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ADO46405.1 ADO46405.1 ADO46406.1 ADO46406.1 arnB arnB arnC arnC arnA arnA arnD arnD arnT arnT arnE arnE arnF arnF ADO46849.1 ADO46849.1 ADO46850.1 ADO46850.1 ADO47888.1 ADO47888.1 ADO47889.1 ADO47889.1 ADO47890.1 ADO47890.1 ADO47891.1 ADO47891.1 ADO47892.1 ADO47892.1 ADO47893.1 ADO47893.1 ADO47894.1 ADO47894.1 ADO47895.1 ADO47895.1 ADO47896.1 ADO47896.1 gmd gmd fcl fcl gmm gmm ADO47900.1 ADO47900.1 ADO47901.1 ADO47901.1 ADO47902.1 ADO47902.1 ADO47903.1 ADO47903.1 ADO47904.1 ADO47904.1 ADO47905.1 ADO47905.1 ADO47906.1 ADO47906.1 ADO47907.1 ADO47907.1 ADO47909.1 ADO47909.1 ADO47910.1 ADO47910.1 ADO47911.1 ADO47911.1 ADO47912.1 ADO47912.1 ADO47913.1 ADO47913.1 ADO47914.1 ADO47914.1 ADO47915.1 ADO47915.1 ADO47916.1 ADO47916.1 ADO47917.1 ADO47917.1 ADO47918.1 ADO47918.1 ADO47919.1 ADO47919.1 ADO47920.1 ADO47920.1 ADO47921.1 ADO47921.1 ADO47922.1 ADO47922.1 ADO47923.1 ADO47923.1 ADO47925.1 ADO47925.1 ADO47926.1 ADO47926.1 ADO49974.1 ADO49974.1 ADO49975.1 ADO49975.1 ADO49976.1 ADO49976.1 ADO49977.1 ADO49977.1 ADO49978.1 ADO49978.1 ADO49979.1 ADO49979.1 ADO49980.1 ADO49980.1 ADO49981.1 ADO49981.1 ADO49982.1 ADO49982.1 ADO49983.1 ADO49983.1 ADO50468.1 ADO50468.1 wecG wecG wzyE wzyE wecF wecF wzxE wzxE wecE wecE wecD wecD wecC wecC wecB wecB wzzE wzzE wecA wecA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ADO46405.1PFAM: glycosyl transferase family 2; KEGG: ctu:Ctu_41250 hypothetical protein. (289 aa)
ADO46406.1KEGG: ctu:Ctu_41240 hypothetical protein. (310 aa)
arnBDegT/DnrJ/EryC1/StrS aminotransferase; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily. (379 aa)
arnCGlycosyl transferase family 2; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. (327 aa)
arnANAD-dependent epimerase/dehydratase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP- L-Ara4N formyltransferase subfamily. (660 aa)
arnDPolysaccharide deacetylase; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily. (298 aa)
arnTGlycosyl transferase family 39; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. (551 aa)
arnEProtein of unknown function DUF6 transmembrane; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family. (112 aa)
arnFHypothetical protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family. (133 aa)
ADO46849.1KEGG: esa:ESA_03358 hypothetical protein; PFAM: ABC transporter related; SMART: AAA ATPase. (221 aa)
ADO46850.1PFAM: ABC-2 type transporter; KEGG: eum:ECUMN_3434 polysialic acid transport protein. (258 aa)
ADO47888.1PFAM: polysaccharide export protein; Soluble ligand binding domain; KEGG: cro:ROD_21981 putative polysaccharide export protein. (378 aa)
ADO47889.1KEGG: enc:ECL_03384 tyrosine phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight. (147 aa)
ADO47890.1TIGRFAM: capsular exopolysaccharide family; KEGG: enc:ECL_03383 tyrosine kinase; PFAM: lipopolysaccharide biosynthesis protein. (720 aa)
ADO47891.1PFAM: glycosyl transferase family 2; KEGG: cro:ROD_21951 putative glycosyl transferase. (281 aa)
ADO47892.1KEGG: esa:ESA_01160 putative colanic acid biosynthesis acetyltransferase WcaB; Belongs to the transferase hexapeptide repeat family. (163 aa)
ADO47893.1PFAM: glycosyl transferase group 1; KEGG: enc:ECL_03380 putative glycosyl transferase. (405 aa)
ADO47894.1KEGG: cro:ROD_21921 putative colanic acid polymerase. (407 aa)
ADO47895.1PFAM: glycosyl transferase family 2; KEGG: ctu:Ctu_27520 putative glycosyl transferase. (248 aa)
ADO47896.1KEGG: enc:ECL_03377 putative colanic acid biosynthesis acetyltransferase WcaF. (190 aa)
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (373 aa)
fclNAD-dependent epimerase/dehydratase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (321 aa)
gmmNUDIX hydrolase; Hydrolyzes GDP-mannose; Belongs to the Nudix hydrolase family. (159 aa)
ADO47900.1PFAM: glycosyl transferase group 1; KEGG: ent:Ent638_2664 putative glycosyl transferase. (407 aa)
ADO47901.1PFAM: Nucleotidyl transferase; mannose-6-phosphate isomerase type II; manually curated; KEGG: enc:ECL_03372 mannose-1-phosphate guanylyltransferase (GDP); TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. (478 aa)
ADO47902.1Phosphomannomutase; KEGG: enc:ECL_03371 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase. (475 aa)
ADO47903.1TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; KEGG: set:SEN2099 putative UDP-glucose lipid carrier transferase; PFAM: sugar transferase. (460 aa)
ADO47904.1PFAM: polysaccharide biosynthesis protein; KEGG: enc:ECL_03369 colanic acid exporter. (492 aa)
ADO47905.1KEGG: cro:ROD_21811 putative colanic acid biosynthesis pyruvyl transferase. (426 aa)
ADO47906.1PFAM: glycosyl transferase group 1; KEGG: ecm:EcSMS35_1018 colanic acid biosynthesis glycosyl transferase WcaL. (406 aa)
ADO47907.1KEGG: cko:CKO_00743 putative colanic acid biosynthesis protein. (468 aa)
ADO47909.1KEGG: spl:Spea_1398 dTDP-glucose 4,6 dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (362 aa)
ADO47910.1Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (293 aa)
ADO47911.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (293 aa)
ADO47912.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (184 aa)
ADO47913.1PFAM: ABC-2 type transporter; KEGG: gym:GYMC10_5817 ABC-2 type transporter. (258 aa)
ADO47914.1KEGG: neu:NE0483 polysaccharide ABC transporter ATPase; PFAM: ABC transporter related; SMART: AAA ATPase. (410 aa)
ADO47915.1PFAM: Capsule polysaccharide biosynthesis protein; transferase hexapeptide repeat containing protein; KEGG: bde:BDP_1853 acetyltransferase. (825 aa)
ADO47916.1PFAM: glycosyl transferase family 2; glycosyl transferase group 1; KEGG: asa:ASA_1441 glycosyl transferase, group 2 family protein. (687 aa)
ADO47917.1KEGG: asa:ASA_1443 glycosyltransferase. (363 aa)
ADO47918.1GtrA family protein; Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane. (116 aa)
ADO47919.1PFAM: glycosyl transferase family 2; KEGG: sea:SeAg_B0603 bactoprenol glucosyl transferase. (318 aa)
ADO47920.1KEGG: asa:ASA_1444 hypothetical protein. (463 aa)
ADO47921.1PFAM: acyltransferase 3; KEGG: asa:ASA_1445 O-antigen acetylase. (367 aa)
ADO47922.1TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: vvy:VV0341 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (376 aa)
ADO47923.1KEGG: pin:Ping_3458 glycosyltransferases-like protein. (248 aa)
ADO47925.1TIGRFAM: nucleotide sugar dehydrogenase; KEGG: sbo:SBO_0857 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (388 aa)
ADO47926.1PFAM: NAD-dependent epimerase/dehydratase; KEGG: ent:Ent638_2640 NAD-dependent epimerase/dehydratase. (334 aa)
ADO49974.1KEGG: ecz:ECS88_3322 capsule polysaccharide export inner-membrane protein. (390 aa)
ADO49975.1PFAM: polysaccharide export protein; KEGG: ecq:ECED1_3595 polysialic acid transport protein precursor. (556 aa)
ADO49976.1PFAM: Capsule polysaccharide biosynthesis protein; KEGG: ecq:ECED1_3597 capsule polysaccharide export protein. (674 aa)
ADO49977.1PFAM: Capsule polysaccharide biosynthesis protein; KEGG: ecq:ECED1_3598 capsule polysaccharide export protein. (416 aa)
ADO49978.1KEGG: bmq:BMQ_1137 hypothetical protein. (394 aa)
ADO49979.1PFAM: glycosyl transferase family 2; CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; KEGG: lmh:LMHCC_1548 glycosyl transferase, group 2 family protein. (764 aa)
ADO49980.1KEGG: svo:SVI_0622 hypothetical protein. (389 aa)
ADO49981.1KEGG: esa:ESA_03357 hypothetical protein. (365 aa)
ADO49982.1Manually curated; PFAM: ABC transporter related; KEGG: ecq:ECED1_3601 polysialic acid transport ATP-binding protein KpsT; SMART: AAA ATPase. (220 aa)
ADO49983.1ABC-2 type transporter; KEGG: ecq:ECED1_3602 polysialic acid transport protein; manually curated; PFAM: ABC-2 type transporter. (258 aa)
ADO50468.1PFAM: amino acid permease-associated region; KEGG: enc:ECL_04991 putative transport protein YifK. (461 aa)
wecGGlycosyl transferase, WecB/TagA/CpsF family; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis. (246 aa)
wzyEWzyE family protein; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. (450 aa)
wecF4-alpha-L-fucosyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. (359 aa)
wzxEPolysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. (416 aa)
wecETDP-4-keto-6-deoxy-D-glucose transaminase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family. (376 aa)
wecDTDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. (224 aa)
wecCNucleotide sugar dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. (420 aa)
wecBUDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. (361 aa)
wzzELipopolysaccharide biosynthesis protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. (348 aa)
wecAUndecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). (367 aa)
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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