(11 nodes) rRNA-binding network (Sulcia muelleri CARI)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rpsB	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (218 aa)
	rpsO	30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (84 aa)
	rpsG	30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (158 aa)
	rpsJ	30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
	rplD	50S ribosomal subunit protein L4; Forms part of the polypeptide exit tunnel. (208 aa)
	rpsS	30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (93 aa)
	rpsC	30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (225 aa)
	rpsQ	30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (86 aa)
	rpsH	30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (133 aa)
	rpsM	30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (126 aa)
	rpsK	30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (120 aa)

Your Current Organism:

Sulcia muelleri CARI

NCBI taxonomy Id: 706194
Other names: C. Sulcia muelleri CARI, Candidatus Sulcia muelleri CARI, Candidatus Sulcia muelleri str. CARI, Candidatus Sulcia muelleri strain CARI

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
rplD	rpsB	SMCARI_242	SMCARI_103	50S ribosomal subunit protein L4; Forms part of the polypeptide exit tunnel.	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.999
rplD	rpsC	SMCARI_242	SMCARI_247	50S ribosomal subunit protein L4; Forms part of the polypeptide exit tunnel.	30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.	0.999
rplD	rpsG	SMCARI_242	SMCARI_238	50S ribosomal subunit protein L4; Forms part of the polypeptide exit tunnel.	30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.999
rplD	rpsH	SMCARI_242	SMCARI_254	50S ribosomal subunit protein L4; Forms part of the polypeptide exit tunnel.	30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.	0.999
rplD	rpsJ	SMCARI_242	SMCARI_240	50S ribosomal subunit protein L4; Forms part of the polypeptide exit tunnel.	30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.999
rplD	rpsK	SMCARI_242	SMCARI_263	50S ribosomal subunit protein L4; Forms part of the polypeptide exit tunnel.	30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	0.999
rplD	rpsM	SMCARI_242	SMCARI_262	50S ribosomal subunit protein L4; Forms part of the polypeptide exit tunnel.	30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.	0.999
rplD	rpsO	SMCARI_242	SMCARI_234	50S ribosomal subunit protein L4; Forms part of the polypeptide exit tunnel.	30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.	0.999
rplD	rpsQ	SMCARI_242	SMCARI_249	50S ribosomal subunit protein L4; Forms part of the polypeptide exit tunnel.	30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.	0.999
rplD	rpsS	SMCARI_242	SMCARI_245	50S ribosomal subunit protein L4; Forms part of the polypeptide exit tunnel.	30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.	0.999
rpsB	rplD	SMCARI_103	SMCARI_242	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	50S ribosomal subunit protein L4; Forms part of the polypeptide exit tunnel.	0.999
rpsB	rpsC	SMCARI_103	SMCARI_247	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.	0.999
rpsB	rpsG	SMCARI_103	SMCARI_238	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.999
rpsB	rpsH	SMCARI_103	SMCARI_254	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.	0.999
rpsB	rpsJ	SMCARI_103	SMCARI_240	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.999
rpsB	rpsK	SMCARI_103	SMCARI_263	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	0.999
rpsB	rpsM	SMCARI_103	SMCARI_262	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.	0.999
rpsB	rpsO	SMCARI_103	SMCARI_234	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.	0.999
rpsB	rpsQ	SMCARI_103	SMCARI_249	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.	0.999
rpsB	rpsS	SMCARI_103	SMCARI_245	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.	0.999

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