STRINGSTRING
G7K_0070-t2 G7K_0070-t2 G7K_0125-t1 G7K_0125-t1 G7K_0158-t1 G7K_0158-t1 G7K_0016-t1 G7K_0016-t1 G7K_0057-t1 G7K_0057-t1 G7K_6628-t1 G7K_6628-t1 G7K_6664-t1 G7K_6664-t1 G7K_6622-t1 G7K_6622-t1 G7K_6647-t1 G7K_6647-t1 G7K_6548-t1 G7K_6548-t1 G7K_6606-t1 G7K_6606-t1 G7K_6058-t1 G7K_6058-t1 G7K_6470-t1 G7K_6470-t1 G7K_6412-t1 G7K_6412-t1 G7K_5980-t2 G7K_5980-t2 G7K_6271-t1 G7K_6271-t1 G7K_6220-t1 G7K_6220-t1 G7K_5793-t1 G7K_5793-t1 G7K_6145-t1 G7K_6145-t1 G7K_5980-t3 G7K_5980-t3 G7K_5619-t1 G7K_5619-t1 G7K_5864-t1 G7K_5864-t1 G7K_6020-t1 G7K_6020-t1 G7K_5980-t1 G7K_5980-t1 G7K_5857-t1 G7K_5857-t1 G7K_5837-t1 G7K_5837-t1 G7K_5810-t1 G7K_5810-t1 G7K_5752-t1 G7K_5752-t1 G7K_5672-t1 G7K_5672-t1 G7K_5737-t1 G7K_5737-t1 G7K_5732-t1 G7K_5732-t1 G7K_5653-t1 G7K_5653-t1 G7K_5550-t1 G7K_5550-t1 G7K_5049-t1 G7K_5049-t1 G7K_5441-t1 G7K_5441-t1 G7K_5436-t1 G7K_5436-t1 G7K_5394-t1 G7K_5394-t1 G7K_5340-t1 G7K_5340-t1 G7K_4896-t1 G7K_4896-t1 G7K_5318-t1 G7K_5318-t1 G7K_5260-t1 G7K_5260-t1 G7K_5228-t1 G7K_5228-t1 G7K_4734-t1 G7K_4734-t1 G7K_5007-t1 G7K_5007-t1 G7K_4987-t1 G7K_4987-t1 G7K_4940-t1 G7K_4940-t1 G7K_4752-t1 G7K_4752-t1 G7K_4791-t1 G7K_4791-t1 G7K_4753-t1 G7K_4753-t1 G7K_4682-t1 G7K_4682-t1 G7K_4549-t1 G7K_4549-t1 NTH1 NTH1 G7K_4553-t1 G7K_4553-t1 G7K_4466-t1 G7K_4466-t1 G7K_4481-t1 G7K_4481-t1 G7K_4012-t1 G7K_4012-t1 G7K_4300-t1 G7K_4300-t1 G7K_4221-t1 G7K_4221-t1 G7K_3863-t1 G7K_3863-t1 G7K_4184-t1 G7K_4184-t1 PIF1 PIF1 G7K_3985-t1 G7K_3985-t1 G7K_3966-t1 G7K_3966-t1 G7K_3847-t1 G7K_3847-t1 G7K_3895-t1 G7K_3895-t1 G7K_3496-t1 G7K_3496-t1 G7K_3807-t1 G7K_3807-t1 G7K_3376-t2 G7K_3376-t2 G7K_3773-t1 G7K_3773-t1 G7K_3556-t1 G7K_3556-t1 VMA21 VMA21 G7K_3641-t1 G7K_3641-t1 G7K_3472-t1 G7K_3472-t1 G7K_3390-t1 G7K_3390-t1 G7K_3509-t1 G7K_3509-t1 G7K_3349-t1 G7K_3349-t1 G7K_3465-t1 G7K_3465-t1 G7K_3436-t1 G7K_3436-t1 G7K_3376-t1 G7K_3376-t1 G7K_3352-t1 G7K_3352-t1 SLX1 SLX1 G7K_3030-t1 G7K_3030-t1 G7K_2753-t1 G7K_2753-t1 G7K_3099-t1 G7K_3099-t1 G7K_3130-t1 G7K_3130-t1 G7K_3085-t1 G7K_3085-t1 G7K_3072-t1 G7K_3072-t1 G7K_2930-t1 G7K_2930-t1 G7K_2543-t1 G7K_2543-t1 G7K_2873-t1 G7K_2873-t1 G7K_2704-t1 G7K_2704-t1 G7K_2684-t1 G7K_2684-t1 G7K_2375-t1 G7K_2375-t1 G7K_2365-t1 G7K_2365-t1 FEN1 FEN1 G7K_2594-t1 G7K_2594-t1 G7K_2696-t1 G7K_2696-t1 G7K_2591-t1 G7K_2591-t1 G7K_2158-t1 G7K_2158-t1 G7K_2443-t1 G7K_2443-t1 G7K_2036-t1 G7K_2036-t1 G7K_2325-t1 G7K_2325-t1 G7K_2298-t1 G7K_2298-t1 G7K_1787-t1 G7K_1787-t1 G7K_2147-t1 G7K_2147-t1 G7K_2158-t2 G7K_2158-t2 G7K_2110-t1 G7K_2110-t1 G7K_2009-t1 G7K_2009-t1 G7K_2108-t1 G7K_2108-t1 G7K_1972-t1 G7K_1972-t1 G7K_1538-t1 G7K_1538-t1 G7K_1302-t1 G7K_1302-t1 G7K_1710-t1 G7K_1710-t1 G7K_1267-t1 G7K_1267-t1 G7K_1641-t1 G7K_1641-t1 G7K_1491-t1 G7K_1491-t1 G7K_1083-t1 G7K_1083-t1 G7K_1488-t1 G7K_1488-t1 G7K_1479-t1 G7K_1479-t1 G7K_1043-t1 G7K_1043-t1 G7K_1433-t1 G7K_1433-t1 G7K_1454-t1 G7K_1454-t1 G7K_1467-t1 G7K_1467-t1 G7K_1249-t1 G7K_1249-t1 G7K_1291-t1 G7K_1291-t1 MCM7 MCM7 G7K_1260-t1 G7K_1260-t1 G7K_1012-t1 G7K_1012-t1 G7K_1075-t1 G7K_1075-t1 G7K_0990-t1 G7K_0990-t1 G7K_1040-t1 G7K_1040-t1 G7K_0853-t1 G7K_0853-t1 G7K_0485-t1 G7K_0485-t1 G7K_0906-t1 G7K_0906-t1 G7K_0687-t1 G7K_0687-t1 G7K_0298-t1 G7K_0298-t1 G7K_0494-t1 G7K_0494-t1 G7K_0070-t1 G7K_0070-t1 G7K_0289-t1 G7K_0289-t1 G7K_0251-t1 G7K_0251-t1 UNG1 UNG1 G7K_0061-t1 G7K_0061-t1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G7K_0070-t2DNA ligase. (969 aa)
G7K_0125-t1Uncharacterized protein. (1112 aa)
G7K_0158-t1Uncharacterized protein. (919 aa)
G7K_0016-t1zf-C2HE domain-containing protein. (253 aa)
G7K_0057-t1DNA polymerase. (1257 aa)
G7K_6628-t1Uncharacterized protein. (1268 aa)
G7K_6664-t1DRMBL domain-containing protein. (787 aa)
G7K_6622-t1Uncharacterized protein. (2153 aa)
G7K_6647-t1DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). (921 aa)
G7K_6548-t1Uncharacterized protein. (1010 aa)
G7K_6606-t1Helicase ATP-binding domain-containing protein. (841 aa)
G7K_6058-t1Uncharacterized protein. (459 aa)
G7K_6470-t1Uncharacterized protein. (1667 aa)
G7K_6412-t1DNA helicase; Belongs to the MCM family. (928 aa)
G7K_5980-t2DNA_MISMATCH_REPAIR_2 domain-containing protein. (1334 aa)
G7K_6271-t1ENDO3c domain-containing protein. (573 aa)
G7K_6220-t1Uncharacterized protein. (1011 aa)
G7K_5793-t1Uncharacterized protein. (732 aa)
G7K_6145-t1Uncharacterized protein. (245 aa)
G7K_5980-t3DNA_MISMATCH_REPAIR_2 domain-containing protein. (665 aa)
G7K_5619-t1Uncharacterized protein. (2524 aa)
G7K_5864-t1HD_domain domain-containing protein. (276 aa)
G7K_6020-t1AAA domain-containing protein. (378 aa)
G7K_5980-t1MUTSd domain-containing protein. (691 aa)
G7K_5857-t1Uncharacterized protein. (196 aa)
G7K_5837-t1RT_RNaseH_2 domain-containing protein. (216 aa)
G7K_5810-t1Uncharacterized protein. (908 aa)
G7K_5752-t1Structural maintenance of chromosomes protein. (1324 aa)
G7K_5672-t1Ku domain-containing protein. (626 aa)
G7K_5737-t1ERCC4 domain-containing protein. (626 aa)
G7K_5732-t1MFS domain-containing protein; Belongs to the MRE11/RAD32 family. (1274 aa)
G7K_5653-t1Zn(2)-C6 fungal-type domain-containing protein. (822 aa)
G7K_5550-t1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (2064 aa)
G7K_5049-t1Structural maintenance of chromosomes protein. (1199 aa)
G7K_5441-t1AP_endonuc_2 domain-containing protein. (465 aa)
G7K_5436-t1Uncharacterized protein. (1267 aa)
G7K_5394-t1Uncharacterized protein. (1009 aa)
G7K_5340-t1AAA domain-containing protein. (457 aa)
G7K_4896-t1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (868 aa)
G7K_5318-t1Uncharacterized protein. (888 aa)
G7K_5260-t1DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (349 aa)
G7K_5228-t1FPG_CAT domain-containing protein. (544 aa)
G7K_4734-t1Uncharacterized protein. (1421 aa)
G7K_5007-t1Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (487 aa)
G7K_4987-t1Endonuclease. (330 aa)
G7K_4940-t1Structural maintenance of chromosomes protein. (1429 aa)
G7K_4752-t1Uncharacterized protein. (637 aa)
G7K_4791-t1Uncharacterized protein. (489 aa)
G7K_4753-t1Uncharacterized protein. (996 aa)
G7K_4682-t1Uncharacterized protein. (850 aa)
G7K_4549-t1AAA domain-containing protein. (665 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (452 aa)
G7K_4553-t1Uncharacterized protein. (1068 aa)
G7K_4466-t1AAA domain-containing protein. (348 aa)
G7K_4481-t1UmuC domain-containing protein. (598 aa)
G7K_4012-t1Rad51 domain-containing protein. (317 aa)
G7K_4300-t1Uncharacterized protein. (929 aa)
G7K_4221-t1Uncharacterized protein. (1548 aa)
G7K_3863-t1Uncharacterized protein. (1458 aa)
G7K_4184-t1POLAc domain-containing protein. (1175 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (951 aa)
G7K_3985-t1Uncharacterized protein. (1609 aa)
G7K_3966-t1Uncharacterized protein. (1052 aa)
G7K_3847-t1Uncharacterized protein. (1534 aa)
G7K_3895-t1Uncharacterized protein. (1931 aa)
G7K_3496-t1DNA_mis_repair domain-containing protein. (686 aa)
G7K_3807-t1DNA polymerase. (1132 aa)
G7K_3376-t2DNA helicase; Belongs to the MCM family. (1830 aa)
G7K_3773-t1UDG domain-containing protein. (429 aa)
G7K_3556-t1Uncharacterized protein. (1482 aa)
VMA21Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum; Belongs to the VMA21 family. (1741 aa)
G7K_3641-t1HORMA domain-containing protein. (243 aa)
G7K_3472-t1Cytosine-specific methyltransferase. (1405 aa)
G7K_3390-t1DNA_LIGASE_A3 domain-containing protein. (924 aa)
G7K_3509-t1BRCT domain-containing protein. (883 aa)
G7K_3349-t1Uncharacterized protein. (870 aa)
G7K_3465-t1UmuC domain-containing protein. (680 aa)
G7K_3436-t1DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1246 aa)
G7K_3376-t1DNA helicase; Belongs to the MCM family. (1810 aa)
G7K_3352-t1TP6A_N domain-containing protein. (437 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (560 aa)
G7K_3030-t1Uncharacterized protein; Belongs to the RecA family. (339 aa)
G7K_2753-t1DNA ligase. (905 aa)
G7K_3099-t1Uncharacterized protein. (1286 aa)
G7K_3130-t1Uncharacterized protein. (249 aa)
G7K_3085-t1Uncharacterized protein. (1550 aa)
G7K_3072-t1Uncharacterized protein. (564 aa)
G7K_2930-t1DNA ligase. (813 aa)
G7K_2543-t1VWFA domain-containing protein. (760 aa)
G7K_2873-t1Uncharacterized protein. (2220 aa)
G7K_2704-t1Uncharacterized protein. (323 aa)
G7K_2684-t1DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (407 aa)
G7K_2375-t1Uncharacterized protein. (645 aa)
G7K_2365-t1SMC_N domain-containing protein. (1228 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (1294 aa)
G7K_2594-t1Uncharacterized protein. (1965 aa)
G7K_2696-t1Ydc2-catalyt domain-containing protein. (379 aa)
G7K_2591-t1DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (645 aa)
G7K_2158-t1Replication factor C subunit 1. (1025 aa)
G7K_2443-t1Uncharacterized protein. (455 aa)
G7K_2036-t1ERCC4 domain-containing protein. (611 aa)
G7K_2325-t1Uncharacterized protein. (824 aa)
G7K_2298-t1Helicase ATP-binding domain-containing protein. (1337 aa)
G7K_1787-t1Uncharacterized protein. (1406 aa)
G7K_2147-t1AAA domain-containing protein. (358 aa)
G7K_2158-t2Replication factor C subunit 1. (1029 aa)
G7K_2110-t1Uncharacterized protein. (1618 aa)
G7K_2009-t1SMC_N domain-containing protein. (1131 aa)
G7K_2108-t1ENDO3c domain-containing protein. (421 aa)
G7K_1972-t1ERCC4 domain-containing protein. (978 aa)
G7K_1538-t1Structural maintenance of chromosomes protein. (1176 aa)
G7K_1302-t1DNA_MISMATCH_REPAIR_2 domain-containing protein. (873 aa)
G7K_1710-t1Uncharacterized protein. (1242 aa)
G7K_1267-t1Uncharacterized protein. (264 aa)
G7K_1641-t1DNA helicase; Belongs to the MCM family. (834 aa)
G7K_1491-t1RECA_2 domain-containing protein. (530 aa)
G7K_1083-t1DNA helicase; Belongs to the MCM family. (1614 aa)
G7K_1488-t1DNA_mis_repair domain-containing protein. (897 aa)
G7K_1479-t1Uncharacterized protein. (713 aa)
G7K_1043-t1Uncharacterized protein. (499 aa)
G7K_1433-t1Uncharacterized protein. (766 aa)
G7K_1454-t1Reverse transcriptase domain-containing protein. (773 aa)
G7K_1467-t1Uncharacterized protein. (1173 aa)
G7K_1249-t1UvrD_C_2 domain-containing protein. (965 aa)
G7K_1291-t1Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1108 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (1043 aa)
G7K_1260-t1DNA_MISMATCH_REPAIR_2 domain-containing protein. (1078 aa)
G7K_1012-t1Uncharacterized protein. (587 aa)
G7K_1075-t1DNA polymerase. (1610 aa)
G7K_0990-t1Uncharacterized protein. (997 aa)
G7K_1040-t1AAA_23 domain-containing protein. (1309 aa)
G7K_0853-t1Uncharacterized protein. (379 aa)
G7K_0485-t1RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (464 aa)
G7K_0906-t1Uncharacterized protein. (1620 aa)
G7K_0687-t1DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2222 aa)
G7K_0298-t1Uncharacterized protein. (1374 aa)
G7K_0494-t1POLIIIAc domain-containing protein. (456 aa)
G7K_0070-t1DNA ligase. (963 aa)
G7K_0289-t1DNA helicase; Belongs to the MCM family. (873 aa)
G7K_0251-t1Uncharacterized protein. (892 aa)
UNG1Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (415 aa)
G7K_0061-t1RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (463 aa)
Your Current Organism:
Saitoella complicata
NCBI taxonomy Id: 698492
Other names: S. complicata NRRL Y-17804, Saitoella complicata CBS 7301, Saitoella complicata CCRC 22490, Saitoella complicata IAM 12963, Saitoella complicata JCM 7358, Saitoella complicata NBRC 10748, Saitoella complicata NRRL Y-17804
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