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ispB ispB ispH ispH dxr dxr dxs dxs ispA ispA idi idi ispE ispE ispG ispG ispF ispF ispD ispD crtE crtE crtX crtX crtY crtY crtI crtI crtB crtB crtZ crtZ
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ispBIspB; Octaprenyl-diphosphate synthase; Similar to Pantoea sp. At-9b, Polyprenyl synthetase (NCBI: ZP_05730881.1); COG: Coenzyme transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic. (323 aa)
ispHIspH; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. (316 aa)
dxrDxr; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP). (402 aa)
dxsDxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (633 aa)
ispAIspA; Geranyltranstransferase; Similar to Pantoea sp. At-9b, Polyprenyl synthetase (NCBI: ZP_05727464.1); COG: Coenzyme transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic; Belongs to the FPP/GGPP synthase family. (299 aa)
idiIdi; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (210 aa)
ispEIspE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. (285 aa)
ispGIspG; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (378 aa)
ispFIspF; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (160 aa)
ispDIspD; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (238 aa)
crtECrtE; Geranylgeranyl pyrophosphate synthetase; Similar to >sp|P21684.1|CRTE_PANAN RecName: Full=Geranylgeranyl pyrophosphate synthetase; Short=GGPP synthetase; AltName: Full=Farnesyltranstransferas,CRTE_PANAN RecName: Full=Geranylgeranyl pyrophosphate synthetase; Short=GGPP synthetase; AltName: Full=Farnesyltranstransferas(NCBI: P21684.1); COG: Coenzyme transport and metabolism; Subcellular localization as predicted by Psort 2.0: Cytoplasmic; Belongs to the FPP/GGPP synthase family. (311 aa)
crtXCrtX; Zeaxanthin glucosyl transferase; Similar to >sp|P21686.1|CRTX_PANAN RecName: Full=Zeaxanthin glucosyltransferas,CRTX_PANAN RecName: Full=Zeaxanthin glucosyltransferas(NCBI: P21686.1); COG: Carbohydrate transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown; Belongs to the UDP-glycosyltransferase family. (431 aa)
crtYCrtY; Lycopene cyclase; Similar to >sp|P21687.1|CRTY_PANAN RecName: Full=Lycopene cyclas,CRTY_PANAN RecName: Full=Lycopene cyclas(NCBI: P21687.1); COG: Secondary metabolites biosynthesis, transport and catabolism; Subcellular localization as predicted by Psort 2.0: Inner Membrane. (386 aa)
crtICrtI; Phytoene dehydrogenase; Similar to >sp|P21685.1|CRTI_PANAN RecName: Full=Phytoene dehydrogenase; AltName: Full=Phytoene desaturas,CRTI_PANAN RecName: Full=Phytoene dehydrogenase; AltName: Full=Phytoene desaturas(NCBI: P21685.1); COG: Secondary metabolites biosynthesis, transport and catabolism; Subcellular localization as predicted by Psort 2.0: Unknown. (492 aa)
crtBCrtB; Phytoene synthase; Similar to >sp|P21683.2|CRTB_PANAN RecName: Full=Phytoene synthas,CRTB_PANAN RecName: Full=Phytoene synthas(NCBI: P21683.2); COG: Lipid transport and metabolism; Subcellular localization as predicted by Psort 2.0: Unknown. (309 aa)
crtZCrtZ; Beta-carotene hydroxylase; Similar to >sp|P21688.1|CRTZ_PANAN RecName: Full=Beta-carotene hydroxylas,CRTZ_PANAN RecName: Full=Beta-carotene hydroxylas(NCBI: P21688.1); COG: Secondary metabolites biosynthesis, transport and catabolism; Subcellular localization as predicted by Psort 2.0: Inner Membrane. (175 aa)
Your Current Organism:
Pantoea ananatis
NCBI taxonomy Id: 706191
Other names: P. ananatis LMG 20103, Pantoea ananatis LMG 20103, Pantoea ananatis str. LMG 20103, Pantoea ananatis strain LMG 20103
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