48 items (Saitoella complicata) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	G7K_0057-t1	DNA polymerase. (1257 aa)
	G7K_0194-t1	Uncharacterized protein. (469 aa)
	G7K_0289-t1	DNA helicase; Belongs to the MCM family. (873 aa)
	G7K_0491-t1	Histone H2A; Belongs to the histone H2A family. (252 aa)
	G7K_0533-t1	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (200 aa)
	G7K_0499-t1	CBFD_NFYB_HMF domain-containing protein. (76 aa)
	G7K_0504-t1	Uncharacterized protein. (522 aa)
	G7K_1075-t1	DNA polymerase. (1610 aa)
	G7K_1051-t1	RPA_C domain-containing protein. (283 aa)
	G7K_1157-t1	NmrA domain-containing protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (805 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (1043 aa)
	G7K_1043-t1	Uncharacterized protein. (499 aa)
	G7K_1675-t1	Uncharacterized protein. (383 aa)
	G7K_2147-t1	AAA domain-containing protein. (358 aa)
	G7K_1845-t1	TFIIB-type domain-containing protein. (465 aa)
	G7K_2172-t1	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (468 aa)
	G7K_2362-t1	Histone H2A; Belongs to the histone H2A family. (202 aa)
	G7K_2363-t1	Histone H2B; Belongs to the histone H2B family. (175 aa)
	G7K_2421-t1	Histone H2B; Belongs to the histone H2B family. (195 aa)
	G7K_2803-t1	Uncharacterized protein. (1007 aa)
	G7K_3149-t1	Uncharacterized protein. (436 aa)
	G7K_2781-t1	Fe2OG dioxygenase domain-containing protein. (417 aa)
	G7K_3376-t1	DNA helicase; Belongs to the MCM family. (1810 aa)
	G7K_3349-t1	Uncharacterized protein. (870 aa)
	G7K_3504-t1	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (767 aa)
	G7K_3376-t2	DNA helicase; Belongs to the MCM family. (1830 aa)
	G7K_3807-t1	DNA polymerase. (1132 aa)
	G7K_3670-t1	Uncharacterized protein. (196 aa)
	G7K_4006-t1	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (171 aa)
	PIF1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (951 aa)
	G7K_4169-t1	Uncharacterized protein. (137 aa)
	G7K_4042-t1	DNA_pol_E_B domain-containing protein. (830 aa)
	G7K_4032-t1	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (604 aa)
	G7K_4466-t1	AAA domain-containing protein. (348 aa)
	G7K_4160-t1	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (641 aa)
	G7K_4304-t1	Uncharacterized protein. (925 aa)
	G7K_4791-t1	Uncharacterized protein. (489 aa)
	G7K_4699-t1	Histone H3; Belongs to the histone H3 family. (137 aa)
	G7K_5159-t1	Sld5 domain-containing protein. (179 aa)
	G7K_5135-t1	Uncharacterized protein. (797 aa)
	G7K_5842-t1	Aminotran_5 domain-containing protein. (394 aa)
	G7K_5467-t1	Cell division control protein; Belongs to the CDC6/cdc18 family. (483 aa)
	G7K_6447-t1	Uncharacterized protein. (128 aa)
	G7K_6299-t1	Uncharacterized protein. (311 aa)
	G7K_6088-t1	DUF2236 domain-containing protein. (467 aa)
	G7K_6142-t1	Uncharacterized protein. (972 aa)
	G7K_6612-t1	CENP-T_C domain-containing protein. (454 aa)
	G7K_6566-t1	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (239 aa)

Your Current Organism:

Saitoella complicata

NCBI taxonomy Id: 698492
Other names: S. complicata NRRL Y-17804, Saitoella complicata CBS 7301, Saitoella complicata CCRC 22490, Saitoella complicata IAM 12963, Saitoella complicata JCM 7358, Saitoella complicata NBRC 10748, Saitoella complicata NRRL Y-17804

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G7K_0057-t1	G7K_0194-t1	A0A0E9N792	A0A0E9N7Z7	DNA polymerase.	Uncharacterized protein.	0.706
G7K_0057-t1	G7K_0289-t1	A0A0E9N792	A0A0E9N8M0	DNA polymerase.	DNA helicase; Belongs to the MCM family.	0.961
G7K_0057-t1	G7K_0533-t1	A0A0E9N792	A0A0E9N995	DNA polymerase.	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	0.638
G7K_0057-t1	G7K_1043-t1	A0A0E9N792	A0A0E9NBQ2	DNA polymerase.	Uncharacterized protein.	0.992
G7K_0057-t1	G7K_1051-t1	A0A0E9N792	A0A0E9NAJ2	DNA polymerase.	RPA_C domain-containing protein.	0.872
G7K_0057-t1	G7K_1075-t1	A0A0E9N792	A0A0E9NAE4	DNA polymerase.	DNA polymerase.	0.928
G7K_0057-t1	G7K_1675-t1	A0A0E9N792	A0A0E9NCE3	DNA polymerase.	Uncharacterized protein.	0.735
G7K_0057-t1	G7K_2147-t1	A0A0E9N792	A0A0E9NDS2	DNA polymerase.	AAA domain-containing protein.	0.849
G7K_0057-t1	G7K_2172-t1	A0A0E9N792	A0A0E9NE58	DNA polymerase.	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	0.974
G7K_0057-t1	G7K_3349-t1	A0A0E9N792	A0A0E9NHM1	DNA polymerase.	Uncharacterized protein.	0.548
G7K_0057-t1	G7K_3376-t1	A0A0E9N792	A0A0E9NHA7	DNA polymerase.	DNA helicase; Belongs to the MCM family.	0.933
G7K_0057-t1	G7K_3376-t2	A0A0E9N792	A0A0E9NII0	DNA polymerase.	DNA helicase; Belongs to the MCM family.	0.933
G7K_0057-t1	G7K_3504-t1	A0A0E9N792	A0A0E9NHP6	DNA polymerase.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.901
G7K_0057-t1	G7K_3670-t1	A0A0E9N792	A0A0E9NIM1	DNA polymerase.	Uncharacterized protein.	0.809
G7K_0057-t1	G7K_4032-t1	A0A0E9N792	A0A0E9NKH8	DNA polymerase.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.921
G7K_0057-t1	G7K_4042-t1	A0A0E9N792	A0A0E9NJQ2	DNA polymerase.	DNA_pol_E_B domain-containing protein.	0.964
G7K_0057-t1	G7K_4160-t1	A0A0E9N792	A0A0E9NKT8	DNA polymerase.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.969
G7K_0057-t1	G7K_4304-t1	A0A0E9N792	A0A0E9NL79	DNA polymerase.	Uncharacterized protein.	0.650
G7K_0057-t1	G7K_4466-t1	A0A0E9N792	A0A0E9NKJ2	DNA polymerase.	AAA domain-containing protein.	0.801
G7K_0057-t1	G7K_4791-t1	A0A0E9N792	A0A0E9NLE4	DNA polymerase.	Uncharacterized protein.	0.999

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