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| | PH1374 | 315aa long hypothetical proliferating-cell nucleolar protein p120; Similar to owl:A48998 percent identity: 42.908 in 289aa; PIR:B64303 percent identity: 45.982 in 234aa; Swiss_Prot:P46087 percent identity: 42.553 in 289aa. motif=ATP/GTP-binding site motif A (P-loop); NOL1/NOP2/sun family signature; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (315 aa) |
| | PH1379 | 229aa long hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (229 aa) |
| | PH1381 | 138aa long hypothetical translation initiation factor eIF-5a; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (138 aa) |
| | PH1397 | 342aa long hypothetical deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. (342 aa) |
| | PH1401 | 203aa long hypothetical protein; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. (203 aa) |
| | PH1416 | 330aa long hypothetical protein; Similar to PIR:C64410 percent identity: 45.625 in 343aa; PIR:D64494 percent identity: 40.097 in 212aa. (330 aa) |
| | PH1463 | 438aa long hypothetical L-asparaginase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (438 aa) |
| | PH1464 | 635aa long hypothetical protein; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (635 aa) |
| | PH1465 | 650aa long hypothetical protein; Similar to PIR:H64502 percent identity: 40.689 in 678aa. (650 aa) |
| | PH1478 | 629aa long hypothetical arginyl-tRNA synthetase; Similar to PIR:F64329 percent identity: 40.975 in 639aa; Swiss_Prot:P43832 percent identity: 40.000 in 192aa. motif=aminoacyl-transfer RNA synthetases class-I signature. (629 aa) |
| | PH1481 | 120aa long hypothetical protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (120 aa) |
| | PH1482 | 300aa long hypothetical transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (300 aa) |
| | PH1483 | 102aa long hypothetical 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | PH1484 | 428aa long hypothetical elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (428 aa) |
| | PHS040 | 71aa long hypothetical 50S ribosomal protein S28; Similar to Swiss_Prot:P54065 percent identity: 64.179 in 67aa; Swiss_Prot:P33286 percent identity: 62.069 in 60aa; Swiss_Prot:P33285 percent identity: 62.069 in 60aa; Belongs to the eukaryotic ribosomal protein eS28 family. (71 aa) |
| | PH1496 | 124aa long hypothetical 50S ribosomal protein L7; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, box H/ACA, box C/D and box C'/D' sRNAs (By similarity). When added to reconstituted ribonuclease P (RNase P) it increases the optimum temperature to that of the partially purified enzyme and causes a 5-fold increase in apparent Vmax. Binds the RNase P catalytic RNA. (124 aa) |
| | PHS041 | 62aa long hypothetical 50S ribosomal proteinL37; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (62 aa) |
| | PH1529 | 369aa long hypothetical phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity). (369 aa) |
| | PH1536 | 142aa long hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. (142 aa) |
| | PH1537 | 312aa long hypothetical nucleolar protein; Similar to owl:D908275 percent identity: 44.298 in 236aa; owl:A48998 percent identity: 38.376 in 277aa; Swiss_Prot:P40991 percent identity: 39.483 in 278aa; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (312 aa) |
| | PH1538 | 409aa long hypothetical protein; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (409 aa) |
| | PH1539 | 121aa long hypothetical protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. (121 aa) |
| | PH1541 | 218aa long hypothetical 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center (By similarity); Belongs to the universal ribosomal protein uS7 family. (218 aa) |
| | PH1542 | 150aa long hypothetical 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (150 aa) |
| | PH1543 | 145aa long hypothetical transcription termination-antitermination factor nusA; Participates in transcription termination. Belongs to the NusA family. (145 aa) |
| | PHS043 | 99aa long hypothetical 50S ribosomal protein L30; Similar to Swiss_Prot:P29160 percent identity: 70.833 in 96aa; Swiss_Prot:P54061 percent identity: 50.505 in 99aa; Swiss_Prot:P11522 percent identity: 50.538 in 93aa. motif=ribosomal protein L30e signatures; Belongs to the eukaryotic ribosomal protein eL30 family. (99 aa) |
| | PH1544 | 397aa long hypothetical DNA-directed RNA polymerase subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (397 aa) |
| | PH1545 | 907aa long hypothetical DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (907 aa) |
| | PH1546 | 1117aa long hypothetical DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1117 aa) |
| | PHS044 | 82aa long hypothetical DNA-directed RNA polymerase subunit Hprotein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (82 aa) |
| | PH1568 | 116aa long hypothetical translation initiation factor eIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). (116 aa) |
| | PH1581 | 139aa long hypothetical protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (139 aa) |
| | PH1584 | 417aa long hypothetical eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (417 aa) |
| | PH1601 | 120aa long hypothetical protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Binds RNase P RNA. (120 aa) |
| | PH1602 | 871aa long hypothetical protein; GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends. (871 aa) |
| | PH1614 | 570aa long hypothetical glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). (570 aa) |
| | PH1629 | 205aa long hypothetical 30S ribosomal protein S2; Similar to Swiss_Prot:P54109 percent identity: 66.667 in 192aa; owl:SS56KBFR54 percent identity: 57.071 in 198aa; Swiss_Prot:P29202 percent identity: 57.627 in 177aa. motif=ribosomal protein S2 signatures; Belongs to the universal ribosomal protein uS2 family. (205 aa) |
| | PH1632 | 119aa long hypothetical DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (119 aa) |
| | PH1633 | 135aa long hypothetical 30S ribosomal protein S9; Similar to Swiss_Prot:P54024 percent identity: 64.925 in 134aa; Swiss_Prot:P05763 percent identity: 51.908 in 133aa; owl:SS56KBFR53 percent identity: 49.242 in 134aa. motif=ribosomal protein S9 signature; Belongs to the universal ribosomal protein uS9 family. (135 aa) |
| | PH1634 | 142aa long hypothetical 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa) |
| | PH1636 | 120aa long hypothetical 50S ribosomal protein L18; Similar to Swiss_Prot:P54022 percent identity: 66.949 in 118aa; Swiss_Prot:P12733 percent identity: 50.000 in 113aa; Swiss_Prot:P39474 percent identity: 48.000 in 104aa; Belongs to the eukaryotic ribosomal protein eL18 family. (120 aa) |
| | PH1637 | 261aa long hypothetical DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. (261 aa) |
| | PH1638 | 137aa long hypothetical 30S ribosomal protein S11; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (137 aa) |
| | PH1640 | 180aa long hypothetical 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (180 aa) |
| | PH1641 | 148aa long hypothetical 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (148 aa) |
| | PH1644 | 334aa long hypothetical centromere/microtubule binding protein; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (334 aa) |
| | PH1680 | 320aa long hypothetical protein; Similar to PIR:E64444 percent identity: 40.203 in 305aa; PIR:E64484 percent identity: 37.500 in 311aa; owl:S71668 percent identity: 37.008 in 260aa. (320 aa) |
| | PH1686 | 570aa long hypothetical glutaminyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (570 aa) |
| | PHS046 | 70aa long hypothetical archaeal histon; Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation (By similarity). (70 aa) |
| | PH1705 | 342aa long hypothetical protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe); Belongs to the TYW1 family. (342 aa) |
| | PH1706 | 411aa long hypothetical translation initiation factor eIF-2 gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (411 aa) |
| | PH1755 | 150aa long hypothetical 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (150 aa) |
| | PH1756 | 155aa long hypothetical 50S ribosomal protein L30; Similar to Swiss_Prot:P54046 percent identity: 66.667 in 152aa; Swiss_Prot:P14035 percent identity: 54.000 in 152aa; GENPEPT:Y07778 percent identity: 43.709 in 153aa. motif=ribosomal protein L30 signature. (155 aa) |
| | PH1757 | 236aa long hypothetical 30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy. (236 aa) |
| | PH1758 | 206aa long hypothetical 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (206 aa) |
| | PH1759 | 150aa long hypothetical 50S ribosomal protein L19; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (150 aa) |
| | PH1761 | 130aa long hypothetical 50S ribosomal protein L32; Similar to Swiss_Prot:P54010 percent identity: 61.864 in 120aa; Swiss_Prot:P14549 percent identity: 47.934 in 123aa; GENPEPT:Y07778 percent identity: 43.119 in 111aa; Belongs to the eukaryotic ribosomal protein eL32 family. (130 aa) |
| | PH1763 | 187aa long hypothetical 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (187 aa) |
| | PH1764 | 130aa long hypothetical 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | PHS047 | 56aa long hypothetical 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles. (56 aa) |
| | PH1765 | 188aa long hypothetical 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (188 aa) |
| | PH1766 | 243aa long hypothetical 30S ribosomal protein S4; Similar to Swiss_Prot:P54039 percent identity: 52.720 in 247aa; Swiss_Prot:P14023 percent identity: 47.280 in 247aa; GENPEPT:Y07778 percent identity: 36.752 in 238aa. motif=ribosomal protein S4e signature; Belongs to the eukaryotic ribosomal protein eS4 family. (243 aa) |
| | PH1767 | 124aa long hypothetical 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (124 aa) |
| | PH1768 | 144aa long hypothetical 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (144 aa) |
| | PH1770 | 116aa long hypothetical 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (116 aa) |
| | PH1771 | 127aa long hypothetical protein; Part of ribonuclease P (RNase P), a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Binds RNase P RNA. (127 aa) |
| | PHS048 | 60aa long hypothetical 50S ribosomal protein L29; Similar to Swiss_Prot:P54035 percent identity: 45.455 in 55aa; Swiss_Prot:P22665 percent identity: 33.962 in 53aa; Swiss_Prot:P10971 percent identity: 35.849 in 53aa. motif=ribosomal protein L29 signature; Belongs to the universal ribosomal protein uL29 family. (60 aa) |
| | PH1772 | 210aa long hypothetical 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (210 aa) |
| | PH1773 | 155aa long hypothetical 50S ribosomal protein L22; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (155 aa) |
| | PH1774 | 132aa long hypothetical 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (132 aa) |
| | PH1775 | 239aa long hypothetical 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (239 aa) |
| | PHS049 | 86aa long hypothetical 50S ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa) |
| | PH1776 | 255aa long hypothetical 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (255 aa) |
| | PH1777 | 362aa long hypothetical 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (362 aa) |
| | PH1803 | 189aa long hypothetical protein; Motif=prenyl group binding site (CAAX box). (189 aa) |
| | PH1812 | 424aa long hypothetical protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (424 aa) |
| | PH1823 | 290aa long hypothetical dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (290 aa) |
| | PH1829 | 381aa long hypothetical N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (381 aa) |
| | PHS052 | 87aa long hypothetical 50S ribosomal protein L35; Similar to Swiss_Prot:P20299 percent identity: 91.954 in 87aa; Swiss_Prot:P41056 percent identity: 38.095 in 92aa; Swiss_Prot:P05744 percent identity: 36.905 in 92aa. motif=ribosomal protein L35Ae signature; Belongs to the eukaryotic ribosomal protein eL33 family. (87 aa) |
| | PH1839 | 221aa long hypothetical protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family. (221 aa) |
| | PH1858 | 253aa long hypothetical protein; Similar to PIR:F64316 percent identity: 47.059 in 269aa; owl:MTCY26113 percent identity: 36.145 in 254aa; owl:S72844 percent identity: 35.887 in 259aa. (253 aa) |
| | PH1875 | 432aa long hypothetical protein; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. (432 aa) |
| | PH1877 | 212aa long hypothetical protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Not absolutely essential for activity in vitro, however it strongly stimulates activity. Binds RNase P RNA. Belongs to the eukaryotic/archaeal RNase P protein component 3 family. (212 aa) |
| | PH1887 | 206aa long hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. (206 aa) |
| | PH1899 | 735aa long hypothetical elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation facto [...] (735 aa) |
| | PH1900 | 334aa long hypothetical protein; Probably involved in the biogenesis of the ribosome. (224 aa) |
| | PHS056 | 77aa long hypothetical DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. (77 aa) |
| | PHS057 | 86aa long hypothetical 50S ribosomal protein L37; Binds to the 23S rRNA. (86 aa) |
| | PH1908 | 188aa long hypothetical DNA-directed RNA polymerase subunit E; Similar to PIR:E64349 percent identity: 53.804 in 184aa; Swiss_Prot:P39466 percent identity: 47.059 in 172aa. (188 aa) |
| | PH1921 | 301aa long hypothetical tryptophanyl-tRNA synthetase; Similar to owl:S51901 percent identity: 49.296 in 298aa; Swiss_Prot:Q09692 percent identity: 48.352 in 286aa; Swiss_Prot:P23381 percent identity: 46.831 in 301aa; Belongs to the class-I aminoacyl-tRNA synthetase family. (301 aa) |
| | PH1940 | 109aa long hypothetical 50S ribosomal protein L44; Binds to the 23S rRNA. (109 aa) |
| | PH1947 | 1235aa long hypothetical DNA-directed DNA polymerase; Similar to PIR:S68593 percent identity: 75.831 in 1312aa; Swiss_Prot:P30317 percent identity: 67.133 in 1082aa; owl:PYWKODPOL percent identity: 75.792 in 1671aa. motif=DNA polymerase family B signature; protein splicing signature; Belongs to the DNA polymerase type-B family. (1235 aa) |
| | PH1969 | 404aa long hypothetical alanyl-tRNA synthetase; Functions in trans to edit the amino acid moiety from mischarged charged tRNA(Ala). (404 aa) |
| | PH1975 | 964aa long hypothetical H(+)-transporting ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit; Belongs to the ATPase alpha/beta chains family. (964 aa) |
| | PH1987 | 324aa long hypothetical O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. (324 aa) |
| | PH1991 | 389aa long hypothetical nucleolar protein; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in several tRNAs. This modification appears to slightly promote the thermal stability of P.horikoshii tRNAs, but does not affect their amino acid accepting activity. Four elements in the acceptor stems of tRNAs are essential for substrate recognition by this enzyme: the target site C72, the 3'-CCA terminus, U73 or G73, and the second base pair C2:G71. (389 aa) |
| | PH1998 | 111aa long hypothetical 50S ribosomal protein L12; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. The stalk complex of P.horikoshii binds to E.coli large subunits and confers on them the ability to interact with eukaryotic elongation factors. Each succesive L12 dimer bound along the P0 spine increases the GTPase activity of elongation factors and increases translation by reconsituted ribosomes. (111 aa) |
| | PH1999 | 342aa long hypothetical acidic ribosomal protein P0 (L10E); Forms the large subunit's ribosomal stalk, playing a central role in the interaction of the ribosome with elongation factors; the stalk complex of P.horikoshii binds to E.coli large subunits and confers on them the ability to interact with eukaryotic elongation factors. Each succesive L12 dimer bound along the P0 spine increases the GTPase activity of elongation factors and increases translation by reconsituted ribosomes, although the first site is the most stimulatory; Belongs to the universal ribosomal protein uL10 family. (342 aa) |
| | PH1137 | 407aa long hypothetical RNA methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (407 aa) |
| | PH1151 | 307aa long hypothetical sulfatase; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (307 aa) |
| | PH1242 | 262aa long hypothetical pseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (262 aa) |
| | PH1259 | 412aa long hypothetical protein; Catalyzes the formation of 5-methyl-uridine at position equivalent to 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (412 aa) |
| | PHS035 | 94aa long hypothetical 50S ribosomal protein L34; Similar to Swiss_Prot:P54053 percent identity: 63.095 in 85aa; GENPEPT:Y13049 percent identity: 43.750 in 84aa; Swiss_Prot:P45842 percent identity: 36.986 in 74aa; Belongs to the eukaryotic ribosomal protein eL34 family. (94 aa) |
| | PHS037 | 51aa long hypothetical 50S ribosomal protein L40; Similar to Swiss_Prot:P54058 percent identity: 71.111 in 45aa; Belongs to the eukaryotic ribosomal protein eL40 family. (51 aa) |
| | PH1313 | 307aa long hypothetical protein; Similar to PIR:C64416 percent identity: 39.381 in 231aa. (307 aa) |
| | PH1325 | 150aa long hypothetical 30S ribosomal protein S19; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (150 aa) |
| | PHS032 | 97aa long hypothetical 50S ribosomal protein L21; Similar to Swiss_Prot:P54013 percent identity: 67.368 in 95aa; Swiss_Prot:P12734 percent identity: 51.163 in 86aa; GENPEPT:F20014 percent identity: 37.500 in 72aa; Belongs to the eukaryotic ribosomal protein eL21 family. (97 aa) |
| | PH1127 | 121aa long hypothetical protein; Similar to PIR:G64304 percent identity:51.887 in 118aa. (121 aa) |
| | PH1116 | 582aa long hypothetical protein; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs. (582 aa) |
| | PH1110 | 1352aa long hypothetical ATP-dependent helicase LHR; Similar to PIR:G64336 percent identity:59.481 in 515aa; owl:SS56KBFR9 percent identity:49.126 in 526aa; owl:MTCY7135 percent identity:40.068 in 300aa. (1352 aa) |
| | PH1103 | 127aa long hypothetical 30S ribosomal protein S8; Similar to Swiss_Prot:P54055 percent identity: 62.992 in 129aa; Swiss_Prot:P49402 percent identity: 49.167 in 122aa. (127 aa) |
| | PH1095 | 1044aa long hypothetical translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity). (1044 aa) |
| | PH1069 | 200aa long hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. (200 aa) |
| | PH1065 | 1066aa long hypothetical isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1066 aa) |
| | PH1020 | 438aa long hypothetical aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). (438 aa) |
| | PH1011 | 375aa long hypothetical tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. (375 aa) |
| | PH1009 | 191aa long hypothetical TATA-binding protein (transcription initiation factor TFIID); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity). (191 aa) |
| | PH1006 | 480aa long hypothetical prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (480 aa) |
| | PH0993 | 723aa long hypothetical methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (723 aa) |
| | PH0978 | 238aa long hypothetical 50S ribosomal protein L15; Similar to Swiss_Prot:P54060 percent identity: 70.103 in 194aa; Swiss_Prot:P49403 percent identity: 60.638 in 188aa; owl:ATFCA635 percent identity: 51.064 in 190aa. motif=ribosomal protein L15e signature; tubulin-beta mRNA autoregulation signal; Belongs to the eukaryotic ribosomal protein eL15 family. (238 aa) |
| | PH0965 | 967aa long hypothetical leucyl-tRNA synthetase; Similar to PIR:A64379 percent identity: 53.987 in 980aa; owl:F21M12 percent identity: 36.017 in 737aa; Swiss_Prot:Q09996 percent identity: 34.910 in 766aa. motif=aminoacyl-transfer RNA synthetases class-I signature. (967 aa) |
| | PH0962 | 407aa long hypothetical protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (407 aa) |
| | PH0961 | 275aa long hypothetical translation initiation factor eIF-2 alpha chain; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family. (275 aa) |
| | PH0864 | 208aa long hypothetical transcription initiation factor IIB; Similar to Swiss_Prot:P29095 percent identity: 55.556 in 198aa; PIR:S34116 percent identity: 55.556 in 198aa; Swiss_Prot:P50387 percent identity: 50.000 in 198aa. motif=transcription factor TFIIB repeat signature. (208 aa) |
| | PH0851 | 450aa long hypothetical fmu protein; Similar to PIR:S74920 percent identity: 34.459 in 301aa; Swiss_Prot:P36929 percent identity: 32.117 in 277aa; Swiss_Prot:P45679 percent identity: 29.966 in 301aa. motif=ATP/GTP-binding site motif A (P-loop); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (450 aa) |
| | PH0800 | 1624aa long hypothetical reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity); In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily. (1624 aa) |
| | PH0795 | 105aa long hypothetical protein; Similar to PIR:B64411 percent identity:43.038 in 80aa; Belongs to the UPF0148 family. (105 aa) |
| | PH0793 | 278aa long hypothetical protein; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). (278 aa) |
| | PH0788 | 816aa long hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (816 aa) |
| | PH0763 | 167aa long hypothetical protein; Putative transcriptional regulator. (167 aa) |
| | PH0744 | 124aa long hypothetical protein. (124 aa) |
| | PH0730 | 214aa long hypothetical protein. (214 aa) |
| | PH0711 | 419aa long hypothetical protein. (419 aa) |
| | PH0710 | 460aa long hypothetical seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (460 aa) |
| | PH0706 | 185aa long hypothetical protein. (185 aa) |
| | PH0699 | 625aa long hypothetical threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr); Belongs to the class-II aminoacyl-tRNA synthetase family. (625 aa) |
| | PH0664 | 110aa long hypothetical transcription-associated protein; Similar to PIR:A55263 percent identity: 65.138 in 110aa; PIR:C64443 percent identity: 47.222 in 110aa. motif=TFIIS zinc ribbon domain signature; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (110 aa) |
| | PH0658 | 499aa long hypothetical phenylalanyl-tRNA synthetase subunit alpha chain; Similar to PIR:G64360 percent identity: 41.837 in 411aa; owl:SS56KBFR21 percent identity: 38.829 in 495aa; owl:CH19HHR234 percent identity: 42.907 in 297aa. motif=aminoacyl-transfer RNA synthetases class-II signatures; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (499 aa) |
| | PH0657 | 556aa long hypothetical phenylalanyl-tRNA synthetase subunit beta chain; Similar to PIR:C64438 percent identity:44.751 in 550aa; owl:BBU829781 percent identity:34.120 in 564aa; OWL:SS56KBFR20 percent identity:36.420 in 501aa. (556 aa) |
| | PH0650 | 1136aa long hypothetical protein; Similar to PIR:E64397 percent identity: 49.580 in 363aa; owl:CLU77780 percent identity: 50.775 in 264aa; PIR:D64412 percent identity: 42.979 in 242aa. motif=ATP/GTP-binding site motif A (P-loop); tubulin subunits alpha, beta, and gamma signature. (1136 aa) |
| | PH0644 | 364aa long hypothetical protein; Similar to PIR:F64354 percent identity: 42.754 in 317aa. motif=uncharacterized protein family UPF0020 signature. (364 aa) |
| | PH0636 | 476aa long hypothetical cysteinyl-tRNA synthetase; Similar to Swiss_Prot:Q06752 percent identity: 48.707 in 473aa; Swiss_Prot:P43816 percent identity: 50.000 in 472aa; Swiss_Prot:P21888 percent identity: 48.904 in 474aa. (476 aa) |
| | PH0633 | 181aa long hypothetical ubiquinol-cytochrome c reductase complex subunit VI; Similar to PIR:G64367 percent identity: 54.717 in 159aa; owl:EGHUMSIM percent identity: 45.513 in 159aa; owl:AF013804 percent identity: 42.675 in 160aa; Belongs to the universal ribosomal protein uL16 family. (181 aa) |
| | PH0619 | 197aa long hypothetical protein; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexe [...] (197 aa) |
| | PH0615 | 125aa long hypothetical 30S ribosomal protein S6E; Similar to Swiss_Prot:P54067 percent identity: 64.545 in 124aa. motif=ribosomal protein S6e signature; Belongs to the eukaryotic ribosomal protein eS6 family. (125 aa) |
| | PH0606 | 1108aa long hypothetical cell division control protein; Similar to Swiss_Prot:P30665 percent identity:41.538 in 331aa. motif=ATP/GTP-binding site motif A (P-loop); protein splicing signature; Belongs to the MCM family. (1108 aa) |
| | PH0605 | 140aa long hypothetical translation initiation factor eIF-2 beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-beta/eIF-5 family. (140 aa) |
| | PH0590 | 154aa long hypothetical signal peptidase subunit; Similar to Swiss_Prot:P13679 percent identity:34.328 in 138aa; Swiss_Prot:P21378 percent identity:35.507 in 142aa. (154 aa) |
| | PH0563 | 330aa long hypothetical protein. (330 aa) |
| | PH0528 | 227aa long hypothetical protein; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (227 aa) |
| | PHS021 | 77aa long hypothetical 50S ribosomal protein LX; Similar to Swiss_Prot:P54052 percent identity: 48.571 in 71aa; Swiss_Prot:P38613 percent identity: 45.455 in 55aa; Swiss_Prot:P14125 percent identity: 40.385 in 52aa. (77 aa) |
| | PH0461 | 206aa long hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs. Belongs to the aTrm56 family. (206 aa) |
| | PH0452 | 1127aa long hypothetical ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Degrades polypeptides processively (By similarity); Belongs to the peptidase S16 family. Archaeal LonB subfamily. (1127 aa) |
| | PH0445 | 219aa long hypothetical protein; Similar to PIR:A64441 percent identity: 42.458 in 187aa. motif=protein kinases signatures and profile. (219 aa) |
| | PH0440 | 276aa long hypothetical translation initiation factor eIF-2B; Catalyzes the exchange of initiation factor 2-bound GDP for GTP; Belongs to the eIF-2B alpha/beta/delta subunits family. (276 aa) |
| | PH0435 | 340aa long hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (340 aa) |
| | PH0363 | 1291aa long hypothetical ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1291 aa) |
| | PH0338 | 329aa long hypothetical protein; Similar to PIR:F64388 percent identity:45.283 in 168aa; Swiss_Prot:P05409 percent identity:39.423 in 111aa. motif=N-6 Adenine-specific DNA methylases signature. (329 aa) |
| | PH0314 | 896aa long hypothetical valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (896 aa) |
| | PH0309 | 277aa long hypothetical protein; Similar to PIR:F64349 percent identity: 52.672 in 272aa. (277 aa) |
| | PH0300 | 310aa long hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2- thiouridine (m(5)s(2)U or s(2)T). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (By similarity). Can use free sulfide as sulfur source in vitro, which may be also the sulfur source in vivo ; Belongs to the TtcA family. TtuA subfamily. (310 aa) |
| | PH0297 | 915aa long hypothetical alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Edits incorrectly charged Ser-tRNA(Ala). Incorrectly charged amino acids occur because the of inherent physicochemical limitations on discrimination between closely related amino acids (Gly and Ser) in the charging step. Belongs to the class-II aminoacyl-tRNA synthetase family. (915 aa) |
| | PH0296 | 172aa long hypothetical acetyltransferase; Similar to PIR:A64491 percent identity: 42.029 in 140aa; owl:SS56KBFR39 percent identity: 36.620 in 142aa. (172 aa) |
| | PH0295 | 170aa long hypothetical protein; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (170 aa) |
| | PH0290 | 431aa long hypothetical histidyl-tRNA synthetase; Similar to PIR:G64424 percent identity: 45.854 in 425aa; owl:HPAE0006251 percent identity: 33.577 in 418aa; Swiss_Prot:P46220 percent identity: 46.617 in 133aa; Belongs to the class-II aminoacyl-tRNA synthetase family. (431 aa) |
| | PH0285 | 112aa long hypothetical methionyl-tRNA synthetase; Similar to PIR:F64457 percent identity:45.370 in 108aa; Swiss_Prot:P23395 percent identity:48.485 in 100aa. (112 aa) |
| | PH0270 | 294aa long hypothetical asparaginyl-tRNA synthetase; Similar to owl:STOMPS3GN percent identity:32.500 in 81aa; Swiss_Prot:P54263 percent identity:39.130 in 93aa. (294 aa) |
| | PH0263 | 529aa long hypothetical DNA repair protein; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity). (529 aa) |
| | PH0261 | 206aa long hypothetical protein; Similar to PIR:E64422 percent identity:36.145 in 174aa. (206 aa) |
| | PH0241 | 434aa long hypothetical asparaginyl-tRNA synthetase; Similar to Swiss_Prot:P39772 percent identity: 47.242 in 420aa; Swiss_Prot:P54262 percent identity: 44.712 in 419aa; Swiss_Prot:P54263 percent identity: 45.455 in 439aa. motif=aminoacyl-transfer RNA synthetases class-II signatures. (434 aa) |
| | PH0224 | 523aa long hypothetical lysyl-tRNA synthetase; Similar to PIR:C64367 percent identity: 40.971 in 535aa. motif=aminoacyl-transfer RNA synthetases class-I signature. (523 aa) |
| | PH0197 | 361aa long hypothetical protein; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA. (361 aa) |
| | PH0160 | 177aa long hypothetical protein; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase (By similarity). (177 aa) |
| | PH0135 | 570aa long hypothetical protein; Similar to PIR:E64427 percent identity:29.295 in 479aa. (570 aa) |
| | PH0121 | 1434aa long hypothetical protein; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity). (1434 aa) |
| | PH0117 | 472aa long hypothetical protein; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. (472 aa) |
| | PH0115 | 296aa long hypothetical protein; Similar to PIR:C64410 percent identity:37.021 in 246aa. (296 aa) |
| | PH0112 | 855aa long hypothetical replication factor C subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (855 aa) |
| | PH0108 | 216aa long hypothetical alanyl-tRNA synthetase; Functions in trans to edit the amino acid moiety from mischarged charged Gly-tRNA(Ala) and Ser-tRNA(Ala). Belongs to the class-II aminoacyl-tRNA synthetase family. Editing domain AlaX-M subfamily. (216 aa) |
| | PH0101 | 481aa long hypothetical protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (481 aa) |
| | PH0084 | 158aa long hypothetical protein. (158 aa) |
| | PH0080 | 355aa long hypothetical protein; Similar to PIR:E64352 percent identity: 62.281 in 346aa. (355 aa) |
| | PH0060 | 199aa long hypothetical 30S ribosomal protein S3a; Similar to Swiss_Prot:P54059 percent identity: 41.579 in 190aa; Belongs to the eukaryotic ribosomal protein eS1 family. (199 aa) |
| | PH0058 | 158aa long hypothetical 40S ribosomal protein S13; Similar to Swiss_Prot:P54012 percent identity: 70.667 in 157aa; Swiss_Prot:Q05761 percent identity: 50.000 in 157aa; Swiss_Prot:P49203 percent identity: 48.649 in 155aa. motif=ribosomal protein S15 signature. (158 aa) |
| | PH0052 | 227aa long hypothetical fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (227 aa) |
| | PH0043 | 200aa long hypothetical protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (200 aa) |
| | PH0002 | 155aa long hypothetical transcription termination-antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (155 aa) |
| | PH0001 | 164aa long hypothetical 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (164 aa) |
| | PH2000 | 219aa long hypothetical 50S ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (219 aa) |
