STRINGSTRING
SMB88522.1 SMB88522.1 radA radA SMB88527.1 SMB88527.1 SMB88567.1 SMB88567.1 SMB88572.1 SMB88572.1 SMB91089.1 SMB91089.1 SMB91095.1 SMB91095.1 mcsB mcsB SMB91833.1 SMB91833.1 SMB97138.1 SMB97138.1 SMB97141.1 SMB97141.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMB88522.1Putative hydrolase; InterPro IPR003141:IPR004013; COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; KEGG: mta:Moth_2491 putative hydrolase; SPTR: PHP-like; SMART: phosphoesterase PHP domain protein; PFAM: PHP domain protein. (246 aa)
radADNA repair protein RadA/Sms; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (460 aa)
SMB88527.1Uncharacterized conserved protein YacL, contains PIN and TRAM domains; InterPro IPR002792:IPR006596:IPR002716; COGs: COG4956 Integral membrane protein (PIN domain superfamily); KEGG: mta:Moth_2488 PilT protein-like; SPTR: PilT protein-like; SMART: Nucleotide binding protein PINc; PFAM: PilT protein domain protein; deoxyribonuclease/rho motif-related TRAM. (374 aa)
SMB88567.123S rRNA (guanosine2251-2'-O)-methyltransferase; InterPro IPR004441:IPR013123:IPR001537; COGs: COG0566 rRNA methylase; KEGG: mta:Moth_2481 RNA methyltransferase TrmH, group 3; SPTR: RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; TIGRFAM: RNA methyltransferase, TrmH family, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (256 aa)
SMB88572.1RNA polymerase, sigma 30 subunit, SigH; InterProIPR014218:IPR014284:IPR016371:IPR000792:IPR 000943:IPR007627:IPR013249; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; KEGG: mta:Moth_2479 RNA polymerase factor sigma-70; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; TIGRFAM: RNA polymerase sigma-H factor; RNA polymerase sigma factor, sigma-70 family. (214 aa)
SMB91089.1InterPro IPR008463; COGs: COG4463 Transcriptional repressor of class III stress genes; KEGG: mta:Moth_0159 transcriptional regulator; SPTR: Transcriptional regulator; PFAM: Firmicute transcriptional repressor of class III stress genes; Belongs to the CtsR family. (157 aa)
SMB91095.1Protein-arginine kinase activator protein McsA; InterPro IPR001943; COGs: COG3880 Uncharacterized protein with conserved CXXC pairs; KEGG: mta:Moth_0160 UvrB/UvrC protein; SPTR: UvrB/UvrC protein; PFAM: UvrB/UvrC protein. (168 aa)
mcsBProtein arginine kinase; Catalyzes the specific phosphorylation of arginine residues in proteins. (353 aa)
SMB91833.1KEGG: mta:Moth_0403 hypothetical protein; SPTR: Putative uncharacterized protein. (79 aa)
SMB97138.1KEGG: tcr:511001.170 hypothetical protein; SPTR: Putative uncharacterized protein. (221 aa)
SMB97141.1KEGG: dau:Daud_0816 DEAD/DEAH box helicase domain-containing protein; SPTR: DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; Protein of unknown function DUF1998; InterProIPR014021:IPR001650:IPR011545:IPR018973:IPR 014001; COGs: COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster. (755 aa)
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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