(46 nodes) Phosphorelay signal transduction system, and Diguanylate cyclase network (Rhizobium tropici)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AGB69492.1	Photosynthetic apparatus regulatory protein RegA. (195 aa)
	AGB69493.1	Sensor histidine kinase RegB. (445 aa)
	AGB69586.1	Two component transcriptional regulator, winged helix family. (239 aa)
	AGB69587.1	Signal transduction histidine kinase protein. (450 aa)
	AGB69595.1	Diguanylate cyclase. (262 aa)
	AGB69616.1	Diguanylate cyclase/phosphodiesterase. (780 aa)
	AGB69884.1	Two component sensor kinase/response regulator hybrid. (762 aa)
	AGB69939.1	Two-component sensor histidine kinase protein. (506 aa)
	AGB69959.1	Diguanylate cyclase. (384 aa)
	phoR	Phosphate regulon sensor kinase PhoR. (408 aa)
	phoB	Phosphate regulon transcriptional regulatory protein PhoB. (227 aa)
	AGB70138.1	Two component sensor kinase. (1221 aa)
	AGB70228.1	Two component sensor kinase. (577 aa)
	AGB70229.1	GGDEF domain-containing protein. (446 aa)
	AGB70294.1	Diguanylate cyclase. (345 aa)
	AGB70351.1	Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor. (970 aa)
	AGB70402.1	Diguanylate cyclase/phosphodiesterase. (601 aa)
	AGB70484.1	Histidine kinase. (503 aa)
	AGB70505.1	Transcriptional activator protein CopR. (225 aa)
	AGB70506.1	Two-component sensor histidine kinase protein. (471 aa)
	AGB70508.1	Multi-sensor signal transduction histidine kinase. (771 aa)
	AGB70752.1	Putative sensory BOX/GGDEF family protein. (417 aa)
	AGB70815.1	Cell division response regulator DivK. (164 aa)
	AGB70816.1	GGDEF domain-containing protein. (457 aa)
	AGB71374.1	Multi-sensor hybrid histidine kinase. (872 aa)
	AGB71425.1	GGDEF domain-containing protein. (355 aa)
	AGB71454.1	Integral membrane sensor signal transduction histidine kinase. (509 aa)
	AGB71534.1	Two component response regulator. (443 aa)
	AGB71535.1	Two-component response regulator protein. (279 aa)
	AGB71765.1	Response regulator receiver domain protein. (216 aa)
	AGB71766.1	Signal transduction histidine kinase. (354 aa)
	AGB71903.1	Two-component response regulator. (233 aa)
	AGB71904.1	Integral membrane sensor signal transduction histidine kinase. (435 aa)
	AGB72039.1	Two component sensor kinase/response regulator hybrid. (935 aa)
	AGB72077.1	DNA-binding response regulator. (128 aa)
	AGB72140.1	GGDEF domain-containing protein. (286 aa)
	AGB72165.1	Cell cycle transcriptional regulator CtrA. (233 aa)
	AGB72168.1	Hypothetical protein. (218 aa)
	AGB72199.1	Diguanylate cyclase/phosphodiesterase. (589 aa)
	AGB72419.1	Response regulator receiver protein. (121 aa)
	AGB72452.1	Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor. (771 aa)
	AGB72477.1	GGDEF domain-containing protein. (736 aa)
	AGB72640.1	Two component response regulator. (119 aa)
	AGB72815.1	Two component transcriptional regulator, winged helix family. (227 aa)
	AGB72859.1	DNA-binding response regulator TctD. (222 aa)
	AGB72860.1	Integral membrane sensor signal transduction histidine kinase. (471 aa)

Your Current Organism:

Rhizobium tropici

NCBI taxonomy Id: 698761
Other names: R. tropici CIAT 899, Rhizobium tropici CIAT 899, Rhizobium tropici str. CIAT 899, Rhizobium tropici strain CIAT 899

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGB69492.1	AGB69493.1	RTCIAT899_CH00295	RTCIAT899_CH00300	Photosynthetic apparatus regulatory protein RegA.	Sensor histidine kinase RegB.	0.994
AGB69492.1	AGB69939.1	RTCIAT899_CH00295	RTCIAT899_CH02610	Photosynthetic apparatus regulatory protein RegA.	Two-component sensor histidine kinase protein.	0.565
AGB69492.1	AGB71766.1	RTCIAT899_CH00295	RTCIAT899_CH11925	Photosynthetic apparatus regulatory protein RegA.	Signal transduction histidine kinase.	0.425
AGB69492.1	AGB72039.1	RTCIAT899_CH00295	RTCIAT899_CH13300	Photosynthetic apparatus regulatory protein RegA.	Two component sensor kinase/response regulator hybrid.	0.440
AGB69492.1	AGB72815.1	RTCIAT899_CH00295	RTCIAT899_CH17260	Photosynthetic apparatus regulatory protein RegA.	Two component transcriptional regulator, winged helix family.	0.574
AGB69492.1	phoB	RTCIAT899_CH00295	RTCIAT899_CH02870	Photosynthetic apparatus regulatory protein RegA.	Phosphate regulon transcriptional regulatory protein PhoB.	0.444
AGB69493.1	AGB69492.1	RTCIAT899_CH00300	RTCIAT899_CH00295	Sensor histidine kinase RegB.	Photosynthetic apparatus regulatory protein RegA.	0.994
AGB69493.1	AGB69939.1	RTCIAT899_CH00300	RTCIAT899_CH02610	Sensor histidine kinase RegB.	Two-component sensor histidine kinase protein.	0.654
AGB69493.1	AGB70505.1	RTCIAT899_CH00300	RTCIAT899_CH05485	Sensor histidine kinase RegB.	Transcriptional activator protein CopR.	0.454
AGB69493.1	AGB70816.1	RTCIAT899_CH00300	RTCIAT899_CH07065	Sensor histidine kinase RegB.	GGDEF domain-containing protein.	0.509
AGB69493.1	AGB71903.1	RTCIAT899_CH00300	RTCIAT899_CH12620	Sensor histidine kinase RegB.	Two-component response regulator.	0.439
AGB69493.1	AGB72039.1	RTCIAT899_CH00300	RTCIAT899_CH13300	Sensor histidine kinase RegB.	Two component sensor kinase/response regulator hybrid.	0.529
AGB69493.1	AGB72077.1	RTCIAT899_CH00300	RTCIAT899_CH13495	Sensor histidine kinase RegB.	DNA-binding response regulator.	0.467
AGB69493.1	AGB72165.1	RTCIAT899_CH00300	RTCIAT899_CH13935	Sensor histidine kinase RegB.	Cell cycle transcriptional regulator CtrA.	0.488
AGB69493.1	AGB72815.1	RTCIAT899_CH00300	RTCIAT899_CH17260	Sensor histidine kinase RegB.	Two component transcriptional regulator, winged helix family.	0.739
AGB69493.1	AGB72859.1	RTCIAT899_CH00300	RTCIAT899_CH17485	Sensor histidine kinase RegB.	DNA-binding response regulator TctD.	0.439
AGB69493.1	phoB	RTCIAT899_CH00300	RTCIAT899_CH02870	Sensor histidine kinase RegB.	Phosphate regulon transcriptional regulatory protein PhoB.	0.571
AGB69586.1	AGB69587.1	RTCIAT899_CH00800	RTCIAT899_CH00805	Two component transcriptional regulator, winged helix family.	Signal transduction histidine kinase protein.	0.964
AGB69586.1	AGB69884.1	RTCIAT899_CH00800	RTCIAT899_CH02335	Two component transcriptional regulator, winged helix family.	Two component sensor kinase/response regulator hybrid.	0.730
AGB69586.1	AGB69939.1	RTCIAT899_CH00800	RTCIAT899_CH02610	Two component transcriptional regulator, winged helix family.	Two-component sensor histidine kinase protein.	0.527