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argE | KEGG: efe:EFER_3806 acetylornithine deacetylase; TIGRFAM: acetylornithine deacetylase (ArgE); PFAM: peptidase M20; peptidase dimerisation domain protein. (383 aa) | ||||
fabR | Regulatory protein TetR; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer. (211 aa) | ||||
argH | KEGG: enc:ECL_05028 argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase. (457 aa) | ||||
argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. (258 aa) | ||||
argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (334 aa) | ||||
ADO46307.1 | KEGG: enc:ECL_00034 acetolactate synthase catalytic subunit; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein. (562 aa) | ||||
ADO46308.1 | PFAM: amino acid-binding ACT domain protein; KEGG: enc:ECL_00035 acetolactate synthase 1 regulatory subunit. (95 aa) | ||||
ADO46331.1 | PFAM: GCN5-related N-acetyltransferase; KEGG: ent:Ent638_0041 GCN5-related N-acetyltransferase. (138 aa) | ||||
ADO46414.1 | TIGRFAM: serine O-acetyltransferase; KEGG: enc:ECL_00157 serine acetyltransferase; Belongs to the transferase hexapeptide repeat family. (273 aa) | ||||
ADO46522.1 | TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; KEGG: ssn:SSON_4202 aspartate kinase III; PFAM: aspartate/glutamate/uridylate kinase; Belongs to the aspartokinase family. (453 aa) | ||||
ADO46533.1 | PFAM: Beta-ketoacyl synthase; KEGG: cro:ROD_43251 putative beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (409 aa) | ||||
ADO46534.1 | KEGG: etr:ETAE_0824 3-ketoacyl-(acyl-carrier-protein) reductase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR. (243 aa) | ||||
ADO46536.1 | PFAM: Beta-ketoacyl synthase; KEGG: cro:ROD_43281 putative beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (389 aa) | ||||
ADO46542.1 | KEGG: cro:ROD_43341 putative acyl carrier protein dehydratase. (117 aa) | ||||
acpP | Phosphopantetheine-binding protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (83 aa) | ||||
ADO46546.1 | PFAM: phosphopantetheine-binding; KEGG: ent:Ent638_3886 putative acyl carrier protein. (85 aa) | ||||
ADO46548.1 | KEGG: ent:Ent638_3884 hypothetical protein. (239 aa) | ||||
ADO46563.1 | KEGG: ent:Ent638_3864 4-aminobutyrate aminotransferase; TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (421 aa) | ||||
panZ | GCN5-related N-acetyltransferase; Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion; Belongs to the PanZ/PanM family. (127 aa) | ||||
asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (368 aa) | ||||
bioH | bioH protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. (257 aa) | ||||
aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa) | ||||
aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (362 aa) | ||||
gph | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (253 aa) | ||||
argD | Succinylornithine transaminase family; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (407 aa) | ||||
ADO46652.1 | PFAM: alpha/beta hydrolase fold; KEGG: kpe:KPK_0378 putative hydrolase. (340 aa) | ||||
aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (272 aa) | ||||
ADO46728.1 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) | ||||
ADO46729.1 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (155 aa) | ||||
aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (150 aa) | ||||
argR | Arginine repressor, ArgR; Regulates arginine biosynthesis genes. (156 aa) | ||||
ADO46762.1 | KEGG: spq:SPAB_04154 glutamate synthase subunit beta; TIGRFAM: glutamate synthase, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (472 aa) | ||||
ADO46763.1 | KEGG: kpu:KP1_4936 glutamate synthase subunit alpha; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein. (1486 aa) | ||||
ADO46796.1 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (282 aa) | ||||
argG | TIGRFAM: argininosuccinate synthase; KEGG: cko:CKO_04574 argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (448 aa) | ||||
ADO46919.1 | KEGG: enc:ECL_02360 cystathionine beta-synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; CBS domain containing protein; SMART: CBS domain containing protein. (457 aa) | ||||
ADO46976.1 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (122 aa) | ||||
ADO47013.1 | KEGG: enc:ECL_04335 2,5-diketo-D-gluconate reductase A; PFAM: aldo/keto reductase. (275 aa) | ||||
ADO47044.1 | KEGG: dda:Dd703_0941 acyl carrier protein. (73 aa) | ||||
ADO47046.1 | PFAM: membrane bound O-acyl transferase MBOAT family protein; KEGG: eca:ECA3129 peptidoglycan biosynthesis protein; Belongs to the membrane-bound acyltransferase family. (372 aa) | ||||
ADO47114.1 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; KEGG: kpu:KP1_4635 D-3-phosphoglycerate dehydrogenase. (410 aa) | ||||
ADO47159.1 | Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: kpu:KP1_4527 DNA-binding transcriptional regulator LysR. (311 aa) | ||||
lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa) | ||||
argA | Amino-acid N-acetyltransferase; KEGG: enc:ECL_04141 N-acetylglutamate synthase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: aspartate/glutamate/uridylate kinase; GCN5-related N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily. (443 aa) | ||||
cysJ | Sulfite reductase (NADPH) flavoprotein, alpha chain; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family. (600 aa) | ||||
cysI | Sulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (570 aa) | ||||
ADO47236.1 | KEGG: ebi:EbC_21190 NapD-like protein. (331 aa) | ||||
ADO47291.1 | TIGRFAM: KpsF/GutQ family protein; KEGG: kpu:KP1_4308 D-arabinose 5-phosphate isomerase; PFAM: sugar isomerase (SIS); CBS domain containing protein. (321 aa) | ||||
ADO47418.1 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (356 aa) | ||||
ADO47419.1 | TIGRFAM: chorismate mutase; KEGG: cko:CKO_03920 bifunctional chorismate mutase/prephenate dehydrogenase; PFAM: Chorismate mutase, type II; Prephenate dehydrogenase. (373 aa) | ||||
ADO47420.1 | Chorismate mutase; KEGG: sbc:SbBS512_E2986 bifunctional chorismate mutase/prephenate dehydratase; TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase, type II. (386 aa) | ||||
acpS | Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (126 aa) | ||||
glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa) | ||||
ADO47524.1 | PFAM: thiamine pyrophosphate central domain-containing protein; thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: eic:NT01EI_2136 putative malonic semialdehyde oxidative decarboxylase; Belongs to the TPP enzyme family. (641 aa) | ||||
dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa) | ||||
dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (375 aa) | ||||
ADO47598.1 | Cysteine synthase B; Manually curated; TIGRFAM: cysteine synthase B; cysteine synthase; KEGG: enc:ECL_03749 cysteine synthase B (O-acetylserine sulfhydrolase B); PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. (303 aa) | ||||
ADO47605.1 | KEGG: enc:ECL_03744 cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. (323 aa) | ||||
cysZ | Putative sulfate transport protein CysZ; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family. (253 aa) | ||||
aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (361 aa) | ||||
ADO47663.1 | PFAM: Beta-ketoacyl synthase; KEGG: kpu:KP1_3963 3-oxoacyl-(acyl carrier protein) synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (404 aa) | ||||
ADO47667.1 | KEGG: enc:ECL_03668 aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase dimerisation region; Semialdehyde dehydrogenase NAD - binding; Belongs to the aspartate-semialdehyde dehydrogenase family. (337 aa) | ||||
accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (304 aa) | ||||
ADO47671.1 | FolC bifunctional protein; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. (422 aa) | ||||
ADO47851.1 | PFAM: glutamine synthetase catalytic region; KEGG: esa:ESA_04256 hypothetical protein. (468 aa) | ||||
ADO47892.1 | KEGG: esa:ESA_01160 putative colanic acid biosynthesis acetyltransferase WcaB; Belongs to the transferase hexapeptide repeat family. (163 aa) | ||||
ADO50564.1 | Aspartate kinase; KEGG: cko:CKO_03054 bifunctional aspartate kinase II/homoserine dehydrogenase II; TIGRFAM: aspartate kinase; PFAM: homoserine dehydrogenase; aspartate/glutamate/uridylate kinase; homoserine dehydrogenase NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. (810 aa) | ||||
ADO47925.1 | TIGRFAM: nucleotide sugar dehydrogenase; KEGG: sbo:SBO_0857 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (388 aa) | ||||
hisI | phosphoribosyl-ATP diphosphatase; KEGG: enc:ECL_03346 hypothetical protein; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase-like; phosphoribosyl-AMP cyclohydrolase; In the N-terminal section; belongs to the PRA-CH family. (199 aa) | ||||
hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (258 aa) | ||||
hisA | KEGG: kva:Kvar_1575 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. (245 aa) | ||||
hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (196 aa) | ||||
hisB | TIGRFAM: histidinol-phosphatase; histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: cko:CKO_00763 imidazole glycerol-phosphate dehydratase/histidinol phosphatase; PFAM: imidazoleglycerol-phosphate dehydratase; In the N-terminal section; belongs to the histidinol- phosphatase family. (355 aa) | ||||
hisC | KEGG: ent:Ent638_2633 histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (353 aa) | ||||
hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (434 aa) | ||||
hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. (299 aa) | ||||
ADO47969.1 | Glutamate--putrescine ligase; KEGG: cro:ROD_03561 gamma-glutamylputrescine synthetase; PFAM: glutamine synthetase catalytic region. (472 aa) | ||||
metJ | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. (105 aa) | ||||
ADO47994.1 | KEGG: xne:XNC1_1146 threonine-phosphate decarboxylase (L-threonine-O-3-phosphate decarboxylase); TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II. (370 aa) | ||||
ADO48182.1 | PFAM: NUDIX hydrolase; KEGG: kva:Kvar_1726 NUDIX hydrolase. (147 aa) | ||||
lpxM | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. (323 aa) | ||||
kdsA | KEGG: efe:EFER_1746 2-dehydro-3-deoxyphosphooctonate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA. (284 aa) | ||||
ADO48362.1 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (348 aa) | ||||
lpxP | Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (palmitoleoyl)-lipid IV(A); Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily. (304 aa) | ||||
fabV | Trans-2-enoyl-CoA reductase (NAD(+)); Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (397 aa) | ||||
ADO48491.1 | PFAM: GlpM family protein; KEGG: enc:ECL_02268 hypothetical protein. (111 aa) | ||||
ADO48506.1 | KEGG: spe:Spro_0026 beta-lactamase domain-containing protein. (266 aa) | ||||
ADO48561.1 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ent:Ent638_1939 3-hydroxy acid dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa) | ||||
bioD | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. (231 aa) | ||||
ADO48747.1 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cro:ROD_17111 enoyl-[acyl-carrier-protein] reductase (NADH). (262 aa) | ||||
ADO48761.1 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (891 aa) | ||||
ADO48773.1 | KEGG: kva:Kvar_3053 anthranilate synthase component I; TIGRFAM: anthranilate synthase component I; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein. (520 aa) | ||||
trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (531 aa) | ||||
trpC | PFAM: Indole-3-glycerol phosphate synthase; N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: enc:ECL_01727 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Belongs to the TrpC family. (452 aa) | ||||
trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (397 aa) | ||||
trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (269 aa) | ||||
ADO48779.1 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; KEGG: kva:Kvar_3063 alcohol dehydrogenase zinc-binding domain protein. (319 aa) | ||||
argD-2 | Succinylornithine transaminase family; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (406 aa) | ||||
ADO48809.1 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: cpi:Cpin_4299 bifunctional deaminase-reductase domain protein. (194 aa) | ||||
selD | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (347 aa) | ||||
ADO48945.1 | KEGG: kva:Kvar_3286 aminodeoxychorismate lyase; TIGRFAM: aminodeoxychorismate lyase; PFAM: aminotransferase class IV. (271 aa) | ||||
acpP-2 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa) | ||||
ADO48948.1 | 3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa) | ||||
ADO50556.1 | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; KEGG: cko:CKO_03051 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (296 aa) | ||||
ADO48949.1 | KEGG: kpu:KP1_2081 acyl carrier protein S-malonyltransferase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase. (309 aa) | ||||
fabH | 3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (317 aa) | ||||
asnA | TIGRFAM: aspartate/ammonia ligase; KEGG: enc:ECL_05137 asparagine synthetase AsnA; PFAM: aspartate--ammonia ligase. (330 aa) | ||||
plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (363 aa) | ||||
lpxL | Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (306 aa) | ||||
ADO49013.1 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. (1320 aa) | ||||
ADO49033.1 | KEGG: cro:ROD_34021 putative diaminopropionate ammonia-lyase; TIGRFAM: diaminopropionate ammonia-lyase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. (399 aa) | ||||
ADO49040.1 | KEGG: ecp:ECP_2872 putative selenate reductase subunit YgfK; TIGRFAM: selenate reductase YgfK; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (1034 aa) | ||||
ADO49066.1 | PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: dde:Dde_1373 (3R)-hydroxymyristoyl-ACP dehydratase. (146 aa) | ||||
fabA | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (172 aa) | ||||
aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (427 aa) | ||||
serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (362 aa) | ||||
serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (430 aa) | ||||
ADO49267.1 | PFAM: Glycosyl transferase, family 3-like; KEGG: cko:CKO_02322 glycosyl transferase family protein. (320 aa) | ||||
bioD-2 | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. (229 aa) | ||||
bioC | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. (251 aa) | ||||
bioF | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (384 aa) | ||||
bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (346 aa) | ||||
bioA | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (435 aa) | ||||
ADO49322.1 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (350 aa) | ||||
nadA | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (347 aa) | ||||
ADO49387.1 | KEGG: kpu:KP1_1645 asparagine synthetase B; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II. (554 aa) | ||||
lipA | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (321 aa) | ||||
mtnC | 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. (229 aa) | ||||
mtnD | Acireductone dioxygenase (Fe(2+)-requiring); Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (180 aa) | ||||
mtnA | Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (341 aa) | ||||
mtnK | 5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (399 aa) | ||||
folD | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (288 aa) | ||||
ADO49586.1 | PFAM: protein of unknown function DUF161; KEGG: ent:Ent638_0926 hypothetical protein. (202 aa) | ||||
ADO49603.1 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: enc:ECL_01206 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (348 aa) | ||||
ADO50613.1 | KEGG: enc:ECL_05111 glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp. (469 aa) | ||||
ADO49633.1 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (304 aa) | ||||
acpH | (Acyl-carrier-protein) phosphodiesterase; Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; Belongs to the AcpH family. (193 aa) | ||||
ADO49671.1 | PFAM: AroM family protein; KEGG: enc:ECL_01148 hypothetical protein. (225 aa) | ||||
aroL | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. (184 aa) | ||||
proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (269 aa) | ||||
proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (417 aa) | ||||
proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa) | ||||
ADO49776.1 | PFAM: aldo/keto reductase; KEGG: spq:SPAB_03360 2,5-diketo-D-gluconate reductase B. (267 aa) | ||||
accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa) | ||||
fabZ | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (151 aa) | ||||
dapD | TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; KEGG: sdy:SDY_0182 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (274 aa) | ||||
mtnN | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...] (232 aa) | ||||
ADO49833.1 | PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; manually curated; KEGG: enc:ECL_00946 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. (159 aa) | ||||
panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (263 aa) | ||||
panC | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (284 aa) | ||||
panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (126 aa) | ||||
ADO49888.1 | TIGRFAM: acetolactate synthase, small subunit; KEGG: kva:Kvar_4299 acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein. (163 aa) | ||||
ADO49889.1 | KEGG: kpe:KPK_4659 acetolactate synthase 3 catalytic subunit; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein. (574 aa) | ||||
leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (523 aa) | ||||
leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (363 aa) | ||||
ADO50581.1 | PFAM: dihydrodipicolinate synthetase; KEGG: cro:ROD_38421 putative lyase; Belongs to the DapA family. (297 aa) | ||||
leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (466 aa) | ||||
leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa) | ||||
ADO49916.1 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (159 aa) | ||||
carB | KEGG: enc:ECL_00840 carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; Belongs to the CarB family. (1074 aa) | ||||
carA | KEGG: cko:CKO_03351 carbamoyl phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. (382 aa) | ||||
dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa) | ||||
ADO49955.1 | TIGRFAM: threonine synthase; KEGG: cko:CKO_03383 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. (428 aa) | ||||
thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa) | ||||
ADO49957.1 | Aspartate kinase; KEGG: kpu:KP1_0820 bifunctional aspartokinase I/homeserine dehydrogenase I; TIGRFAM: aspartate kinase; PFAM: homoserine dehydrogenase; aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. (820 aa) | ||||
ADO49986.1 | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); KEGG: ect:ECIAI39_4920 phosphoserine phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase. (323 aa) | ||||
ADO50132.1 | PFAM: GCN5-related N-acetyltransferase; KEGG: cko:CKO_03549 hypothetical protein. (167 aa) | ||||
ADO50140.1 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (334 aa) | ||||
argR-2 | Arginine repressor, ArgR; Regulates arginine biosynthesis genes. (160 aa) | ||||
ADO50350.1 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (359 aa) | ||||
ubiC | Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway. (165 aa) | ||||
ADO50375.1 | TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; KEGG: cko:CKO_03894 aspartate kinase III; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (449 aa) | ||||
ADO50380.1 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1227 aa) | ||||
metAS | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. (309 aa) | ||||
metE | 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (753 aa) | ||||
ADO50441.1 | Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eum:ECUMN_4354 DNA-binding transcriptional activator, homocysteine-binding. (317 aa) | ||||
dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (274 aa) | ||||
ADO50464.1 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (246 aa) | ||||
ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (491 aa) | ||||
ilvA | Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (514 aa) | ||||
ilvD | TIGRFAM: dihydroxy-acid dehydratase; KEGG: sbc:SbBS512_E4149 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (616 aa) | ||||
ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (309 aa) | ||||
ADO50501.1 | KEGG: enc:ECL_05013 acetolactate synthase 2 regulatory subunit. (89 aa) | ||||
ADO50502.1 | Manually curated; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; KEGG: enc:ECL_05014 acetolactate synthase 2 catalytic subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein. (548 aa) |