STRINGSTRING
chpB chpB PECL_1827 PECL_1827 addA addA addB addB rnpA rnpA ndoA ndoA PECL_288 PECL_288 dnaN dnaN PECL_377 PECL_377 PECL_382 PECL_382 xth xth PECL_444 PECL_444 mrnC mrnC holB holB uvrB uvrB uvrA uvrA rnr rnr PECL_567 PECL_567 PECL_595 PECL_595 dnaE dnaE PECL_676 PECL_676 rny rny PECL_721 PECL_721 yrrK yrrK mutS2 mutS2 PECL_92 PECL_92 polC polC rnhB rnhB rnmV rnmV ybeY ybeY nfo nfo PECL_1682 PECL_1682 PECL_1657 PECL_1657 PECL_1614 PECL_1614 PECL_1536 PECL_1536 rny-2 rny-2 PECL_1335 PECL_1335 PECL_1175 PECL_1175 PECL_1157 PECL_1157 polA polA PECL_1114 PECL_1114 xseA xseA xseB xseB rnc rnc dinG dinG PECL_102 PECL_102 recU recU PECL_781 PECL_781 rnj rnj rnj-2 rnj-2 uvrC uvrC rnz rnz recJ recJ PECL_875 PECL_875
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
chpBmRNA interferase ChpB. (118 aa)
PECL_1827Metallo-beta-lactamase superfamily protein. (268 aa)
addAATP-dependent helicase/nuclease subunit A; ATP-dependent DNA helicase. (1233 aa)
addBATP-dependent helicase/nuclease subunit B; ATP-dependent DNA helicase. (1182 aa)
rnpARibonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (119 aa)
ndoAmRNA interferase EndoA; Toxic component of a type II toxin-antitoxin (TA) system. (121 aa)
PECL_288Phosphoesterase family protein. (272 aa)
dnaNDNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (379 aa)
PECL_377PIN domain protein. (370 aa)
PECL_382Ribonuclease BN-like family protein; Belongs to the UPF0761 family. (316 aa)
xthExodeoxyribonuclease III. (251 aa)
PECL_444RNase H family protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (269 aa)
mrnCRNase3 domain protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. (137 aa)
holBDNA polymerase III, delta' subunit. (326 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (667 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (949 aa)
rnrRibonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (787 aa)
PECL_567Exonuclease, DNA polymerase III, epsilon subunit family protein. (178 aa)
PECL_595HNH endonuclease family protein, phage-related protein. (125 aa)
dnaEDNA polymerase III, alpha subunit. (1109 aa)
PECL_676endonuclease/Exonuclease/phosphatase family protein. (358 aa)
rnyRibonuclease Y; Endoribonuclease that initiates mRNA decay. (519 aa)
PECL_721DHH family protein. (317 aa)
yrrKPutative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (146 aa)
mutS2mutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (786 aa)
PECL_92Hydrolase, TatD family protein. (260 aa)
polCDNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1438 aa)
rnhBRibonuclease HII family protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (252 aa)
rnmVRibonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. (189 aa)
ybeYHypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (156 aa)
nfoPutative endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (288 aa)
PECL_1682DEAD/DEAH box helicase family protein. (784 aa)
PECL_1657parB-like partition s domain protein; Belongs to the ParB family. (283 aa)
PECL_1614Ribonuclease BN-like family protein; Belongs to the UPF0761 family. (291 aa)
PECL_1536pemK-like family protein. (111 aa)
rny-2Hypothetical protein; Endoribonuclease that initiates mRNA decay. (512 aa)
PECL_1335Hypothetical protein. (217 aa)
PECL_1175DNA/RNA non-specific endonuclease family protein. (268 aa)
PECL_1157Calcineurin-like phosphoesterase family protein. (406 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (885 aa)
PECL_1114HD domain protein. (167 aa)
xseAExodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (448 aa)
xseBExodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (77 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (232 aa)
dinGExonuclease, DNA polymerase III, epsilon subunit family domain protein; 3'-5' exonuclease. (926 aa)
PECL_102Hypothetical protein. (86 aa)
recURecombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. (197 aa)
PECL_781Metallo-beta-lactamase family protein. (246 aa)
rnjConserved hypothetical family protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (558 aa)
rnj-2RNA-metabolising metallo-beta-lactamase family protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (569 aa)
uvrCExcinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (617 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (309 aa)
recJsingle-stranded-DNA-specific exonuclease RecJ. (772 aa)
PECL_875Hypothetical protein. (424 aa)
Your Current Organism:
Pediococcus claussenii
NCBI taxonomy Id: 701521
Other names: P. claussenii ATCC BAA-344, Pediococcus claussenii ATCC BAA-344, Pediococcus claussenii ATCC str. BAA-344, Pediococcus claussenii ATCC strain BAA-344
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