STRINGSTRING
ADO46374.1 ADO46374.1 gpmI gpmI mdh mdh ADO47098.1 ADO47098.1 ADO47103.1 ADO47103.1 ADO47114.1 ADO47114.1 eno eno glyA glyA ADO47693.1 ADO47693.1 ackA ackA ADO47808.1 ADO47808.1 ADO47862.1 ADO47862.1 ADO48340.1 ADO48340.1 ADO48364.1 ADO48364.1 ADO48498.1 ADO48498.1 serC serC gpmA gpmA ADO49712.1 ADO49712.1 gpmB gpmB ADO49986.1 ADO49986.1 fbp fbp ADO50317.1 ADO50317.1 acs acs ppc ppc pfkA pfkA ADO50596.1 ADO50596.1 ADO50597.1 ADO50597.1 ADO50598.1 ADO50598.1 ADO50599.1 ADO50599.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADO46374.1TIGRFAM: fructose-1,6-bisphosphatase, class II; KEGG: cko:CKO_03075 fructose 1,6-bisphosphatase II; PFAM: GlpX family protein. (336 aa)
gpmIPhosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (515 aa)
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa)
ADO47098.1TIGRFAM: fructose-1,6-bisphosphatase, class II; KEGG: efe:EFER_2862 fructose-1,6-bisphosphatase II-like protein; PFAM: GlpX family protein. (323 aa)
ADO47103.1Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa)
ADO47114.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; KEGG: kpu:KP1_4635 D-3-phosphoglycerate dehydrogenase. (410 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (431 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
ADO47693.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (713 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
ADO47808.1S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (278 aa)
ADO47862.1PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: sdy:SDY_2270 fructose-bisphosphate aldolase. (349 aa)
ADO48340.11-phosphofructokinase; KEGG: kpu:KP1_3290 6-phosphofructokinase 2; TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family. (310 aa)
ADO48364.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)
ADO48498.1KEGG: kpu:KP1_3020 alcohol dehydrogenase class III; TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (372 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (362 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa)
ADO49712.16-phospho-3-hexuloisomerase; KEGG: seh:SeHA_C3252 3-hexulose-6-phosphate isomerase; PFAM: sugar isomerase (SIS). (186 aa)
gpmBPFAM: Phosphoglycerate mutase; KEGG: kpn:KPN_04850 phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (215 aa)
ADO49986.1TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); KEGG: ect:ECIAI39_4920 phosphoserine phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase. (323 aa)
fbpPFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: cko:CKO_03598 fructose-1,6-bisphosphatase. (332 aa)
ADO50317.1TIGRFAM: ketose-bisphosphate aldolase; KEGG: ent:Ent638_0285 hypothetical protein; PFAM: ketose-bisphosphate aldolase class-II. (286 aa)
acsacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (652 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (883 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
ADO50596.1Molybdopterin oxidoreductase Fe4S4 region; KEGG: ent:Ent638_4084 formate dehydrogenase; manually curated; PFAM: molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase. (195 aa)
ADO50597.1TIGRFAM: formate dehydrogenase, alpha subunit; KEGG: kva:Kvar_5033 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (804 aa)
ADO50598.1Formate dehydrogenase, beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (297 aa)
ADO50599.1TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: set:SEN3824 formate dehydrogenase-O subunit gamma. (211 aa)
Your Current Organism:
Enterobacter lignolyticus
NCBI taxonomy Id: 701347
Other names: Enterobacter lignolyticus SCF1, [. lignolyticus SCF1, [Enterobacter] lignolyticus SCF1
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