STRINGSTRING
G7K_1065-t1 G7K_1065-t1 G7K_0299-t1 G7K_0299-t1 G7K_0534-t1 G7K_0534-t1 G7K_0700-t1 G7K_0700-t1 G7K_0945-t1 G7K_0945-t1 G7K_1034-t1 G7K_1034-t1 MDM34 MDM34 G7K_1541-t1 G7K_1541-t1 G7K_1698-t1 G7K_1698-t1 G7K_2215-t1 G7K_2215-t1 G7K_2348-t1 G7K_2348-t1 G7K_2389-t1 G7K_2389-t1 G7K_2417-t1 G7K_2417-t1 G7K_2591-t1 G7K_2591-t1 G7K_2519-t1 G7K_2519-t1 G7K_2534-t1 G7K_2534-t1 DRE2 DRE2 G7K_3045-t1 G7K_3045-t1 G7K_3065-t1 G7K_3065-t1 G7K_3226-t1 G7K_3226-t1 G7K_2984-t1 G7K_2984-t1 G7K_3736-t1 G7K_3736-t1 G7K_3871-t1 G7K_3871-t1 G7K_3750-t1 G7K_3750-t1 G7K_3985-t1 G7K_3985-t1 G7K_4000-t1 G7K_4000-t1 G7K_3863-t1 G7K_3863-t1 G7K_4032-t1 G7K_4032-t1 G7K_4185-t1 G7K_4185-t1 G7K_4592-t1 G7K_4592-t1 G7K_4517-t1 G7K_4517-t1 G7K_4762-t1 G7K_4762-t1 G7K_4551-t1 G7K_4551-t1 G7K_5058-t1 G7K_5058-t1 G7K_4871-t1 G7K_4871-t1 G7K_5553-t1 G7K_5553-t1 G7K_5677-t1 G7K_5677-t1 G7K_5933-t1 G7K_5933-t1 G7K_6034-t1 G7K_6034-t1 G7K_6272-t1 G7K_6272-t1 G7K_6093-t1 G7K_6093-t1 G7K_6142-t1 G7K_6142-t1 G7K_6593-t1 G7K_6593-t1 G7K_6884-t1 G7K_6884-t1 G7K_6779-t1 G7K_6779-t1 G7K_6771-t1 G7K_6771-t1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G7K_1065-t1Uncharacterized protein. (1317 aa)
G7K_0299-t1Protein kinase domain-containing protein. (625 aa)
G7K_0534-t1Uncharacterized protein. (1022 aa)
G7K_0700-t1Uncharacterized protein. (603 aa)
G7K_0945-t1Uncharacterized protein. (1419 aa)
G7K_1034-t1Protein kinase domain-containing protein. (521 aa)
MDM34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (416 aa)
G7K_1541-t1Non-specific serine/threonine protein kinase. (671 aa)
G7K_1698-t1Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2535 aa)
G7K_2215-t1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (463 aa)
G7K_2348-t1PIPK domain-containing protein. (868 aa)
G7K_2389-t1DUF1767 domain-containing protein. (230 aa)
G7K_2417-t1FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (563 aa)
G7K_2591-t1DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (645 aa)
G7K_2519-t1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (465 aa)
G7K_2534-t1PHD-type domain-containing protein. (381 aa)
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (645 aa)
G7K_3045-t1Uncharacterized protein. (265 aa)
G7K_3065-t1Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (793 aa)
G7K_3226-t1Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (351 aa)
G7K_2984-t1Uncharacterized protein. (764 aa)
G7K_3736-t1Uncharacterized protein. (1524 aa)
G7K_3871-t1Chromatin modification-related protein. (317 aa)
G7K_3750-t1Uncharacterized protein. (815 aa)
G7K_3985-t1Uncharacterized protein. (1609 aa)
G7K_4000-t1Protein kinase domain-containing protein. (788 aa)
G7K_3863-t1Uncharacterized protein. (1458 aa)
G7K_4032-t1Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (604 aa)
G7K_4185-t1Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2921 aa)
G7K_4592-t1Protein kinase domain-containing protein. (614 aa)
G7K_4517-t1Uncharacterized protein. (347 aa)
G7K_4762-t1Uncharacterized protein. (655 aa)
G7K_4551-t1Uncharacterized protein. (534 aa)
G7K_5058-t1Peptidyl-prolyl cis-trans isomerase. (177 aa)
G7K_4871-t1zf-4CXXC_R1 domain-containing protein. (818 aa)
G7K_5553-t1Uncharacterized protein. (178 aa)
G7K_5677-t1Uncharacterized protein. (602 aa)
G7K_5933-t1PHD domain-containing protein. (472 aa)
G7K_6034-t1TAF4 domain-containing protein. (516 aa)
G7K_6272-t1Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (375 aa)
G7K_6093-t1Uncharacterized protein. (891 aa)
G7K_6142-t1Uncharacterized protein. (972 aa)
G7K_6593-t1Protein kinase domain-containing protein. (937 aa)
G7K_6884-t1Protein kinase domain-containing protein. (1100 aa)
G7K_6779-t1Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2430 aa)
G7K_6771-t1Protein kinase domain-containing protein. (798 aa)
Your Current Organism:
Saitoella complicata
NCBI taxonomy Id: 698492
Other names: S. complicata NRRL Y-17804, Saitoella complicata CBS 7301, Saitoella complicata CCRC 22490, Saitoella complicata IAM 12963, Saitoella complicata JCM 7358, Saitoella complicata NBRC 10748, Saitoella complicata NRRL Y-17804
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