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| | SMB96779.1 | KEGG: cbb:CLD_2428 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated. (183 aa) |
| | cysS | cysteinyl-tRNA synthetase; InterPro IPR002308:IPR015803:IPR015273; COGs: COG0215 Cysteinyl-tRNA synthetase; KEGG: mta:Moth_2484 cysteinyl-tRNA synthetase; SPTR: Cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (489 aa) |
| | SMB88567.1 | 23S rRNA (guanosine2251-2'-O)-methyltransferase; InterPro IPR004441:IPR013123:IPR001537; COGs: COG0566 rRNA methylase; KEGG: mta:Moth_2481 RNA methyltransferase TrmH, group 3; SPTR: RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; TIGRFAM: RNA methyltransferase, TrmH family, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (256 aa) |
| | SMB88572.1 | RNA polymerase, sigma 30 subunit, SigH; InterProIPR014218:IPR014284:IPR016371:IPR000792:IPR 000943:IPR007627:IPR013249; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; KEGG: mta:Moth_2479 RNA polymerase factor sigma-70; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; TIGRFAM: RNA polymerase sigma-H factor; RNA polymerase sigma factor, sigma-70 family. (214 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (427 aa) |
| | nusG | Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. (175 aa) |
| | rpoB | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1150 aa) |
| | rpoC | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1160 aa) |
| | rpoA | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (313 aa) |
| | truA | tRNA pseudouridine38-40 synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (246 aa) |
| | rlmH | 23S rRNA (pseudouridine1915-N3)-methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (154 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (309 aa) |
| | rsmI | 16S rRNA (cytidine1402-2'-O)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (276 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (640 aa) |
| | rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (295 aa) |
| | SMB89506.1 | Sigma-70, region 4; InterPro IPR000792:IPR013249; KEGG: mta:Moth_0090 sigma-24 (FecI-like); SPTR: Sigma-24 (FecI-like); PFAM: Sigma-70 region 4 type 2. (74 aa) |
| | SMB89601.1 | RNA polymerase, sigma-24 subunit, RpoE; InterPro IPR014284:IPR000838:IPR007627:IPR013249; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; KEGG: mta:Moth_2362 sigma-24 (FecI-like); SPTR: RNA polymerase sigma factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. (208 aa) |
| | SMB89873.1 | RNA polymerase sigma-70 factor, ECF subfamily; InterPro IPR014284:IPR007627:IPR013249; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; KEGG: dau:Daud_2125 ECF subfamily RNA polymerase sigma-24 factor; SPTR: RNA polymerase sigma factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family. (227 aa) |
| | SMB90200.1 | Methyltransferase, FkbM family; InterPro IPR013216; KEGG: mta:Moth_1645 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Methyltransferase type 11. (295 aa) |
| | SMB90348.1 | NOL1/NOP2/sun family putative RNA methylase; InterPro IPR018314:IPR001678; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; KEGG: adg:Adeg_1267 Fmu (Sun) domain protein; SPTR: Fmu (Sun) domain protein; PFAM: Fmu (Sun) domain protein. (484 aa) |
| | SMB91049.1 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; InterPro IPR003442; COGs: COG0802 ATPase or kinase; KEGG: mta:Moth_2160 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0079, ATPase. (152 aa) |
| | SMB91055.1 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaB; InterPro IPR000905; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; KEGG: mta:Moth_2159 peptidase M22, glycoprotease; SPTR: Peptidase M22, glycoprotease; PFAM: peptidase M22 glycoprotease. (228 aa) |
| | tsaD | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (336 aa) |
| | SMB91152.1 | InterPro IPR002646:IPR006674:IPR006675; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; KEGG: tde:TDE1033 polyA polymerase family protein; SPTR: PolyA polymerase family protein; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; TIGRFAM: metal dependent phophohydrolase. (457 aa) |
| | SMB91254.1 | Predicted nucleic acid-binding protein, contains PIN domain; InterPro IPR002716; KEGG: mta:Moth_0685 PilT protein-like; PFAM: PilT protein domain protein; SPTR: PilT protein-like. (149 aa) |
| | thiI | Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (384 aa) |
| | SMB91526.1 | RNA polymerase, sigma 54 subunit, RpoN/SigL; InterPro IPR000394:IPR007046:IPR007634; COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; KEGG: mta:Moth_0261 sigma-54 (RpoN); SPTR: Sigma-54 (RpoN); PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN. (465 aa) |
| | rnr | RNAse R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (707 aa) |
| | SMB91802.1 | TusA-related sulfurtransferase; KEGG: pai:PAE2602 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: SirA-like domain-containing protein; InterPro IPR013838:IPR001455; Belongs to the sulfur carrier protein TusA family. (84 aa) |
| | SMB91839.1 | Ribonuclease BN, tRNA processing enzyme; COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; KEGG: metal-dependent hydrolase; SPTR: Putative uncharacterized protein. (244 aa) |
| | SMB92484.1 | Epoxyqueuosine reductase; Contains selenocysteine; InterPro IPR017896:IPR004155:IPR013542:IPR017900; COGs: COG1600 Uncharacterized Fe-S protein; KEGG: mta:Moth_0507 4Fe-4S ferredoxin, iron-sulfur binding; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: domain of unknown function DUF1730; PBS lyase HEAT domain protein repeat-containing protein; manually curated. (366 aa) |
| | rph | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (249 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (888 aa) |
| | leuS | leucyl-tRNA synthetase; InterPro IPR015413:IPR013155:IPR002302:IPR001412; COGs: COG0495 Leucyl-tRNA synthetase; KEGG: mta:Moth_0568 leucyl-tRNA synthetase; SPTR: Leucyl-tRNA synthetase; PFAM: tRNA synthetase valyl/leucyl anticodon-binding; tRNA synthetase class I (M); TIGRFAM: leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (831 aa) |
| | SMB92920.1 | 16S rRNA (uracil1498-N3)-methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (252 aa) |
| | SMB92931.1 | Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB; InterProIPR002792:IPR013848:IPR006638:IPR007197:IPR 005839:IPR006467:IPR020612; COGs: COG0621 2-methylthioadenine synthetase; KEGG: mta:Moth_0588 MiaB-like tRNA modifying enzyme; SPTR: MiaB-like tRNA modifying enzyme; SMART: Elongator protein 3/MiaB/NifB; PFAM: protein of unknown function UPF0004; Radical SAM domain protein; deoxyribonuclease/rho motif-related TRAM; TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme. (434 aa) |
| | ybeY | Probable rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (156 aa) |
| | glyQ | InterPro IPR006194:IPR002310; COGs: COG0752 Glycyl-tRNA synthetase alpha subunit; KEGG: mta:Moth_0603 glycyl-tRNA synthetase subunit alpha; SPTR: Glycyl-tRNA synthetase alpha subunit; PFAM: glycyl-tRNA synthetase alpha subunit; PRIAM: Glycine--tRNA ligase; TIGRFAM: glycyl-tRNA synthetase, alpha subunit. (331 aa) |
| | glyS | glycyl-tRNA synthetase beta chain; InterPro IPR006194:IPR015944:IPR002311:IPR008909; COGs: COG0751 Glycyl-tRNA synthetase beta subunit; KEGG: mta:Moth_0604 glycyl-tRNA synthetase, beta subunit; SPTR: Glycyl-tRNA synthetase beta subunit; PFAM: glycyl-tRNA synthetase beta subunit; DALR anticodon binding domain protein; PRIAM: Glycine--tRNA ligase; TIGRFAM: glycyl-tRNA synthetase, beta subunit. (696 aa) |
| | rnhA | RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (151 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (607 aa) |
| | sigA | RNA polymerase primary sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (363 aa) |
| | SMB93130.1 | tRNA (adenine22-N1)-methyltransferase; InterPro IPR006901:IPR000408; COGs: COG2384 SAM-dependent methyltransferase; KEGG: mta:Moth_0625 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: protein of unknown function DUF633. (242 aa) |
| | vapC | PIN domain nuclease, a component of toxin-antitoxin system (PIN domain); Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (136 aa) |
| | vapC-2 | Hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (134 aa) |
| | SMB93488.1 | tRNA pseudouridine13 synthase; InterPro IPR011760:IPR001656; COGs: COG0585 conserved hypothetical protein; KEGG: mta:Moth_1745 pseudouridylate synthase; SPTR: Pseudouridylate synthase; PFAM: tRNA pseudouridine synthase D TruD. (388 aa) |
| | SMB93515.1 | TusA-related sulfurtransferase; InterPro IPR001455; KEGG: mta:Moth_0447 SirA-like; SPTR: SirA-like; PFAM: SirA-like domain-containing protein; Belongs to the sulfur carrier protein TusA family. (75 aa) |
| | SMB94093.1 | RNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; InterProIPR014284:IPR012845:IPR007627:IPR007624:IPR 007630:IPR000943; COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; KEGG: mta:Moth_0794 sigma 28 (flagella/sporulation); SPTR: RNA polymerase sigma factor; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family. (252 aa) |
| | SMB94227.1 | InterPro IPR013027:IPR001327; KEGG: mta:Moth_0819 glucose-inhibited division protein A; SPTR: Glucose-inhibited division protein A; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (427 aa) |
| | rsmH | 16S rRNA (cytosine1402-N4)-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (302 aa) |
| | SMB94389.1 | RNA polymerase, sigma 29 subunit, SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (241 aa) |
| | SMB94393.1 | RNA polymerase, sigma subunit, RpsG/SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (257 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (940 aa) |
| | SMB94463.1 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (304 aa) |
| | pyrR | Pyrimidine operon attenuation protein / uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (185 aa) |
| | SMB94566.1 | TIGR00255 family protein; InterPro IPR005229:IPR013527:IPR013551; COGs: COG1561 Uncharacterized stress-induced protein; KEGG: mta:Moth_0890 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: YicC-like domain-containing protein; domain of unknown function DUF1732. (293 aa) |
| | rpoZ | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (67 aa) |
| | priA | Replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (737 aa) |
| | fmt-2 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (314 aa) |
| | SMB94623.1 | 16S rRNA (cytosine967-C5)-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (452 aa) |
| | rlmN | 23S rRNA (adenine2503-C2)-methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (380 aa) |
| | SMB94763.1 | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; InterPro IPR004398:IPR002052; COGs: COG0742 N6-adenine-specific methylase; KEGG: adg:Adeg_0116 methyltransferase; SPTR: Methyltransferase; PFAM: Conserved hypothetical protein CHP00095; TIGRFAM: methyltransferase. (186 aa) |
| | rnc | RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (236 aa) |
| | rimM | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (170 aa) |
| | trmD | tRNA (Guanine37-N(1)-) methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (249 aa) |
| | rnhB | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (199 aa) |
| | SMB95424.1 | Ribonuclease J; InterPro IPR011108; COGs: COG0595 hydrolase of the metallo-beta-lactamase superfamily; KEGG: dau:Daud_0808 beta-lactamase domain-containing protein; SPTR: Beta-lactamase domain protein; PFAM: RNA-metabolising metallo-beta-lactamase. (522 aa) |
| | trmFO | methylenetetrahydrofolate--tRNA-(uracil-5-)- methyltransferase; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (438 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (577 aa) |
| | nusA | NusA antitermination factor; Participates in both transcription termination and antitermination. (356 aa) |
| | rbfA | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (115 aa) |
| | truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (308 aa) |
| | pnp | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (739 aa) |
| | rnj | Ribonuclease J; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (554 aa) |
| | vapC-3 | Hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (132 aa) |
| | vapC-4 | Hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (132 aa) |
| | SMB96187.1 | Ribonuclease BN, tRNA processing enzyme; COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; KEGG: adg:Adeg_0700 beta-lactamase domain protein; SPTR: Beta-lactamase domain protein. (275 aa) |
| | SMB96283.1 | Replicative DNA helicase; InterPro IPR007694:IPR003593; COGs: COG0305 Replicative DNA helicase; KEGG: swo:Swol_1201 replicative DNA helicase-like protein; SPTR: DnaB domain protein helicase, C-terminal domain protein; SMART: AAA ATPase; PFAM: DnaB domain protein helicase domain protein. (443 aa) |
| | rnc-2 | RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (250 aa) |
| | SMB96648.1 | Sigma-70 region 2; InterPro IPR007627; KEGG: aac:Aaci_1081 RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; SPTR: RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; PFAM: sigma-70 region 2 domain protein; Belongs to the sigma-70 factor family. (159 aa) |
| | SMB96695.1 | RNA polymerase, sigma-24 subunit, RpoE; InterPro IPR000838:IPR014284:IPR007627:IPR013249; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; SPTR: RNA polymerase sigma factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; KEGG: mta:Moth_2362 sigma-24 (FecI-like); Belongs to the sigma-70 factor family. ECF subfamily. (207 aa) |
| | SMB96850.1 | Ribonuclease HI; InterPro IPR002156:IPR007527; COGs: COG0328 Ribonuclease HI; KEGG: iho:Igni_1153 ribonuclease H; SPTR: Ribonuclease H; PFAM: ribonuclease H. (218 aa) |
| | SMB96864.1 | Protein of unknown function; KEGG: tte:TTE2018 DNA primase; SPTR: DNA primase (Bacterial type). (454 aa) |
| | SMB96951.1 | Hypothetical protein; InterPro IPR002716; KEGG: adg:Adeg_0505 PilT protein domain protein; SPTR: PilT protein domain protein; PFAM: PilT protein domain protein. (109 aa) |
| | rimO | SSU ribosomal protein S12P methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (446 aa) |
| | rny | Metal dependent phosphohydrolase; Endoribonuclease that initiates mRNA decay. (510 aa) |
| | SMB97202.1 | Hypothetical protein; InterPro IPR004013:IPR003141; COGs: COG0613 metal-dependent phosphoesterase (PHP family); KEGG: mta:Moth_1085 PHP-like; SPTR: PHP-like; SMART: phosphoesterase PHP domain protein; PFAM: PHP domain protein. (283 aa) |
| | miaB | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (439 aa) |
| | miaA | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (325 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (483 aa) |
| | SMB97990.1 | Hypothetical protein; KEGG: eck:EC55989_3265 helicase; SPTR: Helicase. (108 aa) |
| | SMB97998.1 | Phosphoribosyl 1,2-cyclic phosphodiesterase; COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; KEGG: amt:Amet_2603 hypothetical protein; SPTR: Gp51. (238 aa) |
| | SMB98077.1 | DNA replication protein DnaD; InterPro IPR006343; COGs: COG3935 Putative primosome component and related protein; KEGG: mta:Moth_1185 DNA replication protein DnaD; SPTR: DNA replication protein DnaD; TIGRFAM: primosome, DnaD subunit. (248 aa) |
| | SMB98109.1 | TIGR00269 family protein; InterPro IPR012089:IPR011063; COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; KEGG: PP-loop domain protein; SPTR: PP-loop domain protein; PFAM: PP-loop domain protein; Belongs to the TtcA family. (302 aa) |
| | SMB98209.1 | mRNA interferase RelE/StbE; InterPro IPR007712; KEGG: aau:AAur_0707 addiction module toxin, RelE/StbE; SPTR: Addiction module toxin, RelE/StbE; PFAM: plasmid stabilization system. (92 aa) |
| | SMB98215.1 | InterPro IPR002716; COGs: COG4113 nucleic acid-binding protein contains PIN domain; KEGG: dau:Daud_2130 PilT domain-containing protein; SPTR: PilT protein domain protein; PFAM: PilT protein domain protein. (151 aa) |
| | SMB98241.1 | Uncharacterized conserved protein YutE, UPF0331/DUF86 family; InterPro IPR008201; COGs: COG2445 conserved hypothetical protein; KEGG: tga:TGAM_0986 nucleotidyltransferase substrate binding subunit, putative; SPTR: Putative uncharacterized protein; PFAM: protein of unknown function DUF86. (155 aa) |
| | SMB98364.1 | Ribosomal large subunit pseudouridine synthase B; InterPro IPR000748:IPR002942:IPR006145:IPR018496; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; KEGG: mta:Moth_1352 ribosomal large subunit pseudouridine synthase B; SPTR: Pseudouridine synthase; SMART: RNA-binding S4 domain protein; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; Belongs to the pseudouridine synthase RsuA family. (241 aa) |
| | SMB98450.1 | tryptophanyl-tRNA synthetase; InterPro IPR002306:IPR002305:IPR001412; COGs: COG0180 Tryptophanyl-tRNA synthetase; KEGG: tryptophanyl-tRNA synthetase; SPTR: Tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; PRIAM: Tryptophan--tRNA ligase; TIGRFAM: tryptophanyl-tRNA synthetase. (329 aa) |
| | SMB98535.1 | RNA polymerase, sigma subunit, RpoX/SigF; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (255 aa) |
| | SMB98574.1 | N6-L-threonylcarbamoyladenine synthase; InterPro IPR000905:IPR017861; COGs: COG0533 Metal-dependent protease with possible chaperone activity; KEGG: mta:Moth_1520 O-sialoglycoprotein endopeptidase; SPTR: O-sialoglycoprotein endopeptidase; PFAM: peptidase M22 glycoprotease. (317 aa) |
| | nusB | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (140 aa) |
| | SMB98631.1 | InterPro IPR007630:IPR000943; KEGG: RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; SPTR: RNA polymerase sigma factor; PFAM: sigma-70 region 4 domain protein; COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit. (183 aa) |
| | SMB98664.1 | InterPro IPR000943:IPR007627; KEGG: mta:Moth_1582 sporulation sigma factor SigK; SPTR: RNA polymerase sigma factor; PFAM: sigma-70 region 2 domain protein; COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit. (116 aa) |
| | SMB98690.1 | tRNA 2-thiouridine synthesizing protein E; KEGG: mta:Moth_1631 putative sulfite reductase subunit protein; SPTR: Putative sulfite reductase subunit protein. (84 aa) |
| | SMB98691.1 | tRNA 2-thiouridine synthesizing protein E; InterPro IPR007453; COGs: COG2920 Dissimilatory sulfite reductase (desulfoviridin) gamma subunit; KEGG: mta:Moth_1632 DsrC-like protein; SPTR: DsrC-like protein; PFAM: DsrC family protein; TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family. (105 aa) |
| | SMB98709.1 | Sulfurtransferase TusA; InterPro IPR001455; KEGG: SirA family protein; SPTR: Similar to response regulator sirA; PFAM: SirA-like domain-containing protein; Belongs to the sulfur carrier protein TusA family. (79 aa) |
| | SMB98717.1 | Putative holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (141 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (889 aa) |
| | psuG | Pseudouridine-5'-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (312 aa) |
| | cas2 | CRISPR-associated protein, Cas2 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (87 aa) |
| | mnmA | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (371 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (606 aa) |
| | hisS | histidyl-tRNA synthetase; InterProIPR006195:IPR015807:IPR004516:IPR002314:IPR 004154; COGs: COG0124 Histidyl-tRNA synthetase; KEGG: mta:Moth_1677 histidyl-tRNA synthetase; SPTR: Histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; PRIAM: Histidine--tRNA ligase; TIGRFAM: histidyl-tRNA synthetase. (423 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (149 aa) |
| | tgt | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (378 aa) |
| | sigI | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; Belongs to the sigma-70 factor family. SigI subfamily. (237 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (404 aa) |
| | SMB98943.1 | Protein of unknown function; KEGG: mta:Moth_1855 hypothetical protein; SPTR: Putative uncharacterized protein. (143 aa) |
| | pheT | phenylalanyl-tRNA synthetase beta subunit; InterProIPR002547:IPR005121:IPR004532:IPR005146:IPR 005147; COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; KEGG: mta:Moth_1750 phenylalanyl-tRNA synthetase beta subunit; SPTR: Phenylalanyl-tRNA synthetase beta chain; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; PRIAM: Phenylalanine--tRNA ligase; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. (807 aa) |
| | pheS | phenylalanyl-tRNA synthetase, alpha subunit; InterPro IPR006195:IPR004529:IPR004188:IPR002319; COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; KEGG: mta:Moth_1751 phenylalanyl-tRNA synthetase, alpha subunit; SPTR: Phenylalanyl-tRNA synthetase alpha chain; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (342 aa) |
| | SMB98964.1 | RNA methyltransferase, TrmH family; InterPro IPR013123:IPR001537; COGs: COG0566 rRNA methylase; KEGG: mta:Moth_1753 tRNA/rRNA methyltransferase (SpoU); SPTR: tRNA/rRNA methyltransferase (SpoU); PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (256 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (634 aa) |
| | SMB99007.1 | CxxC-x17-CxxC domain-containing protein; KEGG: mta:Moth_0369 hypothetical protein; SPTR: Putative uncharacterized protein. (99 aa) |
| | SMB99009.1 | tRNA (adenine57-N1/adenine58-N1)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. (257 aa) |
| | SMB99023.1 | Predicted nucleic acid-binding protein, contains PIN domain; InterPro IPR002716; KEGG: gur:Gura_0169 PilT domain-containing protein; SPTR: PilT protein-like; PFAM: PilT protein domain protein. (157 aa) |
| | rtcB | tRNA-splicing ligase RtcB; InterPro IPR001233; COGs: COG1690 conserved hypothetical protein; KEGG: protein of unknown function UPF0027; SPTR: Putative uncharacterized protein; PFAM: protein of unknown function UPF0027; Belongs to the RtcB family. (478 aa) |
| | SMB99154.1 | InterPro IPR000824; KEGG: mta:Moth_1870 transcription attenuation protein MtrB; SPTR: Tryptophan RNA-binding attenuator protein; PFAM: tryptophan RNA-binding attenuator protein. (76 aa) |
| | SMB99244.1 | tRNA (cytidine/uridine-2'-O-)-methyltransferase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (154 aa) |
| | SMB99274.1 | COGs: COG3330 conserved hypothetical protein; KEGG: mta:Moth_1914 hypothetical protein; SPTR: Putative uncharacterized protein. (198 aa) |
| | SMB99331.1 | COGs: COG1600 Uncharacterized Fe-S protein; KEGG: dau:Daud_0137 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein. (268 aa) |
| | SMB99366.1 | RNA polymerase sigma-70 factor, ECF subfamily; InterPro IPR000838:IPR007627:IPR013249:IPR014284; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; KEGG: sth:STH907 RNA polymerase factor sigma C; SPTR: RNA polymerase sigma factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. (181 aa) |
| | SMB99652.1 | tRNA 2-thiouridine synthesizing protein A; InterPro IPR001455; KEGG: mta:Moth_1439 SirA-like; SPTR: SirA-like; PFAM: SirA-like domain-containing protein; Belongs to the sulfur carrier protein TusA family. (72 aa) |
| | SMB99739.1 | PIN domain-containing protein; InterPro IPR002716; KEGG: pth:PTH_0364 nucleic acid-binding protein; SPTR: Predicted nucleic acid-binding protein; PFAM: PilT protein domain protein. (110 aa) |
| | SMB99894.1 | TusA-related sulfurtransferase; InterPro IPR001455; KEGG: fpl:Ferp_2460 SirA family protein; SPTR: SirA family protein; PFAM: SirA-like domain-containing protein; Belongs to the sulfur carrier protein TusA family. (80 aa) |
| | lysS | lysyl-tRNA synthetase, class II; InterProIPR004365:IPR004364:IPR018149:IPR006195:IPR 002313; COGs: COG1190 Lysyl-tRNA synthetase (class II); KEGG: mta:Moth_0152 lysyl-tRNA synthetase; SPTR: Lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; TIGRFAM: lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (487 aa) |
| | SMB99981.1 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (334 aa) |
| | SMB99987.1 | tRNA(Ile)-lysidine synthase TilS/MesJ; InterPro IPR011063:IPR012089; COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; KEGG: pth:PTH_2665 ATPase; SPTR: Predicted ATPase; PFAM: PP-loop domain protein; Belongs to the TtcA family. (251 aa) |
| | SMB99989.1 | KEGG: chy:CHY_2453 hypothetical protein; SPTR: Putative uncharacterized protein. (213 aa) |
| | SMC00021.1 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (444 aa) |
| | SMC00042.1 | Selenium metabolism protein YedF; InterPro IPR001455:IPR019870; KEGG: mta:Moth_0124 SirA-like; SPTR: SirA-like; PFAM: SirA-like domain-containing protein; TIGRFAM: selenium metabolism protein YedF; Belongs to the sulfur carrier protein TusA family. (193 aa) |
| | SMC00060.1 | 23S rRNA (uracil1939-C5)-methyltransferase; InterPro IPR010280:IPR002792:IPR007848:IPR001566; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; KEGG: afn:Acfer_1736 RNA methyltransferase, TrmA family; PFAM: deoxyribonuclease/rho motif-related TRAM; methyltransferase small; TIGRFAM: RNA methyltransferase, TrmA family; SPTR: RNA methyltransferase, TrmA family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (444 aa) |
| | tilS | tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (461 aa) |
| | SMC00113.1 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (356 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (500 aa) |
| | argS | arginyl-tRNA synthetase; InterProIPR001412:IPR005148:IPR015945:IPR008909:IPR 001278; COGs: COG0018 Arginyl-tRNA synthetase; KEGG: mta:Moth_2410 arginyl-tRNA synthetase; SPTR: Arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; TIGRFAM: arginyl-tRNA synthetase. (560 aa) |
| | selA | L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (467 aa) |
| | SMC00165.1 | Hypothetical protein; InterPro IPR002716; COGs: COG1487 nucleic acid-binding protein contains PIN domain; KEGG: adg:Adeg_0505 PilT protein domain protein; SPTR: PilT protein domain protein; PFAM: PilT protein domain protein. (109 aa) |
| | rsmG | 16S rRNA (guanine527-N7)-methyltransferase; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (242 aa) |
| | mnmG | tRNA uridine 5-carboxymethylaminomethyl modification enzyme; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (633 aa) |
| | mnmE | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (459 aa) |
| | rnpA | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (122 aa) |
