-containing protein. (325 aa)
	A0A1V6P221	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (524 aa)
	A0A1V6P1E8	Ig-like domain-containing protein. (772 aa)
	A0A1V6P158	Uncharacterized protein. (345 aa)
	A0A1V6P0P6	Uncharacterized protein. (344 aa)
	A0A1V6P0P2	Protein kinase domain-containing protein. (519 aa)
	A0A1V6P0K3	Fork-head domain-containing protein. (626 aa)
	A0A1V6P0A7	Aldo_ket_red domain-containing protein. (294 aa)
	A0A1V6NZH9	Uncharacterized protein. (376 aa)
	A0A1V6NVK4	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (374 aa)
	A0A1V6NS00	Uncharacterized protein. (309 aa)
	A0A1V6NRS7	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (512 aa)
	A0A1V6NRF7	TFIIS-type domain-containing protein; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (195 aa)
	A0A1V6NR33	WD_REPEATS_REGION domain-containing protein. (831 aa)
	A0A1V6NQX1	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (697 aa)
	A0A1V6PDB8	Uncharacterized protein. (424 aa)
	A0A1V6PDQ7	Uncharacterized protein. (323 aa)
	A0A1V6PDT0	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1085 aa)
	A0A1V6PDU1	Uncharacterized protein. (290 aa)
	A0A1V6PDV5	Protein kinase domain-containing protein. (225 aa)
	A0A1V6PEU2	Aldo_ket_red domain-containing protein. (313 aa)
	A0A1V6PEZ1	Aldedh domain-containing protein. (432 aa)
	A0A1V6PF79	Aldo_ket_red domain-containing protein. (334 aa)
	A0A1V6PFK0	Protein-serine/threonine kinase. (499 aa)
	A0A1V6PFV0	Uncharacterized protein. (316 aa)
	A0A1V6PFV9	Uncharacterized protein; Belongs to the cyclin family. (449 aa)
	A0A1V6PG43	Uncharacterized protein. (462 aa)
	A0A1V6PG46	Uncharacterized protein. (262 aa)
	A0A1V6PG95	Uncharacterized protein. (95 aa)
	A0A1V6PGT3	GATA-type domain-containing protein. (866 aa)
	cprA	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (695 aa)
	A0A1V6PH53	Uncharacterized protein. (321 aa)
	A0A1V6PHJ8	Uncharacterized protein. (268 aa)
	A0A1V6PIA4	Uncharacterized protein. (267 aa)
	A0A1V6PIH9	Uncharacterized protein. (475 aa)

Your Current Organism:

Penicillium decumbens

NCBI taxonomy Id: 69771
Other names: CBS 230.81, FRR 741, NRRL 741, P. decumbens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1V6NQX1	A0A1V6NRF7	A0A1V6NQX1	A0A1V6NRF7	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	TFIIS-type domain-containing protein; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.997
A0A1V6NQX1	A0A1V6P684	A0A1V6NQX1	A0A1V6P684	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Uncharacterized protein.	0.973
A0A1V6NQX1	A0A1V6P6L5	A0A1V6NQX1	A0A1V6P6L5	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.996
A0A1V6NQX1	A0A1V6P7H0	A0A1V6NQX1	A0A1V6P7H0	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	RPOLD domain-containing protein.	0.994
A0A1V6NQX1	A0A1V6P8J1	A0A1V6NQX1	A0A1V6P8J1	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Uncharacterized protein.	0.977
A0A1V6NQX1	A0A1V6P8K1	A0A1V6NQX1	A0A1V6P8K1	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Uncharacterized protein; Belongs to the cyclin family.	0.639
A0A1V6NQX1	A0A1V6P9U3	A0A1V6NQX1	A0A1V6P9U3	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Uncharacterized protein.	0.668
A0A1V6NQX1	A0A1V6P9X7	A0A1V6NQX1	A0A1V6P9X7	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Uncharacterized protein.	0.946
A0A1V6NQX1	A0A1V6PA88	A0A1V6NQX1	A0A1V6PA88	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Uncharacterized protein.	0.967
A0A1V6NQX1	A0A1V6PAD0	A0A1V6NQX1	A0A1V6PAD0	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Histone H2B; Belongs to the histone H2B family.	0.556
A0A1V6NQX1	A0A1V6PAD5	A0A1V6NQX1	A0A1V6PAD5	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Uncharacterized protein.	0.999
A0A1V6NQX1	A0A1V6PFV9	A0A1V6NQX1	A0A1V6PFV9	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Uncharacterized protein; Belongs to the cyclin family.	0.639
A0A1V6NQX1	A0A1V6PG46	A0A1V6NQX1	A0A1V6PG46	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Uncharacterized protein.	0.985
A0A1V6NQX1	A0A1V6PIM8	A0A1V6NQX1	A0A1V6PIM8	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.982
A0A1V6NQX1	A0A1V6PIU4	A0A1V6NQX1	A0A1V6PIU4	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.970
A0A1V6NQX1	A0A1V6PMM2	A0A1V6NQX1	A0A1V6PMM2	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	RNA_pol_L_2 domain-containing protein.	0.976
A0A1V6NQX1	A0A1V6PMU7	A0A1V6NQX1	A0A1V6PMU7	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Uncharacterized protein.	0.977
A0A1V6NQX1	A0A1V6PP31	A0A1V6NQX1	A0A1V6PP31	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Uncharacterized protein.	0.987
A0A1V6NQX1	A0A1V6PPC3	A0A1V6NQX1	A0A1V6PPC3	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.970
A0A1V6NRF7	A0A1V6NQX1	A0A1V6NRF7	A0A1V6NQX1	TFIIS-type domain-containing protein; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.997