(30 nodes) Lagging Strand Synthesis, and Epsilon DNA polymerase complex network (Ostreococcus tauri)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	A0A090LXS2	Unnamed product. (465 aa)
	A0A090M1K2	Checkpoint protein Hus1/Mec3. (315 aa)
	A0A090M3J2	Transcription factor CBF/NF-Y/archaeal histone. (148 aa)
	A0A090M5D6	Rad9. (407 aa)
	A0A090M5H5	P-loop containing nucleoside triphosphate hydrolase. (927 aa)
	A0A090M5P7	DNA primase large subunit, eukaryotic/archaeal. (511 aa)
	A0A090M6Q2	P-loop containing nucleoside triphosphate hydrolase. (611 aa)
	A0A090M7S5	DNA polymerase. (1175 aa)
	A0A090M9A7	DNA polymerase delta, subunit 4. (116 aa)
	A0A090M9A8	DNA ligase. (778 aa)
	A0A090N3B1	P-loop containing nucleoside triphosphate hydrolase. (358 aa)
	A0A090N3J5	P-loop containing nucleoside triphosphate hydrolase. (931 aa)
	A0A090N3N1	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	A0A090N4U1	DNA primase large subunit, eukaryotic/archaeal. (517 aa)
	A0A090N4Y0	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (552 aa)
	A0A096P8Y1	P-loop containing nucleoside triphosphate hydrolase. (888 aa)
	A0A096PAL4	Sister chromatid cohesion protein Dcc1. (407 aa)
	A0A096PAV9	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (808 aa)
	A0A096PBR9	NAD-dependent DNA ligase, N-terminal. (832 aa)
	Q00WX0_OSTTA	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (452 aa)
	Q00X67_OSTTA	Replication protein A, C-terminal. (262 aa)
	Q00XQ6_OSTTA	P-loop containing nucleoside triphosphate hydrolase. (354 aa)
	Q00YE0_OSTTA	DNA polymerase alpha/epsilon, subunit B. (453 aa)
	Q00YV3_OSTTA	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2339 aa)
	Q00Z03_OSTTA	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (650 aa)
	Q012B7_OSTTA	P-loop containing nucleoside triphosphate hydrolase. (342 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (389 aa)
	Q013X2_OSTTA	DNA polymerase. (1530 aa)
	Q01F45_OSTTA	P-loop containing nucleoside triphosphate hydrolase. (341 aa)
	Q01F52_OSTTA	P-loop containing nucleoside triphosphate hydrolase. (553 aa)

Your Current Organism:

Ostreococcus tauri

NCBI taxonomy Id: 70448
Other names: O. tauri

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A090LXS2	A0A090M1K2	A0A090LXS2	A0A090M1K2	Unnamed product.	Checkpoint protein Hus1/Mec3.	0.644
A0A090LXS2	A0A090M3J2	A0A090LXS2	A0A090M3J2	Unnamed product.	Transcription factor CBF/NF-Y/archaeal histone.	0.627
A0A090LXS2	A0A090M5D6	A0A090LXS2	A0A090M5D6	Unnamed product.	Rad9.	0.642
A0A090LXS2	A0A090M5H5	A0A090LXS2	A0A090M5H5	Unnamed product.	P-loop containing nucleoside triphosphate hydrolase.	0.626
A0A090LXS2	A0A090M5P7	A0A090LXS2	A0A090M5P7	Unnamed product.	DNA primase large subunit, eukaryotic/archaeal.	0.747
A0A090LXS2	A0A090M6Q2	A0A090LXS2	A0A090M6Q2	Unnamed product.	P-loop containing nucleoside triphosphate hydrolase.	0.702
A0A090LXS2	A0A090M7S5	A0A090LXS2	A0A090M7S5	Unnamed product.	DNA polymerase.	0.687
A0A090LXS2	A0A090M9A8	A0A090LXS2	A0A090M9A8	Unnamed product.	DNA ligase.	0.715
A0A090LXS2	A0A090N3B1	A0A090LXS2	A0A090N3B1	Unnamed product.	P-loop containing nucleoside triphosphate hydrolase.	0.777
A0A090LXS2	A0A090N3J5	A0A090LXS2	A0A090N3J5	Unnamed product.	P-loop containing nucleoside triphosphate hydrolase.	0.493
A0A090LXS2	A0A090N3N1	A0A090LXS2	A0A090N3N1	Unnamed product.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.882
A0A090LXS2	A0A090N4U1	A0A090LXS2	A0A090N4U1	Unnamed product.	DNA primase large subunit, eukaryotic/archaeal.	0.747
A0A090LXS2	A0A090N4Y0	A0A090LXS2	A0A090N4Y0	Unnamed product.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.720
A0A090LXS2	A0A096PAL4	A0A090LXS2	A0A096PAL4	Unnamed product.	Sister chromatid cohesion protein Dcc1.	0.440
A0A090LXS2	A0A096PAV9	A0A090LXS2	A0A096PAV9	Unnamed product.	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses.	0.866
A0A090LXS2	A0A096PBR9	A0A090LXS2	A0A096PBR9	Unnamed product.	NAD-dependent DNA ligase, N-terminal.	0.493
A0A090LXS2	FEN1	A0A090LXS2	Q013G9	Unnamed product.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.744
A0A090LXS2	Q00WX0_OSTTA	A0A090LXS2	Q00WX0	Unnamed product.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.863
A0A090LXS2	Q00XQ6_OSTTA	A0A090LXS2	Q00XQ6	Unnamed product.	P-loop containing nucleoside triphosphate hydrolase.	0.781
A0A090LXS2	Q00YE0_OSTTA	A0A090LXS2	Q00YE0	Unnamed product.	DNA polymerase alpha/epsilon, subunit B.	0.660