STRINGSTRING
A0A139WCT9 A0A139WCT9 A0A139WF97 A0A139WF97 A0A139WFH4 A0A139WFH4 A0A139WK88 A0A139WK88 A0A139WM00 A0A139WM00 D2A2D3_TRICA D2A2D3_TRICA D2A2P4_TRICA D2A2P4_TRICA D2A5W4_TRICA D2A5W4_TRICA D6W806_TRICA D6W806_TRICA D6WBZ3_TRICA D6WBZ3_TRICA D6WDE8_TRICA D6WDE8_TRICA D6WF20_TRICA D6WF20_TRICA D6WFV5_TRICA D6WFV5_TRICA MCM7 MCM7 D6WK37_TRICA D6WK37_TRICA D6WMH9_TRICA D6WMH9_TRICA D6WNB7_TRICA D6WNB7_TRICA D6WQQ2_TRICA D6WQQ2_TRICA Fen1 Fen1 D6WSI2_TRICA D6WSI2_TRICA D6WSX8_TRICA D6WSX8_TRICA D6WVB2_TRICA D6WVB2_TRICA Rpa2 Rpa2 D6WXD7_TRICA D6WXD7_TRICA D6WXY2_TRICA D6WXY2_TRICA D6WZF7_TRICA D6WZF7_TRICA D6WZI9_TRICA D6WZI9_TRICA D6X0G8_TRICA D6X0G8_TRICA D6X269_TRICA D6X269_TRICA D6X3S8_TRICA D6X3S8_TRICA D6X470_TRICA D6X470_TRICA D6X4M6_TRICA D6X4M6_TRICA D7EHU8_TRICA D7EHU8_TRICA D7EIV8_TRICA D7EIV8_TRICA D7EJW6_TRICA D7EJW6_TRICA RfC40 RfC40
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A139WCT9Replication factor C subunit 2-like Protein. (331 aa)
A0A139WF97DNA helicase; Belongs to the MCM family. (570 aa)
A0A139WFH4DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (519 aa)
A0A139WK88DNA polymerase epsilon subunit 3-like Protein. (126 aa)
A0A139WM00Uncharacterized protein. (412 aa)
D2A2D3_TRICASingle-stranded DNA-binding protein, mitochondrial-like Protein. (149 aa)
D2A2P4_TRICAReplication factor C subunit 2-like Protein. (355 aa)
D2A5W4_TRICAReplication protein A 32 kDa subunit-like Protein. (227 aa)
D6W806_TRICARibonuclease H1-like Protein. (231 aa)
D6WBZ3_TRICADNA polymerase. (1050 aa)
D6WDE8_TRICADNA replication ATP-dependent helicase/nuclease DNA2-like Protein. (1211 aa)
D6WF20_TRICADNA ligase. (756 aa)
D6WFV5_TRICARibonuclease H2 subunit C-like Protein. (136 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
D6WK37_TRICADNA polymerase. (1600 aa)
D6WMH9_TRICARibonuclease H2 subunit B-like Protein. (315 aa)
D6WNB7_TRICAReplication factor C subunit 1. (985 aa)
D6WQQ2_TRICAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
Fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (381 aa)
D6WSI2_TRICADNA helicase; Belongs to the MCM family. (817 aa)
D6WSX8_TRICADNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2164 aa)
D6WVB2_TRICADNA primase large subunit-like Protein. (428 aa)
Rpa2Replication protein A 32 kDa subunit-like Protein. (254 aa)
D6WXD7_TRICADNA polymerase alpha subunit B-like Protein. (539 aa)
D6WXY2_TRICAReplication factor C subunit 2-like Protein. (354 aa)
D6WZF7_TRICAReplication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (585 aa)
D6WZI9_TRICADNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (467 aa)
D6X0G8_TRICADNA primase; Belongs to the eukaryotic-type primase small subunit family. (418 aa)
D6X269_TRICAUncharacterized protein. (118 aa)
D6X3S8_TRICADNA helicase; Belongs to the MCM family. (793 aa)
D6X470_TRICARibonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (306 aa)
D6X4M6_TRICADNA replication licensing factor Mcm2-like Protein; Belongs to the MCM family. (661 aa)
D7EHU8_TRICACBFD_NFYB_HMF domain-containing protein. (117 aa)
D7EIV8_TRICADNA helicase; Belongs to the MCM family. (778 aa)
D7EJW6_TRICAReplication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (591 aa)
RfC40Replication factor C 40kD subunit. (344 aa)
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.